Author: Genovefa Kolovou

Women's Heart and Estrogens

eBook: US $129 Special Offer (PDF + Printed Copy): US $236
Printed Copy: US $171
Library License: US $516
ISBN: 978-1-68108-113-7 (Print)
ISBN: 978-1-68108-112-0 (Online)
Year of Publication: 2015
DOI: 10.2174/97816810811201150101


Cardiovascular mortality in women is more frequent than breast cancer mortality, a fact which is often overlooked. Women's Heart and Estrogens explores this important women’s health issue with respect to estrogen levels (before and after menopause) as the hormone has been known to mediate cardiovascular effects in women. The handbook includes a description of the structure and biological activity of estrogen and follows up with a detailed reference on the genetics behind estrogen and its effect on the cardiovascular system. Subsequent chapters cover the effects of estrogens on the stages of atherogenesis, actions of estrogens on the vascular wall and on cardiovascular metabolic pathways, causes leading to the development of early onset of coronary heart disease in young women (such as vasculitis and autoimmune diseases), hypercoagulable states, myocardial infarction in hallucinogenic drug abusers, non-atherosclerotic and atherosclerotic coronary heart disease, hormone replacement therapy and postmenopausal risk factors. Medical professionals will also find handy guidelines for cardiovascular disease prevention in women.

Women's Heart and Estrogens offers knowledge to readers in a clear and simple manner with detailed images and summaries in each chapter. Guidelines are also presented in a chronological context which demonstrates the development of cardiovascular disease prevention and risk management strategies for women over the years.


I read Genovefa’s book with pleasure although it is dealing with complicated subjects such as women’s heart.

The book is generously offering knowledge, which is presented with clarity, simplicity and elegancy. The book initiates with a description of the established and newly proposed metabolic pathways involving estrogen actions and ends with more recent published studies and recommendations.

Genovefa writing her thirteen book took care in exhausting every option of the women’s heart and lead reader to solve all their queries.

In the first two chapters there has been a referral to a very important issue such as estrogens involvement in cardiovascular system and atherogenesis. Moreover, the classification of causes leading to the development of early onset of coronary heart disease in young women is particularly useful. The differences observed in the lipid profile, obesity, and levels of the blood glucose and blood pressure of peri- or post-menopausal women are described in the 3rd chapter.

Also, the studies involving women treated with hormone replacement therapy and cardiovascular outcomes are summarized nicely in chapter 4. Furthermore, after analyzing the prevention of cardiovascular disease in women, in chapter 5, guidelines according to prevention of cardiovascular disease in women (chapter 6) are also presented. The guidelines are analyzed according to published date, which allows reader to go through the 15-year development of current guidelines.

Moreover, the significant parts of this important work are played by figures and main points, which summarized each chapter. This allows reader the quick comeback to the chapter.

I wish all the best with your new book.

Helen Bilianou, MD
Director, Cardiology Department
Kalithea, Athens,
Head of Lipid Clinic, Tzanio Hospital, Greece


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