Editor: Vikas Anand Saharan

Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms

eBook: US $129 Special Offer (PDF + Printed Copy): US $236
Printed Copy: US $171
Library License: US $516
ISBN: 978-1-68108-460-2 (Print)
ISBN: 978-1-68108-459-6 (Online)
Year of Publication: 2017
DOI: 10.2174/97816810845961170101

Introduction

Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have been commercially available since the late 1990s. FDDFs were initially available as orodispersible tablets, and later, as orodipsersible films for treating specific populations (pediatrics, geriatrics, and psychiatric patients). Granules, pellets and mini tablets are among latest additions to these dosage forms, which are still in the development pipeline. As drug delivery systems, FDDFs enable quicker onset of action, immediate drug delivery, and sometimes offer bioavailability benefits due to buccal/sublingual absorption. With time, FDDF have evolved to deliver drugs in a sustained and controlled manner. Their current market and application is increasing in demands with advances in age adapted dosage forms for different patients and changing regulatory requirements that warrant mandatory assessments of new drugs and drug products before commercial availability.

This book presents detailed information about FDDFs from their inception to recent developments. Readers will learn about the technical details of various FDDF manufacturing methods, formulation aspects, evaluation and methods to conduct clinical studies. The authors also give examples of marketed fast disintegrating/dissolving drug products in US, Europe, Japan, and India. This reference is ideal for pharmacology students at all levels seeking information about this specific form of drug delivery and formulation.

Contributors

Editor(s):
Vikas Anand Saharan




Contributor(s):
Anupama Singh
Department of Pharmacognosy, School of Pharmaceutical Sciences
Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences & Research (SBSPGI), Balawala, Dehradun 248161
India


Arpita Jindal
Department of Clinical Pharmacy, Division of Pharmaceutical Sciences
Shri Guru Ram Rai Institute of Technology and Science, Dehradun 248001, Uttarakhand
India


D. N. Mishra
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana
India


Hemant Jadhav
Department of Pharmacy
Birla Institute of Technology and Science, Pilani Campus, Vidya Vihar, Pilani 333031, Jhunjhunu, Rajasthan
India


Kalpana Nagpal
Amity Institute of Pharmacy, Amity University, Noida, Uttar Pradesh 201303
India


Mahaveer Singh
Department of Pharmacy
Birla Institute of Technology and Science, Pilani Campus, Vidya Vihar, Pilani 333031, Jhunjhunu, Rajasthan
India


Prashant Mathur
Department of Clinical Pharmacy, Division of Pharmaceutical Sciences
Shri Guru Ram Rai Institute of Technology and Science, Dehradun 248001, Uttarakhand
India


Shailendra K. Singh
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana
India


Sokindra Kumar
RV Northland Institute of Pharmacy
Greater Noida 203207, Uttar Pradesh
India


Vandana Kharb
Sachdeva College of Pharmacy, Chandigarh-Ludhiana National Highway, Gharuan 140413, Punjab
India


Vikas A. Saharan
Department of Pharmaceutics, School of Pharmaceutical Sciences
Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences & Research (SBSPGI), Balawala, Dehradun 248161
India




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