Editor: "Fernando A. Oliveira"

Cellular Mechanisms in Alzheimer’s Disease

Volume 2

Personal Book: US $129 Special Offer (PDF + Printed Copy): US $219
Printed Copy: US $155
Library Book: US $516
ISSN: 2452-2554
eISSN: 2452-2562 (Online)
ISBN: 978-1-68108-716-0
eISBN: 978-1-68108-715-3 (Online)
DOI: 10.2174/97816810871531180201

Introduction

Alzheimer’s Disease (AD) is the product of the slow and progressive degenerative alteration that develops in the adult brain and can remain asymptomatic for a considerable time before cognitive deficits becomes evident. The main challenge for researchers is to identify markers of this degenerative process, and, in this sense, data has been generated through experiments bringing to light new mechanisms and hypothesis to explain its pathophysiology.

This book is a review of recent studies in AD molecular biology. Chapters explain various facets of AD, which include animal models, morphological changes, membrane composition, amyloidogenic peptides, intracellular transport systems, and the role of oxidative stress and calcium deregulation.

Readers will understand the molecular mechanisms behind AD and therefore broaden their perspective on this neurodegenerative disease and its progression.

Contributors

Editor(s):
Fernando A. Oliveira
Center for Mathematics, Computing and Cognition
Federal University of ABC – UFABC
São Paulo
Brazil




Contributor(s):
Andrea R. Vasconcelos
Pharmacology Department
Institute of Biomedical Sciences
University of São Paulo
São Paulo
Brazil


Cristoforo Scavone
Pharmacology Department
Institute of Biomedical Sciences
University of São Paulo
São Paulo
Brazil


Daniel C. Carrettiero
Center of Natural and Human Sciences
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Daniel M. Silva
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Daniela R. de Oliveira
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Elisa M. Kawamoto
Pharmacology Department
Institute of Biomedical Sciences
University of São Paulo
São Paulo
Brazil


Fernanda L. Ribeiro
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Fernando A. Oliveira
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


João C. dos Santos Silva
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Laíz C. Silva-Gonçalves
Department of Biophysics
Federal University of São Paulo
São Paulo
Brazil


Luisa Ribeiro-Silva
Department of Biophysics
Federal University of São Paulo
São Paulo
Brazil


Manoel Arcisio-Miranda
Department of Biophysics
Federal University of São Paulo
São Paulo
Brazil


Marcela B. Echeverry
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Maria C. Almeida
Center of Natural and Human Sciences
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Merari F. R. Ferrari
Department of Genetics and Evolutionary Biology
Institute for Biosciences, University of Sao Paulo
Sao Paulo
Brazil


Paula F. Kinoshita
Pharmacology Department
Institute of Biomedical Sciences, University of São Paulo
São Paulo
Brazil


Rolf M. Paninka
Department of Biophysics
Federal University of São Paulo
São Paulo
Brazil


Samanta Rodrigues
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Sonia G. Prieto
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Tatiana L. Ferreira
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil


Vitor S. Alves
Center for Mathematics, Computation and Cognition
Federal University of ABC (UFABC)
São Bernardo do Campo
São Paulo
Brazil




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