Editor: Jianxun Song

Series Title: Frontiers in Cancer Immunology

Cancer Immunotherapy: Mechanisms of Cancer Immunity, Engineering Immune-Based Therapies and Developing Clinical Trials

Volume 1

eBook: US $99 Special Offer (PDF + Printed Copy): US $178
Printed Copy: US $129
Library License: US $396
ISSN: 2405-9102 (Print)
ISSN: 2405-9110 (Online)
ISBN: 978-1-68108-049-9 (Print)
ISBN: 978-1-68108-048-2 (Online)
Year of Publication: 2015

Introduction

Clinicians, patients and scientists, alike, have been battling cancer for over several decades; however, patient outcomes have not significantly improved over the years with conventional therapies. In recent years, this has caused researchers to look for a change in the status quo, and, the awareness of the human immune system, which has an intrinsic mechanism to control microbial pathogens and dysfunctional self-tissues, has triggered scientists to look for new modes of cancer therapy. Cancer Immunotherapy has become a major research field as a result of these efforts, gaining some recognition for notable breakthroughs in cancer patient prognosis. Frontiers in Cancer Immunology collectively presents the methods which have been studied and used in cancer immunotherapy based on the different components of human immune system. The series will give clinicians and immunologists a roadmap of current trends in all branches of cancer immunology. This volume lists the major immune system components (such as T cells and NK cells and associated antigens/antibodies) which have been demonstrated to limit the growth of or kill tumor cells. Relevant applications in cancer therapy are also included in addition to a general introduction to engineered as well as targeted cancer immunotherapies (cancer vaccines).

Contributors

Editor(s):
Jianxun Song
Department of Microbiology and Immunology
The Pennsylvania State University College of Medicine
Hershey
PA 17033
USA




Contributor(s):
Adam W. Mailloux
H. Lee Moffitt Cancer Center
SRB 23033, Tampa
FL 33612
USA


Anatoliy Markiv
Faculty of Sciences and Technology
University of Westminster
London
UK


Carol A. Kruse
Department of Neurosurgery
David Geffen School of Medicine,University of California
Los Angeles
CA 90095
USA


Colin C. Malone
Department of Neurosurgery
David Geffen School of Medicine,University of California
Los Angeles
CA 90095
USA


Elena I. Fomchenko
Department of Neurosurgery
David Geffen School of Medicine,University of California
Los Angeles
CA 90095
USA


Fengyang Lei
Department of Microbiology and Immunology
The Pennsylvania State University College of Medicine
Hershey
PA 17033
USA


Hiroshi Kawamoto
Department of Immunology
Institute for Frontier Medical Sciences, Kyoto University
Kyoto 606-8507
Japan


Ivan Shevchenko
Skin Cancer Unit, German Cancer Research Center, Heidelberg and Department of Dermatology, Venereology and Allergology
University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg
Mannheim
Germany


Jianxun Song
Department of Microbiology and Immunology
The Pennsylvania State University College of Medicine
Hershey
PA 17033
USA


Kate L. Erickson
Department of Neurosurgery
David Geffen School of Medicine, University of California
Los Angeles
CA 90095
USA


Kazuya Ofuji
Division of Cancer Immunotherapy
Exploratory Oncology Research and Clinical Trial Center, National Cancer Center
Japan


Kristin Fino
Department of Microbiology and Immunology
The Pennsylvania State University College of Medicine
Hershey
PA 17033
USA


Linda M. Liau
Department of Neurosurgery
David Geffen School of Medicine, University of California
Los Angeles
CA 90095
USA


Mayuko Sakai
Division of Cancer Immunotherapy
Exploratory Oncology Research and Clinical Trial Center, National Cancer Center
Japan


Megan C. Duggan
Comprehensive Cancer Center
The Ohio State University
Columbus
OH 43210
USA


Ming-Song Li
Department of Gastroenterology
Nanfang Hospital, Southern Medical University
Guangzhou
China


Mohammad Haque
Department of Microbiology and Immunology
The Pennsylvania State University College of Medicine
Hershey
PA 17033
USA


Pearlie K. Epling-Burnette
H. Lee Moffitt Cancer Center, SRB 23033
Tampa
FL 33612
USA


Richard G. Everson
Department of Neurosurgery
David Geffen School of Medicine, University of California
Los Angeles
CA 90095
USA


Robert M. Prins
Department of Neurosurgery
David Geffen School of Medicine, University of California
Los Angeles
CA 90095
USA


Stephen Gottschalk
Center for Cell and Gene Therapy, Texas Children’s Hospital
Houston Methodist Hospital, Baylor College of Medicine
Houston
Texas
USA
/
Department of Pediatrics, and Pathology and Immunology
Baylor College of Medicine
Houston
Texas
USA


Steven De Vleeschouwer
Department of Neurosciences
Experimental Neurosurgery and Neuroanatomy
KU Leuven
Belgium


Tania G. Rodríguez-Cruz
Center for Cell and Gene Therapy, Texas Children’s Hospital
Houston Methodist Hospital, Baylor College of Medicine
Houston
Texas
USA


Tetsuya Nakatsura
Division of Cancer Immunotherapy
Exploratory Oncology Research and Clinical Trial Center, National Cancer Center
Japan


Toshiaki Yoshikawa
Division of Cancer Immunotherapy
Exploratory Oncology Research and Clinical Trial Center, National Cancer Center
Japan


Viktor Umansky
Skin Cancer Unit, German Cancer Research Center, Heidelberg and Department of Dermatology, Venereology and Allergology
University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg
Heidelberg
Germany


William E. Carson III
Comprehensive Cancer Center
The Ohio State University
Columbus
OH 43210
USA


Xiaofang Xiong
Department of Microbiology and Immunology
The Pennsylvania State University College of Medicine
Hershey
PA 17033
USA


Xue-Feng Bai
Department of Pathology and Comprehensive Cancer Center
The Ohio State University
Columbus
OH
USA


Yangbing Zhao
Department of Pathology and Laboratory Medicine,Abramson Family Cancer Research Institute
Perelman School of Medicine, University of Pennsylvania
Philadelphia
PA 19104
USA


Yu Sawada
Division of Cancer Immunotherapy
Exploratory Oncology Research and Clinical Trial Center, National Cancer Center
Japan


Yun Shi
Department of Pathology and Comprehensive Cancer Center
The Ohio State University
Columbus
OH
USA
/
Department of Gastroenterology
Nanfang Hospital, Southern Medical University
Guangzhou
China


Zhenzhen Liu
Department of Pathology and Comprehensive Cancer Center
The Ohio State University
Columbus
OH
USA




RELATED BOOKS

.Frontiers in Clinical Drug Research - Anti-Cancer Agents.
.Advances in Cancer Nanotheranostics for Experimental and Personalized Medicine.
.Current Advances in Breast Cancer Research: A Molecular Approach.
.Avastin and Malignant Gliomas .