Editors: Shankar Suman, Shivam Priya, Akanksha Nigam

Breast Cancer: Current Trends in Molecular Research

eBook: US $79 Special Offer (PDF + Printed Copy): US $126
Printed Copy: US $87
Library License: US $316
ISBN: 978-1-68108-953-9 (Print)
ISBN: 978-1-68108-952-2 (Online)
Year of Publication: 2022
DOI: 10.2174/97816810895221120101


Breast cancer is one of the most common cancer types worldwide, and is a leading cause of cancer related deaths in women. In this book, medical experts review our current understanding of the molecular biology and characteristics of breast cancer. The topics covered in this book provide comprehensive knowledge of mechanisms underlying breast carcinogenesis, and are intended for a wide audience including scientists, teachers, and students.

11 chapters present information about several topics on breast cancer, including the role of cell growth and proliferation pathways, androgen and cytokine signaling, germline mutations in breast cancer susceptibility genes, and molecular factors causing invasive and metastatic breast cancer. In addition, the editors discuss the recent advancements in multi-omics data analysis based on inter-and intra-tumor molecular profiles.

The reference highlights how the knowledge and understanding of the biological behavior of breast neoplasms have facilitated ongoing investigations into dietary polyphenolic compounds with antioxidant properties, making them function as cancer chemopreventive agents. Along with this, the current development of treatment strategies such as targeted molecular therapy, and radiation therapy is brought to the fore to update readers.


- Pp. i
Chandan Singh
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- Pp. ii
Shankar Suman, Shivam Priya, Akanksha Nigam
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List of Contributors

- Pp. iii-iv (2)

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Cellular and Molecular Mechanisms of Breast Cancer Progression

- Pp. 1-21 (21)
Ajeet Kumar Verma*, Sanjay Mishra, Puja Rani Mina, Swati Misri
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Immune-Endocrine Perspectives of Breast Cancer

- Pp. 22-61 (40)
Karan Singh Saini*, Shankar Suman, Rituraj Konwar
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DNA Damage Response: A Therapeutic Landscape For Breast Cancer Treatment

- Pp. 62-85 (24)
Deepika Singh, Chandra Bhushan Prasad*
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Emerging Trends in Bioinformatics for Breast Cancer Molecular Research

- Pp. 86-108 (23)
Sammed N. Mandape*
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Role of Nitric Oxide in Breast Cancer

- Pp. 109-128 (20)
Ekhlaque A. Khan*, Akhtar Parwez
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Autoantibodies as Clinical Biomarkers in Breast Cancer

- Pp. 129-138 (10)
Prachi Gupta*
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Epigenetics of Breast Cancer

- Pp. 139-170 (32)
Manuraj Pandey*, Archana Lalwani, Rajendra Mehta
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Nanoparticles Targeting and Uptake: Current Advances in Breast Cancer Research

- Pp. 171-195 (25)
Onila Lugun, Alok Kumar Pandey*
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Dietary Polyphenols and its Molecular Mechanism in the Management of Breast Cancer

- Pp. 196-218 (23)
Girish Rai*, Sudhir Kumar Shekhar
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Radiotherapy in Carcinoma Breast

- Pp. 219-241 (23)
Teerthraj Verma*, Mranalini Verma, Ratnasekhar Ch
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An Overview of Breast Cancer Therapy

- Pp. 242-258 (17)
Alkhansa S. Mahmoud, Zuki AB. Zakaria, Hazilawati HJ. Hamzah, Tengku Ahbrizal F.T.A.*
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Subject Index

- Pp. 259-272 (14)
Shankar Suman, Shivam Priya, Akanksha Nigam
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