Editors: Bashir Matata, Maqsood Elahi, Priscilla Day-Walsh

Blood Oxidant Ties: The Evolving Concepts in Myocardial Injury and Cardiovascular Disease

eBook: US $49 Special Offer (PDF + Printed Copy): US $78
Printed Copy: US $54
Library License: US $196
ISBN: 978-981-5165-02-9 (Print)
ISBN: 978-981-5165-01-2 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151650121230101

Introduction

Blood Oxidant Ties: The Evolving Concepts in Myocardial Injury and Cardiovascular Disease is an update on the recent advances in the development of antioxidant-based therapies. It starts with an overview of the mechanisms underlying the genesis of oxidative stress, summarizing the link between oxidative stress and a number of cardiovascular conditions. This is followed by an explanation of how oxidative stress interacts with lipid metabolism and the placental environment. Three chapters on the role of antioxidant-based therapy for cardiovascular diseases round up the book.

Key Features

  • - Outlines several cell-signaling pathways that are modulated by the interplay between reducing and oxidizing agents (redox status) and gene expression in the cardiovascular disease process
  • - Brings information about maternal programming environment in the placenta
  • - Covers development of novel nanotechnology-based antioxidant delivery systems for effective drug delivery
  • - Includes references for further reading

The book is aimed at a broad readership of scientific and medical professionals involved in research on cardiovascular diseases, pathophysiology, pharmacy, pharmaceutical science and life sciences. It also serves as a reference for scholars who want to understand the complex biochemical mechanisms of antioxidant agents.

Audience

Scientific and medical professionals involved in research on cardiovascular diseases, pathophysiology, pharmacy, pharmaceutical science and life sciences; scholars who want to understand the complex biochemical mechanisms of anti-oxidant agents.

Foreword

- Pp. i
Sarabjit Mastana
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Preface

- Pp. ii-iii (2)
Bashir Matata
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List of Contributors

- Pp. iv

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Redox Signaling, Oxidative Stress in Cardiovascular Disease –basic Science and Clinical Aspects

- Pp. 1-24 (24)
Bashir Matata*, Maqsood Elahi

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Oxidative Stress and Leukocytes Activation - The Two Keystones of Ischemia/Reperfusion Injury during Myocardial Infarction, Valve Disease, and Atrial Fibrillation

- Pp. 25-44 (20)
Bashir Matata*, Maqsood Elahi

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Lipids, Oxidation, and Cardiovascular Disease

- Pp. 45-64 (20)
Priscilla Day-Walsh*

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Maternal Factors and the Placenta: A Programming Environment for Cardiovascular Disease

- Pp. 65-89 (25)
Wai Lok Whitney Ching, Priscilla Day-Walsh, Amanda Sferruzzi-Perri*

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The Emerging Role of Microbiome in Cardiovascular Diseases

- Pp. 90-111 (22)
Emad Shehata, Priscilla Day-Walsh*

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Oxidants and Antioxidants Interplay in the Modulation of Inflammation and Cardiovascular Disease

- Pp. 112-127 (16)
Bashir Matata*, Maqsood Elahi

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Prevention of Reperfusion Injury in Acute Myocardial Infarction: A “flashback” Journey of Novel Strategies Based on the Potential Therapeutic Role of Antioxidants

- Pp. 128-147 (20)
Francisco Salazar-Cornejo, Abraham Gajardo, Marcelo J. Kogan, Ramón Rodrigo*

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Improvement of Nitric Oxide Availability in Myocardial Ischemia/reperfusion: Role of Nanotechnology as a Therapeutic Approach

- Pp. 148-166 (19)
Marcelo J Kogan*, Francisco Salazar-Cornejo, Abraham Gajardo, Ramón Rodrigo*

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Subject Index

- Pp. 167-171 (5)
Bashir Matata, Maqsood Elahi, Priscilla Day-Walsh
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