Editor: Balkrishna Acharya

Therapeutic Drug Targets and Phytomedicine For Triple Negative Breast Cancer

eBook: US $59 Special Offer (PDF + Printed Copy): US $94
Printed Copy: US $65
Library License: US $236
ISBN: 978-981-5079-79-1 (Print)
ISBN: 978-981-5079-78-4 (Online)
Year of Publication: 2023
DOI: 10.2174/97898150797841230101


Triple negative breast cancers (TNBC) are a biologically aggressive form of breast cancer and constitute approximately 10-15% of all breast cancer patients. Distant metastasis, lack of clinically targeted therapies and prognostic markers, makes the disease difficult to treat. Till now not much work has been carried out on this deadly disease.

This book provides an overview of TNBC etiology, its treatment strategies and prognostic markers to identify the outcome of standard therapies. Signalling pathways namely cell proliferation, angiogenesis, invasion and metastasis, apoptosis, autophagy and others involved in complicating the disease have been described in the chapters to convey an understanding about the disease mechanisms. All the possible drugs either in pre-clinical or clinical stages have also been mentioned with data that depicts their efficiency in targeting altered genes. The book also introduces the reader to herbal medicine exhibiting high potency to target TNBC, their synthetic analogs used during chemotherapy and their ability to fight against chemoresistance. The concept of phytonanotechnology has also been discussed. The book helps create awareness among a broad range of readers about TNBC. It points to prioritizing the upgradation of health care facilities and re-designing future treatment strategies to provide maximum benefit to breast cancer patients.


A wide spectrum of readers especially those working in the field of breast cancer medicine, herbal medicine, traditional medicine and basic medical research.


Conventional drug therapies have greatly deteriorated the health of diseased individuals. Triple negative breast cancer is an aggressive form of breast cancer has led to mortality issues worldwide. Till now, no FDA-approved drugs are available in this regard. I certainly believe that herbal medicine can potentially revitalize human health affected due to triple negative breast cancer. Dietary intake of herbal products inadequate quantity may help in the prevention and treatment of disease. Herbal medicine may act as both preventive and therapeutic measures against the disease. In this regard, I would like to congratulate Acharya Balkrishna for designing this phenomenal piece of work to enlighten and enhance our understanding of TNBC. To create awareness amongst the diseased individuals & researchers, the present book would be of great help that will provide an overview of etiology, its treatment strategies, and prognostic marker to identify the outcome of standard therapies. In this book, herbal medicine exhibiting high potency to target TNBC has been enlightened to avoid the side effects associated with synthetic analogs used during chemotherapy, and also their ability to fight against chemoresistance was also represented. The proposed book will be of great importance for the wide spectrum of readers especially those working in the field of breast cancer, herbal medicine, traditional medicine, etc. The present piece of work will surely provide valuable hints to discover novel therapeutic regimens to fight against other cancers also. It will act as reference material as well for research scholars and both graduate & post-graduate students to explore novel therapeutic regimens against the disease without affecting the health of affected individuals.

Swami Ramdev
Founder of Patanjali Yogpeeth Trust