Editor: Balkrishna Acharya

Therapeutic Drug Targets and Phytomedicine For Triple Negative Breast Cancer

eBook: US $59 Special Offer (PDF + Printed Copy): US $101
Printed Copy: US $71
Library License: US $236
ISBN: 978-981-5079-79-1 (Print)
ISBN: 978-981-5079-78-4 (Online)
Year of Publication: 2023
DOI: 10.2174/97898150797841230101

Introduction

Triple negative breast cancers (TNBC) are a biologically aggressive form of breast cancer and constitute approximately 10-15% of all breast cancer patients. Distant metastasis, lack of clinically targeted therapies and prognostic markers, makes the disease difficult to treat. Till now not much work has been carried out on this deadly disease.

This book provides an overview of TNBC etiology, its treatment strategies and prognostic markers to identify the outcome of standard therapies. Signalling pathways namely cell proliferation, angiogenesis, invasion and metastasis, apoptosis, autophagy and others involved in complicating the disease have been described in the chapters to convey an understanding about the disease mechanisms. All the possible drugs either in pre-clinical or clinical stages have also been mentioned with data that depicts their efficiency in targeting altered genes. The book also introduces the reader to herbal medicine exhibiting high potency to target TNBC, their synthetic analogs used during chemotherapy and their ability to fight against chemoresistance. The concept of phytonanotechnology has also been discussed. The book helps create awareness among a broad range of readers about TNBC. It points to prioritizing the upgradation of health care facilities and re-designing future treatment strategies to provide maximum benefit to breast cancer patients.

Audience

A wide spectrum of readers especially those working in the field of breast cancer medicine, herbal medicine, traditional medicine and basic medical research.

Contributors

Editor(s):
Balkrishna Acharya
Vice-Chancellor
University of Patanjali
Haridwar
India
/
Chief Secretary, Patanjali Research Foundation Trust
Haridwar
India
/
Board of Director, PYP Yog Foundation
INC, NFP
US
/
Trustee, Patanjali Yog Peeth Trust, 40 Lambhill Street
Kinning Park, Glasgow, G41 1AU
United Kingdom




Contributor(s):
Acharya Balkrishna
Patanjali Herbal Research Department
Patanjali Research Institute
Haridwar
India


Aminu Abubakar
Nigerian Institute For Trypanosomiasis And Onchocerciasis Research Kano State Liaison Office
Bayero University Kano
Gwarzo Road
Nigeria


Amitha Muraleedharan
Faculty of Health Sciences
Ben-Gurion University of the Negev
Beer Sheva
Israel


Ankit Gupta
University of Tasmania
Liverpool Street, Hobart
Tasmania
Australia


Balachandran S. Vinod
Department of Biochemistry
Sree Narayana College
Kollam
India


Haritha H Nair
Cancer Research Program, Division of Cancer Research, Thiruvanantha-puram
Rajiv Gandhi Centre for Biotechnology
Kerala
India


Nikhil Ponnoor Anto
The Shraga Segal Dept. of Microbiology, Immunology & Genetics, Faculty of Health Science
Ben-Gurion University of the Negev
Beer Sheva 84105
Israel


Rashmi Mittal
Patanjali Herbal Research Department
Patanjali Research Institute
Haridwar
India


Rohit Saxena
Biorefinery Group, Food Research Department, Faculty of Chemistry Sciences Autonomous
University of Coahuila
Saltillo, Coahuila
Mexico


Ruby John Anto
Cancer Research Program, Division of Cancer Research, Thiruvanantha-puram
Rajiv Gandhi Centre for Biotechnology
Kerala
India


Sagar Kumar
Patanjali Herbal Research Department
Patanjali Research Institute
Haridwar
India


Saima Kauser Nasir
Bio-imaging facility, Department of Microbiology and Cell Biology (MCB), Division of Biological sciences
Indian Institute of Science Bangalore
Karnataka
Indian


Smitha V. Bava
Department of Biotechnology
University of Calicut
Malappuram
India


Sreekumar Usha Devi Aiswarya
Department of Biotechnology
University of Calicut
Malappuram
India


Usman Umar Zango
Department of Biology
Sa'adatu Rimi College of Education
Kumbotso, Kano State
Nigeria


Vedpriya Arya
Patanjali Herbal Research Department
Patanjali Research Institute
Haridwar
India


Vikrant Singh
Department of Surgery
Royal College of Surgeons
York Street, Dublin
Ireland


Vipin Kumar Singh
Department of International Relations
Indian Institute of Technology
Roorkee
India