Editors: Shankar Suman, Shivam Priya, Akanksha Nigam

Breast Cancer: Current Trends in Molecular Research

eBook: US $79 Special Offer (PDF + Printed Copy): US $136
Printed Copy: US $96
Library License: US $316
ISBN: 978-1-68108-953-9 (Print)
ISBN: 978-1-68108-952-2 (Online)
Year of Publication: 2022
DOI: 10.2174/97816810895221120101


Breast cancer is one of the most common cancer types worldwide, and is a leading cause of cancer related deaths in women. In this book, medical experts review our current understanding of the molecular biology and characteristics of breast cancer. The topics covered in this book provide comprehensive knowledge of mechanisms underlying breast carcinogenesis, and are intended for a wide audience including scientists, teachers, and students.

11 chapters present information about several topics on breast cancer, including the role of cell growth and proliferation pathways, androgen and cytokine signaling, germline mutations in breast cancer susceptibility genes, and molecular factors causing invasive and metastatic breast cancer. In addition, the editors discuss the recent advancements in multi-omics data analysis based on inter-and intra-tumor molecular profiles.

The reference highlights how the knowledge and understanding of the biological behavior of breast neoplasms have facilitated ongoing investigations into dietary polyphenolic compounds with antioxidant properties, making them function as cancer chemopreventive agents. Along with this, the current development of treatment strategies such as targeted molecular therapy, and radiation therapy is brought to the fore to update readers.


Breast cancer malignancy is now becoming a global leading cause of cancer related death among females all around the world. The current developments in breast cancer research have wrought to increase the life expectancy in patients in the 21st century but a long way to go to cure this deadly disease. Among the major challenges, the heterogeneity in cancer cells make the disease more complex. Researchers have made a significant advancement in studying the heterogeneous features in breast cancer and multiple subsets of breast cancer are discovered. In the molecular biology studies, breast cancer stem-like cells, driver mutations and changes in tumor microenvironment are investigated as potentially hallmarks for the disease progression. Immunological aspects in breast cancer are considered cutting-edge science in recent discoveries. I am happy to look at this book that has incorporated all current advances in the breast cancer research. I congratulate Drs. Suman and Priya for editing a nice compilation of the different pieces of findings of breast cancer research in this book. I hope this will help to understand the recent advances in breast cancer to the researchers’ particularly new investigators and clinicians.

Chandan Singh, PhD
Assistant Professor, Department of Biochemistry
Banaras Hindu University