Editor: Atta-ur-Rahman

Frontiers in Clinical Drug Research – Alzheimer Disorders

Volume 1

eBook: US $129 Special Offer (PDF + Printed Copy): US $219
Printed Copy: US $155
Library License: US $516
ISSN: 2451-8743 (Print)
ISSN: 2214-5168 (Online)
ISBN: 978-1-60805-723-8 (Print)
ISBN: 978-1-60805-722-1 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080572211130101

Introduction

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.

Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimers Disease research.

Preface

- Pp. i-ii (2)
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List of Contributors

- Pp. iii-vi (4)
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Immunotherapy with Anti-Aβ Monoclonal Antibodies in Alzheimer’s Disease: A Critical Review on the Molecules in the Pipelines with Regulatory Considerations

- Pp. 3-85 (83)
Chrystelle Mavoungou, Katharina Schindowski Zimmerman
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The Development of Multi-Target-Directed Ligands (MTDL) to Treat Alzheimer’s Disease

- Pp. 86-108 (23)
John W. Wright, Joseph W. Harding
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Next Generation Drugs in Alzheimer's Disease Treatment: From Benchtop to Bedside

- Pp. 109-146 (38)
Rosaria A. Cavallaro, Andrea Fuso
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Tau-Directed Therapies for Alzheimer’s Disease and Other Tauopathies

- Pp. 147-182 (36)
Yasumasa Yoshiyama
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Different Approaches in the Treatment of Alzheimer's Disease: Comprehensive Insight

- Pp. 183-216 (34)
Zaciragic Asija
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Alzheimer’s Disease and Dementia: A Midlife Approach to Treatment is Needed

- Pp. 217-242 (26)
Angela Clifford, Jennifer Stock, Stephan Bandelow, Tri Budi Rahardjo, Eef Hogervorst
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Neurogenic Molecules Modulating Cell Survival Pathways, Amyloid Beta, Tau Proteins, and Metal Dyshomeostasis: An Alternative Hope for Alzheimer’s Therapy

- Pp. 243-264 (22)
Hailin Zheng, Mati Fridkin, Moussa B.H. Youdim
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Cognitive Decline and Alzheimer's Disease: A Central Role for Hypoxia-Obstructive Sleep Apnea and Related Stigmata in Elderly

- Pp. 265-314 (50)
Mak Adam Daulatzai
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Pharmacotherapies for Alzheimer’s Disease: From Natural Compounds to Target Synthetic Drugs

- Pp. 315-366 (52)
Chuang Wang, Rui Wang, James M. O’Donnell, Ying Xu
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Challenges in the Morphological Diagnosis of Dementias

- Pp. 367-410 (44)
Kurt A. Jellinger
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Metal Ions in the Pathogenesis of Alzheimer’s Disease: An Open Field

- Pp. 411-431 (21)
Guido Crisponi, Valeria M. Nurchi, Daniela Fanni, Clara Gerosa, Sonia Nemolato, Miriam Crespo-Alonso, Leonardo Toso, Joanna I. Lachowicz, Gavino Faa
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Index

- Pp. 432-456 (25)
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