Editor: Malay Chatterjee

Angiogenesis & Therapeutic Targets In Cancer

Personal Book: US $44 Special Offer (PDF + Printed Copy): US $140
Printed Copy: US $119
Library Book: US $176
ISBN: 978-1-60805-573-9
eISBN: 978-1-60805-007-9 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080500791100101

Introduction

Angiogenesis plays rate limiting roles in tumor growth and invasion. Angiogenesis inhibition has been proposed as a general strategy to fight against cancers. This book covers different therapeutic targets for angiogenesis interventions with emphasis on clinical development of antiangiogenic drugs that target antiangiogenic cascade in different forms of cancers like breast cancer, multiple myeloma, renal carcinoma, gastrointestinal, prostate and lung cancer. Surrogate predictive markers of antiangiogenic therapy in novel preclinical models recapitulating tumor microenvironment together with genomic studies are special features of this book. Gene therapy approaches with emphasis on viral vectors have been explored in preclinical model with direct and indirect angiogenesis inhibitors. Recent advances in clinical application with antiangiogenic therapy resulted in encouraging clinical results are also detailed. It includes chapters that bridge the gap between basic science and clinical application of current knowledge of cancer. Different chapters are contributed by distinguished scientists and clinicians around the world making it an important addition to the bookshelves of clinicians, academics, researchers, students and institutions.

Contributors

Editor(s):
Malay Chatterjee
Jadavpur University
India




Co-Editor(s):
Ajay Rana
Loyola University Medical Center
USA


Basabi Rana
Loyola University Medical Center
USA




Contributor(s):
Theodora Kerenidi
Respiratory Department
Thessaly School of Medicine
Magniton 32
Volos, 38333
Greece


Kostas Syrigos
Oncology Unit GPP, Athens School of Medicine
Greece


Wen W. Ma
Roswell Park Cancer Institute
Elm and Carlton Streets
Buffalo
NY , 14263
USA


Ellen Kossoff
Roswell Park Cancer Institute
Elm and Carlton Streets
Buffalo
NY , 14263
USA


Anupam Bishayee
Department of Pharmaceutical Sciences
Northeastern Ohio Universities Colleges of Medicine and Pharmacy
4209 State Route 44
Rootstown
OH, 44272
USA


Ana R. Quesada
Department of Molecular Biology and Biochemistry Faculty of Science
University of Málaga
and CIBER de Enfermedades Raras (CIBERER)
Málaga , 29071
Spain


Miguel Ángel Medina
Department of Molecular Biology and Biochemistry Faculty of Science
University of Málaga
and CIBER de Enfermedades Raras (CIBERER)
Málaga , 29071
Spain


Carmen Silvia Passos Lima
Clinical Oncology Service Department of Internal Medicine
Faculty of Medical Sciences, State University of Campinas
Campinas
SP
Brazil


Gustavo Jacob Lourenço
Department of Internal Medicine Faculty of Medical Sciences
State University of Campinas
Campinas
SP
Brazil


José Augusto Rinck
Department of Internal Medicine Faculty of Medical Sciences
State University of Campinas
Campinas
SP
Brazil


C. Oliver Hanemann
Clinical Neurobiology
Peninsula College of Medicine and Dentistry
The John Bull Building Tamar Science Park Research Way
Plymouth
PL6 8BU
UK


Sylwia Ammoun
Clinical Neurobiology
Peninsula College of Medicine and Dentistry
The John Bull Building Tamar Science Park Research Way
Plymouth
PL6 8BU
UK


Dr. Mai Har Sham
Department of Biochemistry,
Li Ka Shing Faculty of Medicine, The University of Hong Kong
21 Sassoon Road, Pokfulam
Hong Kong
SAR
China


Kexia Cai
Department of Biochemistry
Li Ka Shing Faculty of Medicine, The University of Hong Kong
21 Sassoon Road Pokfulam
Hong Kong
SAR
China


Oliver Stoeltzing
Departments of Hepatobiliary Surgery and Transplantation Surgery
University Medical Center Hamburg-Eppendorf Martinistr
Hamburg 52, 20246
Germany


C. Moser
Departments of Surgery and Surgical Oncology
University of Regensburg Medical Center
Regensburg, 93042
Germany


Pierfrancesco Tassone
Medical Oncology Unit and Center for Innovative Treatments in Medical Oncology
University “Magna Græcia” and Tommaso Campanella Cancer Center Viale Europa
Catanzaro, I-88100
Italy


Teresa Calimeri
Medical Oncology Unit and Center for Innovative Treatments in Medical Oncology
University “Magna Græcia” and Tommaso Campanella Cancer Center Viale Europa
Catanzaro , I-88100
Italy


Marco Rossi
Medical Oncology Unit and Center for Innovative Treatments in Medical Oncology
University “Magna Græcia” and Tommaso Campanella Cancer Center Viale Europa
Catanzaro, I-88100
Italy


Maria Teresa Di Martino
Medical Oncology Unit and Center for Innovative Treatments in Medical Oncology
University “Magna Græcia”and Tommaso Campanella Cancer Center Viale Europa
Catanzaro
I, 88100
Italy


Paola Neri
Medical Oncology Unit and Center for Innovative Treatments in Medical Oncology
University “Magna Græcia”and Tommaso Campanella Cancer Center Viale Europa
Catanzaro, I-88100
Italy
/
Department of Medicine Foothills Medical Center
University of Calgary
AB
Canada


G. Gasparini
Division of Medical Oncology ‘San Filippo Neri’ Hospital
Via Martinotti 20
Rome, 00135
Italy


R. Longo
Division of Medical Oncology ‘San Filippo Neri’ Hospital
Via Martinotti 20
Rome, 00135
Italy


Epie Boven
VU University medical center Department of Medical Oncology
De Boelelaan 1117
Amsterdam
HV , 1081
The Netherlands


Martijn R. Meijerink
VU University medical center Department of Radiology
De Boelelaan 1117
Amsterdam
HV , 1081
The Netherlands


Laura Vroling
VU University medical center Department of Medical Oncology
De Boelelaan 1117
Amsterdam
HV , 1081
The Netherlands


Astrid A.M. van der Veldt
VU University medical center Department of Medical Oncology
De Boelelaan 1117
Amsterdam
HV , 1081
The Netherlands


Natasha Kyprianou
Division of Urology
Combs Cancer Building Room, 306, University of Kentucky Medical Center
800, Rose Street
Lexington
KY , 40536



Joanne Collazo
Departments of Toxicology Urology/Surgery and Department of Molecular and Cellular Biochemistry College of Medicine
University of Kentucky College of Medicine and Markey Cancer Center
Combs Blg. Room 306 800 Rose Street
Lexington
KY, 40536
U.S.A


Stewart Martin
School of Molecular Medical Sciences
Division of Clinical Oncology University of Nottingham
Nottingham University Hospitals City Hospital Campus
Nottingham
NG5 1PB
UK


H. Evans
School of Molecular Medical Sciences
Division of Clinical Oncology University of Nottingham
Nottingham University Hospitals City Hospital Campus
Nottingham
NG5 1PB
UK




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