Editor: Touqeer Ahmed

Biochemical Mechanisms of Aluminium Induced Neurological Disorders

eBook: US $59 Special Offer (PDF + Printed Copy): US $108
Printed Copy: US $78
Library License: US $236
ISBN: 978-1-68108-884-6 (Print)
ISBN: 978-1-68108-883-9 (Online)
Year of Publication: 2021
DOI: 10.2174/97816810888391210101

Introduction

Aluminium is a chemical element present in earth’s crust and it is a known environmental toxin which has been found to be associated with various neurological disorders. Aluminium has been found to be a very strong risk factor for the development of Alzheimer’s disease.

Biochemical Mechanisms of Aluminium Induced Neurological Disorders explains the association of aluminium with neurological disorders. The book introduces the reader to sources of aluminium exposure, followed by an explanation of pharmacokinetics of aluminium and the different biochemical pathways that cause neurological effects. Chapters cover the typical mechanisms associated with aluminium neurotoxicity such as synaptic impairment as well as recent topics of interest such as the role of aluminum in impairing blood-brain barrier functions. Separate chapters which cover clinical evidence of aluminium toxicity and its management are also included in the book.

Biochemical Mechanisms of Aluminium Induced Neurological Disorders is a concise, yet informative reference on the subject of aluminium neurotoxicity for all readers, whether they are students of biochemistry, pharmacology and toxicology, clinical neurologists, environmentalists interested in metal pollution or general readers who want to learn about the toxic effects of aluminium in humans.

Audience: Students (biochemistry, toxicology and pharmacology), medical specialists (internal medicine and neurology), environmental scientists and general readers

Contributors

Editor(s):
Touqeer Ahmed
Department of Healthcare Biotechnology
Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Islamabad
Pakistan




Contributor(s):
Abida Zulfiqar
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Amna Liaqat
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Armeen Hameed
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Fatima Javed Mirza
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Ghazal Iqbal
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Laraib Liaquat
Multidisciplinary Research Lab, Bahria University Medical and Dental College
Bahria University
Karachi
Pakistan


Rida Nisar
HEJ Research Institute of Chemistry
International Center for Chemical and Biological Sciences, University of Karachi
Karachi
Pakistan


Saadia Zahid
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Saida Haider
Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry
University of Karachi
Karachi
Pakistan


Sanila Amber
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Sara Ishaq
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Syeda Mehpara Farhat
Department of Biological Sciences
National University of Medical Sciences
Rawalpindi-46000
Pakistan


Touqeer Ahmed
Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Sector H-12, Islamabad 44000
Pakistan


Tuba Sharf Batool
Atta-ur-Rahman School of Applied Biosciences
National University of Sciences and Technology
Islamabad
Pakistan


Zehra Batool
Dr. Panjwani Center for Molecular Medicine and Drug Research
International Center for Chemical and Biological Sciences, University of Karachi
Karachi
Pakistan