Targeted Oncometabolism: New Frontiers in Cancer Therapy – Part 1

Editors: Mithun Bhowmick, Pratibha Bhowmick, Prashant Tiwari, Steward Mudenda

Targeted Oncometabolism: New Frontiers in Cancer Therapy – Part 1

ISBN: 979-8-89881-880-7
eISBN: 979-8-89881-879-1 (Online)

Introduction

Cancer cells rewire their metabolism to fuel tumor growth, spread, and drug resistance. This book traces the field from early observations of altered glucose use to current translational practice, covering glycolysis, glutamine, lipid, and one-carbon pathways. It examines how the tumor microenvironment shapes metabolic adaptation and reviews therapeutic strategies that target these dependencies. Contributors from academia and clinical practice bridge molecular biology, immunology, and pharmacology, offering both mechanistic insight and a view toward precision-guided oncology.


Key Features

  • - Covers core metabolic pathways and their therapeutic vulnerabilities.
  • - Explores hypoxia, stromal and immune influences on metabolic heterogeneity.
  • - Reviews inhibitors, synthetic lethality, and nanotechnology delivery.
  • - Discusses single-cell metabolomics, CRISPR, and AI modeling.
  • - Links laboratory findings to patient care via case studies and trial data.

Target Readership :

Researchers, clinicians, postgraduate students, and pharmaceutical science professionals.

Contributors

Editor(s):
Mithun Bhowmick
Department of Pharmacy
Bengal College of Pharmaceutical
Sciences and Research
Durgapur, West Bengal, India


Pratibha Bhowmick
Department of Pharmacy
Bengal College of Pharmaceutical
Sciences and Research
Durgapur, West Bengal, India


Prashant Tiwari
Department of Pharmacology
College of Pharmaceutical
Sciences, Dayananda Sagar University
Bengaluru, Karnataka, India


Steward Mudenda
Department of Pharmacy
School of Health Sciences
University of Zambia
Lusaka, Zambia




Contributor(s):
Aarti Tiwari
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya (Central University)
Bilaspur, Chhattisgarh
India


Akhilesh Patel
Department of Pharmacy Practice
SGT College of Pharmacy, SGT University
Gurgaon, Haryana
India


Arpita Paul
Department of Pharmacy
Bengal College of Pharmaceutical Sciences and Research
Durgapur, West Bengal
India


Ayush Kesharwani Gupta
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya (Central University)
Bilaspur, Chhattisgarh
India


Bhavana Alaparthi
KVSR Siddhartha College of Pharmaceutical Sciences
Vijayawada, Andhra Pradesh
India


Chitra Vellapandian
Department of Pharmacology
SRM College of Pharmacy, SRM Institute of Science and Technology
Kattankulathur, Chengalpattu District, Tamil Nadu
India


Chowdhury Mobaswar Hossain
Department of Pharmaceutical Technology
Maulana Abul Kalam Azad University of Technology
Haringhata, West Bengal
India


Girisha Sagar
Department of Pharmaceutics, College of Pharmaceutical Sciences
Dayananda Sagar University
Bengaluru, Karnataka
India


Hiba Parveen
Faculty of Pharmacy
Veer Madho Singh Bhandari Uttarakhand Technical University, Dehradun. School of Health Sciences, Dayananda Sagar University
Dehradun, Uttarakhand
India


Jasimuddin Mallick
Department of Pharmaceutical Technology
Maulana Abul Kalam Azad University of Technology
Haringhata, West Bengal
India


Junaid Tantray
Department of Pharmacology
NIMS Institute of Pharmacy, NIMS University
Jaipur, Rajasthan
India


Kanaka Durga Devi Nelluri
KVSR Siddhartha College of Pharmaceutical Sciences
Vijayawada, Andhra Pradesh
India


Lakshmi Kanakaraj
Department of Pharmaceutical Chemistry, Chettinad School of Pharmaceutical Sciences
Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education
Kelambakkam, Tamil Nadu
India


Meenakshi Jaiswal
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya
Bilaspur, Chhattisgarh
India


Minakshi Kommoju
KVSR Siddhartha College of Pharmaceutical Sciences
Vijayawada, Andhra Pradesh
India


Mithun Bhowmick
Department of Pharmacy
Bengal College of Pharmaceutical Sciences and Research
Durgapur, West Bengal
India


Muthukumaran Thulasingam
Department of Pharmacology, Chettinad School of Pharmaceutical Sciences
Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education
Kelambakkam, Tamil Nadu
India


Naureen Afrose
Division of Pharmaceutics
Dr. B. C. Roy College of Pharmacy and AHS
Durgapur, West Bengal
India


Nazmun Lyle
Department of Physiology
Hi-Tech Medical College and Hospital
Rourkela, Odisha
India


Nidhi Agrawal
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya
Bilaspur, Chhattisgarh
India


Pinkesh Sahu
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya (Central University)
Bilaspur, Chhattisgarh
India


Pradeep Kumar Samal
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya (Central University)
Bilaspur, Chhattisgarh
India


Prantika Mondal
Department of Pharmacy
Bengal College of Pharmaceutical Sciences and Research
Durgapur, West Bengal
India


Prashant Tiwari
Department of Pharmacology, College of Pharmaceutical Sciences
Dayananda Sagar University
Bengaluru, Karnataka
India


Prashant Tiwari
Department of Pharmacology, College of Pharmaceutical Sciences
Dayananda Sagar University
Bengaluru, Karnataka
India


Pratibha Bhowmick
Department of Pharmacy
Bengal College of Pharmaceutical Sciences and Research
Durgapur, West Bengal
India


Prativa Bhowmick
Department of Pharmacy
Bengal College of Pharmaceutical Sciences and Research
Durgapur, West Bengal
India


Rashmi Dewangan
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya
Bilaspur, Chhattisgarh
India


Rideb Chakraborty
NSHM Institute of Pharmaceutical Technology, NSHM Knowledge Campus
Durgapur, West Bengal
India


S.K. Abdul Rahaman
Department of Pharmaceutical Sciences
Vignan's Foundation for Science, Technology and Research (Deemed to be University)
Guntur, Andhra Pradesh
India


S.K. Lanjhiyana
Department of Pharmacy
Guru Ghasidas Vishwavidyalaya
Bilaspur, Chhattisgarh
India


Sabyasachi Choudhuri
Department of Pharmaceutical Technology
Maulana Abul Kalam Azad University of Technology
Haringhata, West Bengal
India


Sanjay Nagdev
Department of Pharmacy Practice
ISF College of Pharmacy
Moga, Punjab
India


Satheeshkumar Sellamuthu
Department of Pharmaceutical Chemistry
Karpagam College of Pharmacy
Coimbatore, Tamil Nadu
India


Sheikh Mohammad Faisal
Department of Quality Assurance
Shri Prakashchand Jain College of Pharmacy and Research
Jamner, Maharashtra
India


Shouvik Kumar Nandy
Department of Pharmacy
Bengal College of Pharmaceutical Sciences and Research
Durgapur, West Bengal
India


Sourajyoti Goswami
Department of Pharmacy
Bengal College of Pharmaceutical Sciences and Research
Durgapur, West Bengal
India


Steward Mudenda
Department of Pharmacy, School of Health Sciences
University of Zambia
Lusaka
Zambia


Suparba Tribedi
Department of Pharmaceutical Technology
Maulana Abul Kalam Azad University of Technology
Haringhata, West Bengal
India