Editors: Ashutosh Kumar Dash, Deepak Kumar

The Role of Chromenes in Drug Discovery and Development

eBook: US $59 Special Offer (PDF + Printed Copy): US $95
Printed Copy: US $65
Library License: US $236
ISBN: 978-981-5124-34-7 (Print)
ISBN: 978-981-5124-33-0 (Online)
Year of Publication: 2023
DOI: 10.2174/9789815124330123010001

Introduction

Chromene is a naturally abundant heterocyclic compound found in alkaloids, tocopherols, terpenes and other compounds. Its derivatives can be used as a scaffold that exhibits pharmacological activity in the human body.

Chromene drugs and related bioactive molecules are the prime focus of this reference. It presents 13 thoroughly researched chapters that comprehensively cover all aspects about the molecule. Starting with a detailed introduction to its role and importance in drug discovery, the book goes into the details of chromene structure, synthesis and pharmacology. Readers can gain knowledge of different commercial medicines based on chromene and its pharmacological activity against different diseases. The elaborate topics in the book will help researchers working on chromene based drugs.

Key highlights of the book include:

- Complete coverage of chromene’s role in nature and drug development with references to historical background and current developments

- References to commercial and preclinical drugs and patents of interest

- Explanation of chromene bioacivity in different diseases (antioxidant, antidiabetic, antinflammatory, antibacterial and antifungal activities, antitumour, immunomodulatory activity)

- Explanation of chromene activity against SARS-Cov2

Contributors

Editor(s):
Ashutosh Kumar Dash
Department of Medicinal Chemistry
Devsynthesis India Pvt. Ltd.
Hyderabad, India


Deepak Kumar
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences, Shoolini University
Solan, 173229, India




Contributor(s):
Arti Devi
University Institute of Biotechnology
Chandigarh University
Mohali 140413
Punjab, India


Ashutosh Kumar Dash
Department of Medicinal Chemistry
Devsynthesis India Pvt. Ltd.
Hyderabad
India


Atul Kumar
Department of Chemistry and Chemical Sciences
Central University of Jammu, Rahya-Suchani (Bagla)
District-Samba, Jammu-181143
Jammu and Kashmir, India


Anuradha Mittal
University Institute of Biotechnology
Chandigarh University
Mohali 140413, Punjab
India


Aadesh Kumar
Department of Pharmaceutical Sciences
Sir J. C. Bose Technical Campus Bhimtal
Kumaun University, Nainital-263136
Uttarakhand, India


Ashish Dogra
Toxicology and Formulation Division
CSIR-Indian Institute of Integrative Medicine
Jammu, Jammu and Kashmir-180001
India


Ankit Kumar
Department of Pharmaceutical Sciences
Sir J. C. Bose Technical Campus Bhimtal
Kumaun University, Nainital-263136
Uttarakhand, India


Abhishek Gour
Academy of Scientific and Innovative Research (AcSIR)
Ghaziabad
Uttar Pradesh-201 002
India


Arun Kumar
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences
Shoolini University, Solan
Himachal Pradesh, India


Anchala Guglani
Department of Pharmaceutical Science
Bhimtal Campus, Kumaun University Nainital
Bhimtal, Uttarakhand
India


Amit Kumar Nigam
Goel Institute of Pharmacy and Sciences
Lucknow -226005
India
/
Faculty of Pharmacy, Amarpalli Instititute of Technology
Haldwani-263139, Uttarakhand
India


Biplab Kumar Dey
Faculty of Pharmaceutical Science
Assam Down Town University
Panikhaiti, Guwahati 781026, Assam
India


Deepak K. Sharma
Department of Pharmaceutical Engineering and Technology
Indian Institute of Technology, Banaras Hindu University
Varanasi-221005, U.P.
India


Diksha Rajput
Department of Chemistry and Chemical Sciences
Central University of Jammu, Rahya-Suchani (Bagla)
District-Samba, Jammu-181143
Jammu and Kashmir, India


Dheeraj Bisht
Department of Pharmaceutical Sciences
Sir J. C. Bose Technical Campus Bhimtal
Kumaun University, Nainital-263136
Uttarakhand, India


Dipti B. Ruikar
School of Pharmacy
G H Raisoni University
Amravati, Maharashtra
India


Debaraj Mukherjee
Natural Product Chemistry Division
Indian Institute of Integrative Medicine
Canal Road, Jammu 180001, Jammu and Kashmir
India


Deepak Kumar
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences
Shoolini University, Solan
Himachal Pradesh, India


Deepak Sati
Department of Pharmaceutical Sciences
Sir J. C. Bose Technical Campus Bhimtal, Kumaun University
Nainital-263136, Uttarakhand
India


Deepak Kumar Jindal
Department of Pharmaceutical Sciences
Guru Jambheshwar University of Science & Technology
Hisar (Haryana)-125001
India


Faruk Alam
Faculty of Pharmaceutical Science
Assam Down Town University
Panikhaiti, Guwahati 781026, Assam
India


Gowsia Jan
Department of Chemistry and Chemical Sciences
Central University of Jammu, Rahya-Suchani (Bagla)
District-Samba, Jammu-181143
Jammu and Kashmir, India


Gajanan J. Deshmukh
Department of Pharmacy
Government Polytechnic
Amravati
Maharashtra, India


Harish K. Indurthi
Department of Pharmaceutical Engineering and Technology
Indian Institute of Technology, Banaras Hindu University
Varanasi-221005, U.P.
India


Harleen Kaur Walia
Department of Biotechnology
Thapar Institute of Engineering and Technology
Patiala
Punjab, India


Harmandeep Kaur Gulati
Department of Pharmaceutical Sciences
Guru Nanak Dev University
Amritsar, 143005
India


Isha Dhamija
Department of Pharmaceutical Sciences
Guru Jambheshwar University of Science & Technology
Hisar (Haryana)-125001
India


Jitender Singh
School of Pharmaceutical Sciences
IEC University
Solan, Himachal Pradesh
India


Jasha Momo H. Anál
Natural Product Chemistry Division
Indian Institute of Integrative Medicine
Canal Road, Jammu 180001, Jammu and Kashmir
India


Kamal Dua
Discipline of Pharmacy, Graduate School of Health
University of Technology Sydney
NSW 2007
Australia


Krittika Mukherjee
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences, Shoolini University
Solan, Himachal Pradesh
India


Karan Joshi
Faculty of Pharmacy
Kalabhavan Campus, The Maharaja Sayajirao University of Baroda
Vadodara 390 001, Gujarat
India


Monu Kumar Shukla
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences, Shoolini University, Solan
Himachal Pradesh
India


Mahesh Rachamalla
Department of Biology
University of Saskatchewan
Saskatoon
Canada


Mohmmad Rashid
Department of Pharmaceutical Chemistry and Pharmacognosy
College of Dentistry and Pharmacy, Buraydah Colleges
Buraydah, Al-Qassim 31717
Saudi Arabia


Nitin Verma
School of Pharmacy
Chitkara University
Himachal Pradesh
India


Niraj Kumar Jha
Department of Biotechnology
School of Engineering & Technology (SET), Sharda University
Greater Noida, Uttar Pradesh
201310, India


Parul Grover
KIET School of Pharmacy
KIET Group of Institutions
Delhi-NCR, Ghaziabad
201206, India


Parul Sood
School of Pharmacy
Chitkara University
Himachal Pradesh
India


Pulkit Asati
Department of Pharmaceutical Engineering and Technology
Indian Institute of Technology, Banaras Hindu University
Varanasi-221005, U.P.
India


Preeti K. Suresh
University Institute of Pharmacy
Pt. Ravishankar Shukla University
Raipur, Chhattisgarh, 492010
India


Paola Andrea Duran Cuevas
Scientific and Technological Bioresearch Nucleus
Universidad de la Frontera
Temuco
Brazil


Prashant R. Murumkar
Faculty of Pharmacy
Kalabhavan Campus, The Maharaja Sayajirao University of Baroda
Vadodara 390 001, Gujarat
India


Partha Pratim Dutta
Faculty of Pharmaceutical Science
Assam Down Town University
Panikhaiti, Guwahati 781026, Assam
India


Rajeshwar Kamal Kant Arya
Department of Pharmaceutical Science
Bhimtal Campus, Kumaun University Nainital
Bhimtal, Uttarakhand
India
/
Department of Pharmaceutical Sciences
Sir J. C. Bose Technical Campus Bhimtal
Kumaun University, Nainital-263136
Uttarakhand, India


Rasana Yadav
Faculty of Pharmacy
Kalabhavan Campus, The Maharaja Sayajirao University of Baroda
Vadodara 390 001, Gujarat
India


Rajeev K. Tonk
Department of Pharmaceutical Sciences
Delhi Pharmaceutical Sciences and Research University
Mehrauli, New Delhi 110017, Delhi
India


Sahil Jain
University Institute of Biotechnology
Chandigarh University
Mohali 140413
Punjab, India


Samarpita Das
Department of Pharmaceutical Engineering and Technology
Indian Institute of Technology, Banaras Hindu University
Varanasi-221005, U.P.
India


Shweta Ramkar
University Institute of Pharmacy
Pt. Ravishankar Shukla University
Raipur, Chhattisgarh, 492010
India


Santosh Kumar Rath
Department of Pharmaceutical Chemistry
Danteswari College of Pharmacy
Borpadar, Jagdalpur
Chhattisgarh 494221, India


Snehal Manekar
School of Pharmacy
G H Raisoni University
Amravati
Maharashtra, India


Sandeep Kumar
Department of Regulatory Affairs
National Institute of Pharmaceutical Education and Research
Hyderabad (Telangana)-500037
India


Utpal Nandi
Toxicology and Formulation Division
CSIR-Indian Institute of Integrative Medicine
Jammu, Jammu and Kashmir-180001
India


Vellaisamy Sridharan
Department of Chemistry and Chemical Sciences
Central University of Jammu, Rahya-Suchani (Bagla)
District-Samba, Jammu-181143
Jammu and Kashmir, India


Vagish Dwibedi
University Institute of Biotechnology
Chandigarh University
Mohali 140413
Punjab, India


Vivek Panwar
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences
Shoolini University, Solan (H.P)-173229
India




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