Introduction
Cancer cells rewire their metabolism to fuel tumor growth, spread, and drug resistance. This book traces the field from early observations of altered glucose use to current translational practice, covering glycolysis, glutamine, lipid, and one-carbon pathways. It examines how the tumor microenvironment shapes metabolic adaptation and reviews therapeutic strategies that target these dependencies. Contributors from academia and clinical practice bridge molecular biology, immunology, and pharmacology, offering both mechanistic insight and a view toward precision-guided oncology.
Key Features
- - Covers core metabolic pathways and their therapeutic vulnerabilities.
- - Explores hypoxia, stromal and immune influences on metabolic heterogeneity.
- - Reviews inhibitors, synthetic lethality, and nanotechnology delivery.
- - Discusses single-cell metabolomics, CRISPR, and AI modeling.
- - Links laboratory findings to patient care via case studies and trial data.
Target Readership :
Researchers, clinicians, postgraduate students, and pharmaceutical science professionals.
