Editor: Zareen Amtul

Frontiers in Clinical Drug Research - CNS and Neurological Disorders

Volume 11

eBook: US $89 Special Offer (PDF + Printed Copy): US $142
Printed Copy: US $98
Library License: US $356
ISSN: 2451-8883 (Print)
ISSN: 2214-7527 (Online)
ISBN: 978-981-5123-32-6 (Print)
ISBN: 978-981-5123-31-9 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151233191231101


Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology.

The eleventh volume of this series features reviews that cover the following topics related to the treatment of a variety of CNS disorders, related diseases, and basic research:

- The Multi-target Directed Ligands candidate (MTDLs) prototypes for neurodegenerative diseases

- Drugs for relapse prevention in addiction

- Neuroprotective activities of cinnamic acids and their derivatives in neurodegenerative disorders

- Phytosome for targeted delivery of natural compounds in treating alzheimer's disease

- Physical activity as a non-pharmacologic method for treatment of alzheimer’s disease


Pharmaceutical scientists, clinical researchers, medical consultants and allied healthcare professionals interested in neuropharmacology and neurology.


- Pp. i
Zareen Amtul*
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List of Contributors

- Pp. ii-iii (2)

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Multi-functional Ligands and Molecular Hybridization: Conceptual Aspects and Application in the Innovative Design of Drug Candidate Prototypes for Neurodegenerative Diseases

- Pp. 1-157 (157)
Matheus de Freitas Silva, Flávia Pereira Dias Viegas, Vanessa Silva Gontijo, Cindy Juliet Cristancho Ortiz, Graziella dos Reis Rosa Franco, Januário Tomás Ernesto, Caio Miranda Damásio, Gabriel Pinto da Silva Fonseca, Isabela Marie Fernandes Silva, Larissa Emika Massuda, Maria Fernanda da Silva, Thâmara Gaspar Campos Thâmara Gaspar Campos, Priscila da Mota Braga, Claudio Viegas*
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Drugs For Relapse Prevention in Addiction: Review of Psychological and Neurological Factors, Genetics and Neurobiological Mechanisms

- Pp. 158-237 (80)
Cheng Hua*
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Neuroprotective Activities of Cinnamic Acids and their Derivatives

- Pp. 238-261 (24)
Pronit Biswas*, Rajesh Singh Yadav, Juli Jain
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Phytosome for Targeted Delivery of Natural Compounds: Improving Efficacy, Bioavailability, and Delivery across BBB for the Treatment of Alzheimer's Disease

- Pp. 262-282 (21)
Prashant Tiwari*, Geetha KM, Shweta Shrivastava, Yogita Kumari, Rajni Kant Panik, Pankaj Kumar Singh, Dileep Kumar, Pratap Kumar Sahu
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Alzheimer’s Disease and Physical Activity, Will the Symptoms Improve?

- Pp. 283-313 (31)
Maryam Hamzeloo-Moghadam*
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Subject Index

- Pp. 314-327 (14)
Zareen Amtul*
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.Frontiers in Clinical Drug Research - CNS and Neurological Disorders.
.Neurodegenerative Diseases: Multifactorial Degenerative Processes, Biomarkers and Therapeutic Approaches.
.Frontiers in Clinical Drug Research - CNS and Neurological Disorders.