Editor: Vasilios E. Papaioannou

Series Title: Frontiers in Myocardia

Septic Cardiomyopathy: from bench-to-bedside

Volume 1

eBook: US $129 Special Offer (PDF + Printed Copy): US $219
Printed Copy: US $155
Library License: US $516
ISSN: 2451-8344 (Print)
ISSN: 2451-8352 (Online)
ISBN: 978-1-68108-061-1 (Print)
ISBN: 978-1-68108-060-4 (Online)
Year of Publication: 2015
DOI: 10.2174/97816810806041150101


Frontiers in Myocardia is an eBook series which compiles information about the structure and function of myocardial (the heart muscles) and includes updated reviews on the recent developments in the treatment of associated diseases such as angina, cardiac arrhythmias and myocardial infarction.

Advances in research on clinical sepsis in the last few decades have lead to the use of new concepts and treatment paradigms that have been tested and implemented in the clinical setting of Intensive Care Units around the world. An integrative approach towards understanding the pathophysiology of cardiac dysfunction in septic patients can, therefore, lead to better patient outcomes.

The first volume of this series, Septic Cardiomyopathy: from bench-to-bedside, integrates new and old information about the molecular mechanisms, histopathological and electrophysiological alterations with novel findings for diagnosing treating septic cardiomyopathy. This eBook attempts to bridge the gap between basic and clinical scientists and presents new data on different aspects of cardiac physiology during critical illness in a single volume. Chapters in this volume also cover cardiovascular changes that occur as a consequence of sepsis including metabolic, mitochondrial arrhythmic changes.

This eBook will add significant value to medical students, cardiac physicians and medical scientists engaged in the field of critical care medicine.


- Pp. i
Michael R. Pinsky
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- Pp. ii-iii (2)
Vasilios E. Papaioannou
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List of Contributors

- Pp. iv-v (2)
Vasilios E. Papaioannou
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- Pp. vi
Vasilios E. Papaioannou
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Potential Pathophysiological Mechanisms in Septic Cardiomyopathy: an Overview

- Pp. 3-40 (38)
Karl Werdan, Sebastian Nuding, Ursula Müller-Werdan
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Cellular and Molecular Mechanisms of Septic Cardiomyopathy

- Pp. 41-56 (16)
Jamison J. Grailer, Peter A. Ward
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Cellular Electrophysiological Mechanisms in Septic Cardiomyopathy

- Pp. 57-84 (28)
Brigitte Pelzmann, Susanne Scheruebel, Klaus Zorn-Pauly
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Septic Cardiomyopathy: A Distinct Histopathological Entity

- Pp. 85-103 (19)
Maria José Figueiredo, Ana Caroline Silva de Freitas, Érica Carolina Campos, Danilo Figueiredo Soave, Simone Gusmão Ramos, Mara Rúbia N. Celes
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Septic Cariomyopathy: A Distinct Metabolic and Genetic Entity?

- Pp. 104-115 (12)
Jochen Hinkelbein
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Clinical and Molecular Aspect of Septic Cardiomyopathy: Basic Concepts

- Pp. 116-131 (16)
Gilles Clermont
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The Clinical Aspects of Septic Myocardiopathy

- Pp. 132-139 (8)
Sabri Soussi, Matthieu Legrand
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Septic Cardiomyopathy: an Echocardiographic Approach

- Pp. 140-153 (14)
Hélène Nougue, Alexandre Mebazaa, Etienne Gayat
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Which Biomarkers Can I Use to Manage Septic Cardiomyopathy

- Pp. 154-163 (10)
Anaïs Caillard, Etienne Gayat, Dahdouh Souheila, Alexandre Mebazaa
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Current and New Therapeutic Interventions in Septic Cardiomyopathy

- Pp. 164-175 (12)
Daniel De Backer
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Tachycardia and Its Pathophysiological Implications in Septic Myocardial Dysfunction

- Pp. 176-187 (12)
Andrea Morelli, Maurizio Passariello
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Septic Cardiomyopathy: Quo Vadis? From Past-to-the Future

- Pp. 188-212 (25)
James J. Douglas, John H. Boyd, Keith R. Walley
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Subject Index

- Pp. 213-214 (2)
Vasilios E. Papaioannou
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