Editors: Adilson Beatriz, Dênis Pires de Lima

Recent Advances in the Synthesis of Organic Compounds to Combat Neglected Tropical Diseases

eBook: US $49 Special Offer (PDF + Printed Copy): US $143
Printed Copy: US $119
Library License: US $196
ISBN: 978-1-60805-903-4 (Print)
ISBN: 978-1-60805-902-7 (Online)
Year of Publication: 2014
DOI: 10.2174/97816080590271140101

Introduction

The World Health Organization (WHO) has reported 14 diseases that are occurring exclusively in tropical areas. Most of these diseases are infectious and mainly affect poor populations. Some of these diseases include malaria, dengue fever, leishmaniasis and Chagas disease. Therefore, an acute need for increasing the arsenal of drugs is required to fight against these neglected diseases for the guaranteed recovery and relief of many patients.

This E-book gathers important scientific research performed by scientists worldwide showing the state of the art of Medicinal Chemistry dedicated to the synthesis of compounds that are potentially bioactive against the causative agents of neglected diseases.

The contents of this book include chapters on recent advances in synthetic organic compounds for the prevention of Chagas disease, recent advances in the discovery of small organic molecules for the prevention and treatment of dengue fever, leishmaniasis, leprosy, therapeutic arsenal and drug discovery for lymphatic filariasis, therapeutic agents for the treatment of malaria, schistosomiasis and synthetic organic compounds as potential antitubercular drugs.

This book is intended for undergraduate and graduate students in institutes, colleges, universities and academies who want to specialize in the field of organic synthesis and medicinal chemistry. This book will also be a valuable resource of information for researchers in this field.

Contributors

Editor(s):
Adilson Beatriz
Federal University of Mato Grosso do Sul
Brazil


Dênis Pires de Lima
Federal University of Mato Grosso do Sul
Brazil




Contributor(s):
Aquino Vitor Hugo
Department of Clinical
Faculty of Pharmaceutical Sciences of Ribeirão Preto
University of São Paulo
Ribeirao Preto – SP
Brazil


Boechat Nubia
Department of Organic Synthesis
Institute of Drug Technology - Farmanguinhos
Oswaldo Cruz Foundation - Fiocruz
Rio de Janeiro-RJ
Brazil


Bosquesi Priscila Longhin
Faculty of Pharmaceutical Sciences
Paulista State University- UNESP
Araraquara-SP
Brazil


Braga Saulo Fehelberg Pinto
Laboratory of Pharmaceutical Chemistry
Faculty of Pharmacy
Faculty of Pharmacy
Federal University of Minas Gerais
Belo Horizonte-MG
Brazil


Chin Chung M.
Departamento de Fármacos e Medicamentos
Faculty of Pharmaceutical Sciences
Paulista State University-UNESP
Araraquaara-SP
Brazil


de Lima Davidson Pires
Department of Clinical Medicine
Faculty of Medicine
Federal University of Minas Gerais
Belo Horizonte-MG
Brazil


de Lima Dênis Pires
Institute of Chemistry
Federal University of Mato Grosso do Sul
Campo Grande-MS
Brazil


Emery Flávio da Silva
Department of Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences of Ribeirão Preto – FCFRP
University of São Paulo - USP
Ribeirao Preto – SP
Brazil


Fernandes Guilherme F. dos Santos
Faculty of Pharmaceutical Sciences
Paulista State University- UNESP
Araraquara-SP
Brazil


Ito Felicia Megumi
Federal Institute of Mato Grosso do Sul.
Rua Tanure Salime
Coxim-MS
s/n, 79400-000
Brazil


Leite Clarice Q. F.
Laboratory of Mycobacteriology “Prof. Dr. Hugo David”
Department of Biological Science
Faculty of Pharmaceutical Sicences
Paulista State University
UNESP
Jaú-SP
Brazil


Lopes Marcela Silva
Laboratory of Pharmaceutical Chemistry
Faculty of Pharmacy
Federal University of Minas Gerais
Belo Horizonte-MG
Brazil


Marino Leonardo B.
Laboratory of Mycobacteriology “Prof. Dr. Hugo David”
Department of Biological Science
Faculty of Pharmaceutical Sicences
Paulista State University
UNESP
Jaú-SP
Brazil


Micheletti Ana Camila
Institute of Chemistry
Federal University of Mato Grosso do Sul
Campo Grande-MS
Brazil


Natsui Ana Patricia Yatsuda
Department of Clinical
Toxicological and Bromatological Analyses
Faculty of Pharmaceutical Sciences of Ribeirao Preto
São Paulo University- USP
Ribeirão Preto-SP
Brazil


Neves Filho Ricardo A.W.
Department of Bioorganic Chemistry
Leibniz Institute of Plant Biochemistry
São Paulo University- USP
Weinberg
Germany


Oliveira Renata Barbosa de
Laboratory of Pharmaceutical Chemistry
Faculty of Pharmacy
Federal University of Minas Gerais
Belo Horizonte-MG
Brazil


Oliveira Ronaldo Nascimento de
Laboratory of Synthesis of Bioactive Compounds
Department of Molecular Sciences
Federal Rural University of Pernambuco
Recife-PE
Brazil


Pavan Fernando Rogério
Laboratory of Mycobacteriology “Prof. Dr. Hugo David”
Department of Biological Science
Faculty of Pharmaceutical Sicences
Paulista State University
UNESP
Jaú-SP
Brazil


Pinheiro Luiz Carlos da Silva
Department of Organic Synthesis
Institute of Drug Technology - Farmanguinhos
Oswaldo Cruz Foundation- Fiocruz
Paulista State University
Rio de Janeiro-RJ
Brazil


Rezende Lucas Cunha Dias
Department of Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences of Riberão Preto – FCFRP
University of São Paulo
Paulista State University- USP
Ribeirao Preto – SP
Brazil


Santos Edson dos Anjos dos
Federal Technological University of Paraná
Apucarana-PR
Brazil


Santos Edson dos Anjos dos
Federal Technological University of Paraná
Apucarana-PR
Brazil


Santos Gabriela Bianchi dos
Department of Pharmaceutical Sciences
Faculty of Pharmaceutical Sciences of Ribeirão Preto - FCFRP
São Paulo University - USP
Ribeirão Preto-SP
Brazil


Santos Jean Leandro
Faculty of Pharmaceutical Sciences
Paulista State University- UNESP
Araraquara-SP
Brazil




RELATED BOOKS

.Science of Spices and Culinary Herbs - Latest Laboratory, Pre-clinical, and Clinical Studies.
.Science of Spices and Culinary Herbs - Latest Laboratory, Pre-clinical, and Clinical Studies.
.Medicinal Chemistry of Drugs Affecting the Nervous System.
.Advances in Anticancer Agents in Medicinal Chemistry.