Editors: Mohamed A. Imam, Martyn Snow

Bone Marrow Aspirate Concentrate and Expanded Stem Cell Applications in Orthopaedics

eBook: US $69 Special Offer (PDF + Printed Copy): US $153
Printed Copy: US $119
Library License: US $276
ISBN: 978-1-68108-650-7 (Print)
ISBN: 978-1-68108-649-1 (Online)
Year of Publication: 2018
DOI: 10.2174/97816810864911180101

Introduction

This reference presents insights into the development of bone marrow aspirate stem cell (BMAC) technology and the potential role of stem cell expansion in the regeneration of damaged and deficient musculoskeletal tissues. The book features valuable contributions from stem cell therapy experts from around the world. The authors explain the production, proliferation, differentiation into various tissues, and medical applications of stem cells. In addition to work on the use of stem cells in the treatment of non-unions and bone defects, the book explores the potential for articular cartilage regeneration, repair of tendon injuries, the treatment of degenerative joint disease, revascularization of bone and regeneration of damaged nerves as well as spinal cord injury. The authors also explain ethical challenges faced by researchers and public authorities working on stem cells and the varying constraints on the development of this technology around the world.

Scientists and surgeons, alike, who are involved in the fields of orthopaedics, rheumatology, stem cell and regenerative medicine will benefit from the illuminating snapshot of the applications of BMAC stem cell expansion presented in the volume.

Foreword

- Pp. i
Richard E Field
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Preface

- Pp. ii
Mohamed A Imam and Martyn Snow
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Dedication

- Pp. iii
Mohamed Imam and Martyn Snow
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Acknowledgement

- Pp. iv
Mohamed A Imam and Martyn Snow
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List of Contributors

- Pp. v-vi (2)
Mohamed A Imam and Martyn Snow
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Introduction

- Pp. 1-4 (4)
Mohamed A. Imam, Yasser Elsherbini and Martyn Snow

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Basic Sciences Behind BMAC and Expanded Stem Cells

- Pp. 5-21 (17)
Mohamed Ahmed Mandour, Asmaa Kamal Abdel Maogood, Eman Gamal Ahmed and Rania Mohammed Kishk

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Ethics in the Clinical Use and Research of Stem Cells and BMAC

- Pp. 22-35 (14)
Ahmed Negida, Ahmed Elgebaly, Daniel Jackson and Mohamed A. Imam

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How to Design Clinical Trials of Stem Cells and BMAC in Orthopedic Surgery

- Pp. 36-50 (15)
Ahmed S. Negida, Salma Y. Fala, Mohamed A. Imam and Bassem T. Elhassan

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Role in Non-union and Bone Defects

- Pp. 51-59 (9)
Khaled Emara, Ramy Ahmed Diab and Ahmed K. Emara

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Management of Osteoarthritis

- Pp. 60-67 (8)
Mohamed A. Mokhtar, Mohamed A. Imam, Florian Grubhofer and Asser A. Sallam

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Clinical Applications in Cartilage Pathology

- Pp. 68-74 (7)
James Holton, Mohamed A. Imam, Yasser Elsherbini and Martyn Snow

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Role of BMAC in Avascular Necrosis

- Pp. 75-79 (5)
Tomek Kowalski, Mohamed A. Imam, Kuen Chin and Martyn Snow

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Bone Marrow Aspirate Concentrate in Nerve and Spinal Cord Injury

- Pp. 80-89 (10)
Asser A. Sallam, Mohamed A. Imam and Ali Narvani

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Uses in Spine Surgery

- Pp. 90-95 (6)
Asser A. Sallam, Amr Sami Hussien and Oscar Garcia Casas

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Role of BMAC in Tendinitis or Tendon Pathology

- Pp. 96-103 (8)
Saman Horriat, Mohamed A. Imam, Lukas Ernstbrunner and Rohit Gupta

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BMAC in Foot and Ankle Surgery

- Pp. 104-107 (4)
Mohamed A. Imam, Mohamed Shehata, Saqib Javed and Arshad Khaleel

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Risks of Bone Marrow Aspirate Concentrate

- Pp. 108-111 (4)
Benjamin David and Kevin Newman

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Subject Index

- Pp. 112-116 (5)
Mohamed A Imam and Martyn Snow
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