Editors: Rupesh K. Gautam, Lokesh Deb, Kamal Dua

Series Title: Frontiers in Arthritis

Natural Products for the Management of Arthritic Disorders

Volume 5

eBook: US $69 Special Offer (PDF + Printed Copy): US $126
Printed Copy: US $91
Library License: US $276
ISSN: 2468-6662 (Print)
ISSN: 2468-6670 (Online)
ISBN: 978-981-5050-78-3 (Print)
ISBN: 978-981-5050-77-6 (Online)
Year of Publication: 2022
DOI: 10.2174/97898150507761220101

Introduction

Rheumatoid arthritis (RA) is the most common inflammatory complication and affects approximately 1 % of the global population. It affects three times more women than men. RA is an autoimmune disorder elicited by exposure of genetic factors from the host to unknown antigens causing arthritogenic complaints. It also includes the activation of lymphocytes as well as CD4+ helper T cells along with the local release of chronic inflammatory mediators and cytokines like tumor necrosis factor (TNF‐α) and various cytokines like interleukins (IL) that enormously affect the joints. The available allopathic therapies for RA are not a cure for the complications, and antibody therapy and surgical procedures are expensive.

However, in the present era, researchers and healthcare professionals have moved toward natural medicines obtained from plants and other natural sources. Research-based on developments in phytomedicine has progressed steadily. Evidence has been collected to show the massive therapeutic potential of medicinal plants used in various traditional systems against many pathological complications. Researchers have focused on the therapeutic potential of natural products used for treatment and counteracting various disorders along with their complications having negligible adverse effects.

Natural Products for the Management of Arthritic Disorders compiles current knowledge about the bioactive compounds and herbal formulations useful in the treatment of rheumatoid arthritis. 11 chapters explain the role of natural products in the management of rheumatoid arthritis. Topics have been contributed by experts in medicinal chemistry and rheumatology.

The book first introduces the reader to rheumatoid arthritis before delving into conventional and alternative therapies for the disease. The editors have also included special topics such as the biomarkers for RA, cytokines and anti-inflammatory mediators, and preclinical and clinical studies. The range of topics should provide a comprehensive overview of natural remedies for arthritis and the role of natural products in anti-arthritic drug development.

The information will be useful for many readers including medical and pharmacology students, multidisciplinary research scholars, scientists, pharma/herbal/food industrialists, and policymakers.

Audience: Medical and pharmacology students, multidisciplinary research scholars, scientists, pharma/herbal/food industrialists, and policymakers.

Contributors

Editor(s):
Rupesh K. Gautam
Department of Pharmacology
MM School of Pharmacy
Maharishi Markandeshwar University
Ambala-Chandigarh Highway
Sadopur- Ambala-134007 (Haryana)
India


Lokesh Deb
Institute of Bioresources and Sustainable Development (IBSD) – Regional Centre Sikkim
Department of Biotechnology, Ministry of Science & Technology, Government of India
Tadong, Gangtok -737102
East Sikkim, Sikkim
India


Kamal Dua
Discipline of Pharmacy Graduate School of Health
Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine (ARCCIM)
University of Technology Sydney
Sydney
Australia




Contributor(s):
Ajeya Samanta
Eminent College of Pharmaceutical Technology Barasat
Kolkata-700126, West Bengal
India


Akshay M. Baheti
School of Pharmacy
Dr. Vishwanath Karad MIT World Peace University
Kothrud, Pune-411038
India


Aman Upaganlawar
SNJBs SSDJ College of Pharmacy
Chandwad, Nashik-423101
India


Amber Vyas
Department of Pharmacy
University Institute of Pharmacy, Pt. Ravishankar Shukla University
Raipur (C.G.)
India


Anil T. Pawar
School of Pharmacy
Dr. Vishwanath Karad MIT World Peace University
Kothrud, Pune-411038
India


Anjoo Kamboj
Chandigarh College of Pharmacy
Landran, Mohali, Punjab
India


Chiranjib Bhattacharjee
Department of Pharmacology
Srikrupa Institute of Pharmaceutical Sciences
Siddipet, 502277
India


Dhruba Bhattacharya
School of Environmental Studies
Jadavpur University
Kolata-700032, West Bengal
India


Diptendu Bhowmik
Department of Pharmacology
Srikrupa Institute of Pharmaceutical Sciences
Siddipet, 502277
India


Disha Arora
Himalayan Institute of Pharmacy
Kala amb, Distt. Sirmour, Himachal Pradesh, 173030
India


Hitesh Malhotra
Guru Gobind Singh College of Pharmacy
Yamuna Nagar, Haryana
India


Kamalika Mazumder
BCDA College of Pharmacy & Technology Hridaypur
Barasat, Kolkata-700127, West Bengal
India


Kaushik Biswas
Eminent College of Pharmaceutical Technology Barasat
Kolkata-700126, West Bengal
India


Lakshmi Kavuri
Research and Development Laboratory
Noble Pharma LLC
Menomonie, WI
USA


Pallavi Adate-More
School of Pharmacy
Dr. Vishwanath Karad MIT World Peace University
Kothrud, Pune-411038
India


Peeyush Kaushik
Guru Gobind Singh College of Pharmacy
Yamuna Nagar, Haryana
India


Randhir Singh
Department of Pharmacology
Central University of Punjab
Bhatinda, Punjab
India


Ravindra Kumar Pandey
Department of Pharmacognosy
Columbia Institute of Pharmacy
Raipur (C.G.)
India


Sahdeo Prasad
Research and Development Laboratory
Noble Pharma LLC
Menomonie, WI
USA


Sanjay Sharma
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management
SVKM's NMIMS Deemed to be University
Vile Parle West, Mumbai, Maharashtra-4000563
India


Sarath Nalla
Analytical Department
Alcami
Wilmington, NC 28405 NC
USA


Shiv Shankar Shukla
Department of Pharmaceutical Analysis and Quality Assurance
Columbia Institute of Pharmacy
Raipur (C.G.)
India


Shreyans Kumar Jain
Department of Pharmaceutical Engineering& Technology
IIT-BHU
Banaras- 221005, Uttar Pradesh
India


Subba Rao Chamakuri
Department of Pharmacognosy
Vaageswari College of Pharmacy
Karimnagar,Telangana, 505527
India


Subhash Chandra Chaturvedi
Sri Aurobindo Institute of Pharmacy
Indore
India


Sudha Vengurlekar
Sri Aurobindo Institute of Pharmacy
Indore
India


Sumeet Gupta
MM College of Pharmacy
Maharishi Markandeshwar (Deemed To Be University)
Mullana-Ambala (Haryana), 133207
India


Venu Kola
Department of Pharmacology
Srikrupa Institute of Pharmaceutical Sciences
Siddipet, 502277
India


Vijetha Pendyala
Department of Pharmacognosy and Phytochemistry
Chebrolu Hanumaiah Institute of Pharmaceutical Sciences
Guntur
India


Vikash Sharma
Department of Pharmacology
Anand College of Pharmacy
Agra (U.P.)
India