Editors: Bashir M. Matata , Maqsood M. Elahi

The Molecular Basis for the Link between Maternal Health and the origin of Fetal Congenital Abnormalities: An Overview of Association with Oxidative Stress

eBook: US $49 Special Offer (PDF + Printed Copy): US $113
Printed Copy: US $89
Library License: US $196
ISBN: 978-1-60805-536-4 (Print)
ISBN: 978-1-60805-286-8 (Online)
Year of Publication: 2011
DOI: 10.2174/97816080528681110101

Introduction

This e-book discusses the molecular relationship between biological systems and risk factors for in-utero oxidative insults, maternal health and the impact on fetus at different critical developmental time windows (prenatal or even postnatal). Plausibly, prenatal and early postnatal periods are the most critical “windows” to oxidative stress programming insults. Pro-oxidative stress is a common feature of many conditions associated with adverse fetal growth and/or preterm birth, such as pre-eclampsia, diabetes, smoking, malnutrition or excessive nutrition, infection or inflammation. Oxidative stress insults may be directly linked to or associated with many genetic, nutritional and environmental risk factors that contribute to risks of adverse fetal growth or preterm birth. This e-book should be a valuable reference for medical researchers and working professionals interested in congenital defects.

Contributors

Editor(s):
Bashir M. Matata
Liverpool Heart & Chest Hospital NHS Foundation Trust
United Kingdom


Maqsood M. Elahi
Prince of Wales and Sydney Children Hospital
Australia




Contributor(s):
Maqsood M. Elahi
Cardiothoracic Surgeon
Department of Cardiothoracic Surgery
Prince of Wales and Sydney Children Hospital
Randwick
NSW
Australia


Bashir M. Matata
Director of Clinical Trials Unit/Lecturer (Hon)
Liverpool Heart & Chest Hospital NHS Foundation Trust
Liverpool
L14 3PE
United Kingdom


Pascalle Chavatte-Palmer
Assistant Professor
UMR INRA/ENVA/INA P-G 1198 biologie du développement et reproduction
78350 Jouy-en-Josas
France


Gunther Meinlschmidt
Full Professor, Department of Clinical Psychology and Psychotherapy
Faculty of Psychology University of Basel
Birmannsgasse 8
CH-4055 Basel
Switzerland


Hany Aly
Department of Newborn Services
The George Washington University and the Children’s National Medical Center
Washington
DC
USA


Kaoru Nagai
Assistant Professor, Department of Epigenetic Medicine
Interdisciplinary Graduate School of Medicine and Engineering
University of Yamanashi
Yamanashi , 409-3898
Japan


Angelica Mohn
Associate Professor, Departments of Pediatrics
University of Chieti
66100 Chieti
Italy


Luis Sobrevia
Associate Professor, Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstretics and Gynaecology
Medical Research Centre (CIM)
School of Medicine
Faculty of Medicine
Pontificia Universidad Catolica de Chile
Marcoleta 391
Santiago
Chile


Umberto Simeoni
Full Professor, Chair on Infancy
Environment and Health
The University Foundation
Université de la Méditerranée
Marseille
France


Dupont C
Service d’Histologie-Embryologie-Cytogenetique-Biologie de la Reproduction-CECOS
Hôpital Jean Verdier (AP-HP)
F-93143 Bondy
France


Levy R
Service d’Histologie-Embryologie-Cytogenetique-Biologie de la Reproduction-CECOS
Hôpital Jean Verdier (AP-HP)
F-93143 Bondy
France


Cordier AG
INRA, UMR 1198 Biologie du développement et reproduction
F-78350 Jouy en Josas
France


Junien C
INRA, UMR 1198 Biologie du développement et reproduction
F-78350 Jouy en Josas
France


Marion Tegethoff
Division of Clinical Psychology and Psychiatry
Department of Psychology
University of Basel
Switzerland


Tetyana H. Nesterenko
Department of Newborn Services
The George Washington University and the Children’s National Medical Center
Washington
DC
USA


Valentina Chiavaroli
Department of Pediatrics
University of Chieti
66013 Chieti
Italy


Francesco Chiarelli
Department of Pediatrics
University of Chieti
66013 Chieti
Italy


Marcelo González
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile


Ernesto Muñoz
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile


Carlos Puebla
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile


Enrique Guzmán-Gutiérrez
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile


Fredi Cifuentes
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile


Fernando Abarzúa
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile


Andrea Leiva
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile


Paola Casanello
Cellular and Molecular Physiology Laboratory (CMPL)
Division of Obstetrics and Gynecology
School of Medicine
Pontificia Universidad Católica de Chile
P.O. Box 114-D
Santiago
Chile




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