Authors: V. V. Sathibabu Uddandrao, Parim Brahma Naidu

Advancements in Cardiovascular Research and Therapeutics: Molecular and Nutraceutical Perspectives

eBook: US $59 Special Offer (PDF + Printed Copy): US $94
Printed Copy: US $65
Library License: US $236
ISBN: 978-981-5050-84-4 (Print)
ISBN: 978-981-5050-83-7 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150508371220101


This reference summarizes recent advancements in knowledge about cardiovascular disease and pharmacology. The goal of the book is to inform readers about recent findings on cardiovascular therapeutics and how to conduct experiments to evaluate natural products. It presents 10 chapters that cover basic clinical research on cardiovascular diseases and therapeutic agents derived from natural sources. The book concludes with a series of experiments that demonstrate the methods to test the ameliorative effects of 3 phytochemicals: Biochanin A (red clover), Zingiberene (ginger oil) and Betaine (sugar beet).

Key Features:

- 10 chapters that highlight recent research cardiovascular medicine and pharmacology

- Covers knowledge about basic cardiovascular physiology, congestive heart failure treatment and the treatment of heart inflammation.

- Covers uses, benefits, and drawbacks of numerous rodent and non-rodent animal models for studying CVD

- Updates readers about 21st-century CRISPR-cas9 technology and its uses in CVD.

- Covers the significance of Indian Ayurvedic techniques on the cardiovascular system,

- Covers information about nutraceuticals for CVD therapy

- Includes experiments to evaluate 3 phytochemicals for the treatment of different heart diseases such as hypertension, obesity-cardiomyopathy and the mitigation of inflammatory cytokines in myocardial infarction.

This book is an informative resource for cardiologists, and researchers working in the field of cardiovascular pharmacology. It also helps readers to understand the benefits of herbal medications that are commonly available for consumption in homes.


- Pp. i
Ramachandra Subbaraya Gudde
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- Pp. ii
V. V. Sathibabu Uddandrao, Parim Brahma Naidu
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List of Contributors

- Pp. iii-v (3)

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Cardiovascular Diseases and Nutraceuticals: Underlying Mechanism and Therapeutic Biomarkers

- Pp. 1-24 (24)
Pallavi Saxena, Vinod Kumar, Noopur Khare, Neeraj Pal, Dibyabhaba Pradhan, Pradeep K Chaturvedi, Arun Kumar Jain, Manoj Kumar, V. V. Sathibabu Uddandrao, Umesh Kumar*
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Congestive Heart Failure: Insight on Pharmacotherapy

- Pp. 25-37 (13)
Sri Bharathi G.S*, Sakthi Sundaram S, Prabhakaran S, Lalitha V, Haja Sherief S, Duraisami R, Sengottuvelu S
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Diet, Inflammation and Cardiovascular Disorders

- Pp. 38-51 (14)
M Kesavan*, HV Manjunathachar*
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Rodent and Non-Rodent Animal Models for CardioVascular Diseases

- Pp. 52-78 (27)
Irfan Ahmad Mir*, HV Manjunathachar*, R Ravinda Naik, SSYH Qadri, Taniya Saleem
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Application of 21st Century Genetic Engineering Tools and CRISPR-Cas9 Technologies to Treat Most Advanced Cardiovascular Diseases of Humans

- Pp. 79-103 (25)
J. Venkateshwara Rao*, R. Ravindar Naik, S. Venkanna, N. Ramesh Kumar
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Role of Vyana Vayu in CardioVascular System, Etiopathogenesis and Therapeutic Strategies: An Ayurveda Perspective

- Pp. 104-124 (21)
Savitri Vasudev Baikampady*, C. S. Hiremath, Reeta Varyani, Venketesh
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Nutraceuticals: The Potential Agents to Rescue Human Race from Cardiovascular Diseases (CVDs)

- Pp. 125-155 (31)
Sreedevi Gandham, Ghali EN Hanuma Kumar, Balaji Meriga*
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Ameliorative Potential of Biochanin-A against Dexamethasone Induced Hypertension through Modulation of Relative mRNA and Protein Expressions in Experimental Rats

- Pp. 156-170 (15)
V. V. Sathibabu Uddandrao*, P. P. Sethumathi, Parim Brahma Naidu, S. Vadivukkarasi, Mustapha Sabana Begum, G. Saravanan*
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Zingiberene, an Active Constituent from Zingiber officinale Ameliorated High-Fat Diet-Induced Obesity Cardiomyopathy in Rats

- Pp. 171-185 (15)
S. Jaikumar, G. Somasundaram, S. Sengottuvelu*
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Betaine, a Nutraceutical Ameliorated Myocardial Infarction by Attenuation of Pro-Inflammatory Cytokines and Matrix Metalloproteinase Production in Rats

- Pp. 186-200 (15)
G. Somasundaram*, S. Jaikumar, S. Sengottuvelu
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Subject Index

- Pp. 201-215 (15)

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