Editors: Mohamed A. Imam, Martyn Snow

Bone Marrow Aspirate Concentrate and Expanded Stem Cell Applications in Orthopaedics

eBook: US $69 Special Offer (PDF + Printed Copy): US $153
Printed Copy: US $119
Library License: US $276
ISBN: 978-1-68108-650-7 (Print)
ISBN: 978-1-68108-649-1 (Online)
Year of Publication: 2018
DOI: 10.2174/97816810864911180101


This reference presents insights into the development of bone marrow aspirate stem cell (BMAC) technology and the potential role of stem cell expansion in the regeneration of damaged and deficient musculoskeletal tissues. The book features valuable contributions from stem cell therapy experts from around the world. The authors explain the production, proliferation, differentiation into various tissues, and medical applications of stem cells. In addition to work on the use of stem cells in the treatment of non-unions and bone defects, the book explores the potential for articular cartilage regeneration, repair of tendon injuries, the treatment of degenerative joint disease, revascularization of bone and regeneration of damaged nerves as well as spinal cord injury. The authors also explain ethical challenges faced by researchers and public authorities working on stem cells and the varying constraints on the development of this technology around the world.

Scientists and surgeons, alike, who are involved in the fields of orthopaedics, rheumatology, stem cell and regenerative medicine will benefit from the illuminating snapshot of the applications of BMAC stem cell expansion presented in the volume.


- Pp. i
Richard E Field
Download Free


- Pp. ii
Mohamed A Imam, Martyn Snow
Download Free


- Pp. iii
Mohamed Imam, Martyn Snow
Download Free


- Pp. iv
Mohamed A Imam, Martyn Snow
Download Free

List of Contributors

- Pp. v-vi (2)
Mohamed A Imam, Martyn Snow
Download Free


- Pp. 1-4 (4)
Mohamed A. Imam, Yasser Elsherbini, Martyn Snow
View Abstract

Basic Sciences Behind BMAC and Expanded Stem Cells

- Pp. 5-21 (17)
Mohamed Ahmed Mandour, Asmaa Kamal Abdel Maogood, Eman Gamal Ahmed, Rania Mohammed Kishk
View Abstract

Ethics in the Clinical Use and Research of Stem Cells and BMAC

- Pp. 22-35 (14)
Ahmed Negida, Ahmed Elgebaly, Daniel Jackson, Mohamed A. Imam
View Abstract

How to Design Clinical Trials of Stem Cells and BMAC in Orthopedic Surgery

- Pp. 36-50 (15)
Ahmed S. Negida, Salma Y. Fala, Mohamed A. Imam, Bassem T. Elhassan
View Abstract

Role in Non-union and Bone Defects

- Pp. 51-59 (9)
Khaled Emara, Ramy Ahmed Diab, Ahmed K. Emara
View Abstract

Management of Osteoarthritis

- Pp. 60-67 (8)
Mohamed A. Mokhtar, Mohamed A. Imam, Florian Grubhofer, Asser A. Sallam
View Abstract

Clinical Applications in Cartilage Pathology

- Pp. 68-74 (7)
James Holton, Mohamed A. Imam, Yasser Elsherbini, Martyn Snow
View Abstract

Role of BMAC in Avascular Necrosis

- Pp. 75-79 (5)
Tomek Kowalski, Mohamed A. Imam, Kuen Chin, Martyn Snow
View Abstract

Bone Marrow Aspirate Concentrate in Nerve and Spinal Cord Injury

- Pp. 80-89 (10)
Asser A. Sallam, Mohamed A. Imam, Ali Narvani
View Abstract

Uses in Spine Surgery

- Pp. 90-95 (6)
Asser A. Sallam, Amr Sami Hussien, Oscar Garcia Casas
View Abstract

Role of BMAC in Tendinitis or Tendon Pathology

- Pp. 96-103 (8)
Saman Horriat, Mohamed A. Imam, Lukas Ernstbrunner, Rohit Gupta
View Abstract

BMAC in Foot and Ankle Surgery

- Pp. 104-107 (4)
Mohamed A. Imam, Mohamed Shehata, Saqib Javed, Arshad Khaleel
View Abstract

Risks of Bone Marrow Aspirate Concentrate

- Pp. 108-111 (4)
Benjamin David, Kevin Newman
View Abstract

Subject Index

- Pp. 112-116 (5)
Mohamed A Imam, Martyn Snow
Download Free


.Stem Cells in Clinical Application and Productization.
.Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications.
.The Regeneration Promise: The Facts behind Stem Cell Therapies.
.Vascularization in Tissue Engineering.