Editor: Anna Strunecka

Cellular and Molecular Biology of Autism Spectrum Disorders

eBook: US $91 Special Offer (PDF + Printed Copy): US $164
Printed Copy: US $119
Library License: US $364
ISBN: 978-1-60805-396-4 (Print)
ISBN: 978-1-60805-196-0 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080519601100101


Over the past several decades the incidence of autism spectrum disorders (ASD) has increased dramatically. The etiology of ASD remains an unsolved puzzle to scientists, physicians, pediatricians, psychiatrists, and pharmacologists. Our E-book will address what is presently known concerning the pathophysiology of ASD from a cellular and molecular perspective. Our explanation is based on the interaction between repetitive systemic immune stimulation with concomitant chronic brain activation of microglia, which leads to overstimulation of glutamate receptors and inflammatory cytokine receptors. Our E-book will explain, for the first time, the effects of immunoexcitotoxicity on the brain development, neurophysiology, and pathology. Our book will not only attempt to explain the finding in ASD, but will offer treatment proposals that address each of these mechanisms. It will also explain how previous, often successful treatment methods, may indeed operate through the immunoexcitotoxic mechanism.


Anna Strunecka
Charles University in Prague
Czech Republic

Russell L. Blaylock
Neurosurgeon. Institute for Theoretical Neuroscience
LLC and Visiting Professor of Biology, Belhaven University
MS, 39157

Mark Hyman
Chairman, Institute for Functional Medicine. Volunteer, Partners in Health Founder and Medical Director
45 Walker Street
MA, 01240

Ivo Paclt
Associated Professor in Psychiatry, Psychiatric Department, 1st Faculty of Medicine
Charles University in Prague
Czech Republic
Ke Karlovu 11, Prague 2, 128 00 Czech Republic. and Subdepartment of Postgradual Training Child and Adolescent Psychiatry, Institute for Postgraduate Medical Education,
Czech Republic

Anna Strunecka
Professor in Physiology, Department of Physiology, Faculty of Science
Charles University in Prague
Vinicna 7, 128 00
Czech Republic
nstitute of Medical Biochemistry, Laboratory of Neuropharmacology
1st Faculty of Medicine, Charles University in Prague
Albertov 4, Prague 2, 128 00 Czech Republic
Czech Republic


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