Editor: Simone Peschillo

Series Title: Frontiers in Neurosurgery

Brain Ischemic Stroke - From Diagnosis to Treatment

Volume 3

eBook: US $139 Special Offer (PDF + Printed Copy): US $255
Printed Copy: US $186
Library License: US $556
ISSN: 2405-7401 (Print)
ISSN: 2405-741X (Online)
ISBN: 978-1-68108-310-0 (Print)
ISBN: 978-1-68108-309-4 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810830941160301


Stroke is thought to be the second biggest killer worldwide, and is responsible for over 5 million deaths per year. Several strategies have been developed to enhance treatment of stroke patients. Multimodal neuroimaging allows physicians to diagnose and evaluate not only the ischemic core but also the vessel pattern and collateral status. Stroke Treatment involves extensive intravenous drug administration. Several new drugs with long lasting efficacy are now being tested in randomized clinical trials. In this context, endovascular treatment is a promising avenue that allows physicians to treat patients in extended time windows especially patients in whom intravenous RTPA has failed. A new era has emerged with new devices called stent retrievers and aspiration techniques, which have demonstrated higher rates of recanalization and clear superiority over previous devices employed in RCTs. The third volume of Frontiers in Neurosurgery presents updated information on ischemic stroke treatment. The volume comprehensively covers the epidemiology, physiology, diagnosis and treatment modalities of stroke. Readers will also find key information on diagnosing and treating rare and lesser known causes of stroke as well as notes about new devices and medical procedures to combat ischemic stroke. This volume is a useful resource for neurosurgery specialists as well as nurses, physiotherapists and caregivers.


- Pp. i-iv (4)
Jaques Théron
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- Pp. v-vi (2)
Simone Peschillo
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List of Contributors

- Pp. vii-viii (2)
Simone Peschillo
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Epidemiology and Social Costs

- Pp. 3-22 (20)
Simone Peschillo, Francesco Diana
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Brain Ischemia and Stroke: Mechanisms and Opportunities

- Pp. 23-54 (32)
Francesco Orzi, Barbara Casolla
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New Imaging Techniques

- Pp. 55-94 (40)
Elena Fontana, Alessandro Boellis, Lara Cristiano, Alessandro Bozzao
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Medical Acute Stroke Treatment

- Pp. 95-121 (27)
Paolo Candelaresi, Alfonso Ciccone
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Endovascular Stroke Therapy: Devices and Different Approaches

- Pp. 122-151 (30)
Daniele G. Romano, Samuele Cioni, Sandra Bracco
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Mechanical Thrombectomy for Acute Ischemic Stroke: Review of the Evidence

- Pp. 152-169 (18)
Italo Linfante
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Neurosurgery in Brain Ischemic Stroke

- Pp. 170-184 (15)
Paolo Missori, Cristina Mancarella
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Clinical, Pharmacological and Endovascular Management of Cerebral Venous Thrombosis

- Pp. 185-214 (30)
Federico Di Maria, Flore Baronnet-Chauvet, Charlotte Rosso, Frederic Clarençon
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Intracranial Stenosis: Medical and Endovascular Management

- Pp. 215-236 (22)
Alessandro Stecco, Paolo Machì
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Uncommon Cause of Stroke: Diagnosis and Treatment (Part I)

- Pp. 237-375 (139)
Paolo Cerrato, Alessandro Pezzini, Giovanna Vaula
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Uncommon Cause of Stroke: Diagnosis and Treatment (Part II)

- Pp. 376-473 (98)
Paolo Cerrato, Alessandro Pezzini, Giovanna Vaula
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Endovascular Management of Atherosclerotic and Dissected Carotids

- Pp. 474-497 (24)
Guglielmo Pero, Themistoklis Papasilekas
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Intensive Care Management

- Pp. 498-510 (13)
Federico Bilotta, Martina Novelli, Filippo Pecorari, Giovanni Rosa
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The Trials and Tribulations of Ischemic Stroke Therapy

- Pp. 511-528 (18)
Arani Bose, Sophia S. Kuo, Jennifer Wong, John Lockhart, Siu Po Sit
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Evolution of Devices for Endovascular Thrombectomy in Acute Ischemic Stroke: From the Beginning to the Adapt Technique

- Pp. 529-545 (17)
Simone Peschillo, Francesco Diana
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Subject Index

- Pp. 546-561 (16)
Simone Peschillo
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