Editors: Akhlaq Farooqui , Tahira Farooqui

Molecular Aspects of Neurodegeneration and Neuroprotection

eBook: US $61 Special Offer (PDF + Printed Copy): US $140
Printed Copy: US $110
Library License: US $244
ISBN: 978-1-60805-376-6 (Print)
ISBN: 978-1-60805-092-5 (Online)
Year of Publication: 2011
DOI: 10.2174/97816080509251110101

Introduction

Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. For example, in Alzheimer disease, neuronal degeneration occurs in the nucleus basalis, whereas in Parkinson disease, neurons in the substantia nigra die. The most severely affected neurons in Huntington disease are striatal medium spiny neurons. The neuronal populations that are lost in neurodegenerative diseases modulate functions such as controlling movements, processing sensory information, memory, and making decisions. Although, the molecular mechanism of neurodegeneration remains unknown, but excitotoxicity, inflammation, and oxidative stress may contribute to neural cell demise independently or synergistically. The purpose of this E-book is to present readers with cutting edge and comprehensive information on molecular aspects of neurodegenerative diseases and neuroprotection in a manner that is useful not only to students and teachers, but also to researchers and physicians.

Contributors

Editor(s):
Akhlaq Farooqui
The Ohio State University
USA


Tahira Farooqui
The Ohio State University
USA




Contributor(s):
D. M. Bonifati
Department of Neurological disorders
Santa Chiara Hospital
Largo Medaglie d’Oro 1
Trento
Italy


T. Farooqui
Department Entomology/Center for Molecular Neurobiology
The Ohio State University, Columbus
Ohio
USA


S. Cardoso
Department of Zoology
Faculty of Sciences and Technology, University of Coimbra
Coimbra
Portugal


Y. Hirashima
Physiological Chemistry, Faculty of Pharmaceutical Sciences
Teikyo University, Sagamiko, Sagamihara
Kanagawa
Japan


S.C. Correia
Department of Zoology, Faculty of Sciences and Technology
University of Coimbra
Coimbra
Portugal


S.R. Joshi
Interactive Research School for Health Affairs
Bharati Vidyapeeth
Pune
India


C. Carvalho
Department of Zoology, Faculty of Sciences and Technology
University of Coimbra
Coimbra
Portugal


A. Kale
Interactive Research School for Health Affairs
Bharati Vidyapeeth
Pune
India


F. Coppedè
Department of Neuroscience
University of Pisa, Via Roma
Pisa
Italy


U. Kishore
Laboratory of Human Immunology and Infection Biology
Biosciences Division Brunel University
Uxbridge West London UB8 3PH
UK


U.N. Das
Jawaharlal Nehru Technological University
Kakinada, India and UND Life Sci, Shaker Heights
Ohio
USA


S.P. Mahadik
Department of Psychiatry and Health Behavior
Medical College of Georgia
Augusta
GA
USA


A.A. Farooqui
Department of Molecular and Cellular Biochemistry
The Ohio State University, Columbus
Ohio
USA


L. Migliore
Department of Human and Environmental Sciences
University of Pisa
Via S. Giuseppe 22
Pisa
Italy


P.I. Moreira
Institute of Physiology, Faculty of Medicine
University of Coimbra
Coimbra
Portugal


R.X. Santos
Department of Zoology,
Faculty of Sciences and Technology, University of Coimbra
Coimbra
Portugal


A. Nayak
Laboratory of Human Immunology and Infection Biology
Biosciences Division, Brunel University
Uxbridge West London UB8 3PH
UK


M.A. Smith
Department of Pathology
Case Western Reserve University, Cleveland
Ohio
USA


W.Y. Ong
Department of Anatomy
National University of Singapore
Singapore


L.J. Wallace
Division of Pharmacology
College of Pharmacy, The Ohio State University, Columbus
Ohio
USA


G Perry
UTSA Institute for Neuroscience and Department of Biology
College of Sciences, University of Texas,
San Antonio
Texas
USA


X. Zhu
Department of Pathology
Case Western Reserve University, Cleveland
Ohio
USA




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