Editors: Atta-ur-Rahman , M. Iqbal Choudhary, Syed Ghulam Musharraf

Applications of Modern Mass Spectrometry

Volume 1

eBook: US $99 Special Offer (PDF + Printed Copy): US $168.5
Printed Copy: US $119
Library License: US $396
ISSN: 2717-6029 (Print)
ISSN: 2717-6037 (Online)
ISBN: 978-981-14-3380-1 (Print)
ISBN: 978-981-14-3382-5 (Online)
Year of Publication: 2020
DOI: 10.2174/97898114338251200101


Applications of Modern Mass Spectrometry covers the latest advances in the use of mass spectrometry in scientific research. The series attempts to present readers information on the broad range of mass spectrometry techniques and configurations, data analysis and practical applications. Each volume contains contributions from eminent researchers who present their findings in an easy to read format. The multidisciplinary nature of the works presented in each volume of this book series make it a valuable reference on mass spectrometry to academic researchers and industrial R&D specialists in applied sciences, biochemistry, life sciences and allied fields.

The first volume of the series presents 5 reviews:

- Applications of mass spectrometry for the determination of the microbial crude protein synthesis in ruminants

- Qualitative and quantitative LC-MS analysis in food proteins and peptides

- Chemometrics as a powerful and complementary tool for mass spectrometry applications in life sciences

- Recent developments of allied techniques of qualitative analysis of heavy metal ions in aqueous solutions with special reference to modern mass spectrometry

- New techniques and methods in explosive analysis


Mass spectrometry, combined with the modern tools of chemo- and bioinformatics, has emerged as one of the most powerful tools in research with numerous applications in industry. The analytical capacity of mass spectrometry has exceeded beyond its conventional role of determination molecular mass and structural determination. Recent developments in ionization, detection techniques and data analysis tools, as well as applications of mass spectrometry in various fields continue to open up new vistas in this rapidly evolving field. The present volume of “Application of Mass Spectrometry” provides a useful insight into some of these developments. The present 1st volume of this book series comprises of 5 comprehensive reviews, written by the leading practitioners of mass spectrometry. These articles present diverse applications of mass spectrometry in fields such as animal nutrition, food and environmental analysis, biomedical and forensic sciences, as well as toxicology and explosives. Qualitative and quantitative analysis and identification of proteins and peptides are the cross cutting themes in many of these articles.

The review by Gonzalez-Ronquillo et al. focuses on the accurate quantification of microbial protein synthesis in ruminants by employing 15N isotopic mass spectrometry. Zhu et al. review the recent developments in qualitative and quantitative analysis of proteins and peptides in food matrices through LC-MS techniques. Izadmanesh and Ghasemi have provided an extensive review of the use of chemometric tools for the analysis of complex mass spectrometric data. Heavy metal toxicity is a global health challenge, and reliable methods are required for the detection of heavy metals in water and other samples. Developments in this area employing ICP-MS methods are reviewed by Boruah and Biswas. Finally Anilanmert and Cengiz have reviewed the relevant literature on the direct and on-site detection of various explosives and their residues by modern mass spectrometry. Each article presents case studies of the use of various innovative mass spectrometric tools, along with their strengths and limitations.

We are grateful to all the authors for their excellent scholarly contributions, and for the timely submissions of their review article. We would also like to express our gratitude to Ms. Fariya Zulfiqar (Manager Publications) and Mr. Mahmood Alam (Director Publications) of Bentham Science Publishers for the timely completion of the volume in hand. We sincerely hope that the efforts of authors and production team will help readers in better understanding and appreciating the versatility and robustness of mass spectrometry, and motivate them to conduct good quality research and development work in this exciting area.

Prof. Atta-ur-Rahman, FRS
Kings College
University of Cambridge

Prof. M. Iqbal Choudhary
H.E.J. Research Institute of Chemistry
University of Karachi

Prof. Syed Ghulam Musharraf
H.E.J. Research Institute of Chemistry
University of Karachi


.Indicator Displacement Assays (IDAs): An Innovative Molecular Sensing Approach.
.Recent Advances in Analytical Techniques.
.Applications of NMR Spectroscopy.
.Advanced Techniques of Analytical Chemistry.