Editors: Monica Neagu, Cristiana Tanase

Stem Cells between Regeneration and Tumorigenesis

eBook: US $39 Special Offer (PDF + Printed Copy): US $174
Printed Copy: US $155
Library License: US $156
ISBN: 978-1-68108-332-2 (Print)
ISBN: 978-1-68108-331-5 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810833151160101

Introduction

Experts in the field of cellular biology have shown that the reactivation of pluripotency inherent in all cells can allow us to reprogram cells into a specific cell line. This reprogramming paradigm is steadily enhancing our understanding of cell differentiation processes and cellular identity. Consequently, new prospects for cellular therapies of diseases and in vivo regeneration have risen.

Stem Cells Between Regeneration and Tumorigenesis focuses on organ specific molecular pathways that trigger two opposite ways that a stem cell can grow (regeneration and neoplasia). Chapters provide a balanced set of information about tissue regeneration and tumorigenesis in several tissues and biological systems (the nervous, circulatory, oral, skin, digestive and endocrine systems). Additional reviews of the immunological role in regulating the two stem cell growth processes and the role of genomics and proteomics in understanding these processes round up the contents of this monograph.

Readers of this book will gain the following key benefits:

-an insight into the complexity and controversy surrounding the established dual stem cell behavior paradigm (regeneration versus tumorigenesis)

-an understanding of the intricate cellular processes such as stem cells maintenance

-background knowledge of optimizing tailored therapy in personalized and regenerative medicine

Stem Cells Between Regeneration and Tumorigenesis is a useful resource for advanced graduates and researchers undertaking courses in molecular biology and personalized medicine, as well as interns involved in stem cell research programs.

Contributors

Editor(s):
Monica Neagu


Cristiana Tanase




Contributor(s):
Adrian Claudiu Popa
Department of Cellular and Molecular Medicine
Carol Davila University of Medicine and Pharmacy
Bucharest
Romania
/
Army Centre for Medical Research
Bucharest
Romania


Alin Cheran
Ross University School of Medicine
New Jersey
USA


Ana Caruntu
“Dan Theodorescu” Oral and Maxillofacial Surgery Hospital
Bucharest
Romania


Ana-Maria Enciu
Department of Cellular and Molecular Medicine
Carol Davila University of Medicine and Pharmacy
Bucharest
Romania
/
V.Babes National Institute of Pathology
Bucharest
Romania


Ancuta Augustina Gheorghisan-Galateanu
Department of Cellular and Molecular Biology and Histology
“Carol Davila” University of Medicine and Pharmacy
Bucharest
Romania
/
“C.I.Parhon” National Institute of Endocrinology
Bucharest
Romania


Andreea-Roxana Lupu
Immunobiology Laboratory
“Victor Babeş” National Institute of Pathology
Bucharest
Romania


Carolina Constantin
Immunobiology Laboratory
“Victor Babeş” National Institute of Pathology
Bucharest
Romania


Caterina Longo
Dermatology and Skin Cancer Unit
Arcispedale S Maria Nuova
Reggio Emilia
Italy


Constantin Caruntu
Immunology Department
“Victor Babes” National Institute of Pathology
Bucharest
Romania
/
Department of Physiology
“Carol Davila” University of Medicine and Pharmacy
Bucharest
Romania


Cristiana Pistol Tanase
“Victor Babes” National Institute of Pathology
Biochemistry-Proteomics Department
Bucharest
Romania
/
Faculty of Medicine
“Titu Maiorescu” University
Bucharest
Romania


Dana Cucu
“Dan Setlacec” Center of General Surgery and Liver Transplantation
Fundeni Clinical Institute
Bucharest
Romania
/
The Department of Anatomy, Physiology and Biophysics, Faculty of Biology
University of Bucharest
Bucharest
Romania


Daniel Boda
Dermatology Research Laboratory
“Carol Davila” University of Medicine and Pharmacy
Bucharest
Romania


Elena Codrici
“Victor Babes” National Institute of Pathology
Biochemistry-Proteomics Department
Bucharest
Romania


Ionela Daniela Popescu
“Victor Babes” National Institute of Pathology
Biochemistry-Proteomics Department
Bucharest
Romania


Irinel Popescu
“Dan Setlacec” Center of General Surgery and Liver Transplantation
Fundeni Clinical Institute
Bucharest
Romania


Larisa-Emilia Cheran
Department of Chemistry
University of Toronto
Toronto
Ontario
Canada


Laura Necula
“Victor Babes” National Institute of Pathology
Biochemistry-Proteomics Department
Bucharest
Romania
/
“Stefan S. Nicolau”
Institute of Virology, Cellular and Molecular Pathology
Bucharest
Romania


Maria Linda Cruceru
Department of Cellular and Molecular Medicine
Carol Davila University of Medicine and Pharmacy
Bucharest
Romania


Monica Neagu
Immunobiology Laboratory
“Victor Babeş” National Institute of Pathology
Bucharest
Romania
/
Faculty of Biology
University of Bucharest
Bucharest
Romania


Nicolae Bacalbasa
“Carol Davila” University of Medicine and Pharmacy
Bucharest
Romania


Pieter J Slootweg
Department of Pathology
Radboud University Medical Centre Nijmegen
Netherlands


Qiang Huang
School of Pharmaceutical Sciences
Sun Yat-Sen University
Guangzhou
China
/
Centre for Cellular & Structural biology
Sun Yat-Sen University
Guangzhou
China


Qing Li
School of Pharmaceutical Sciences
Sun Yat-Sen University
Guangzhou
China
/
Centre for Cellular & Structural biology
Sun Yat-Sen University
Guangzhou
China


Radu Albulescu
“Victor Babes” National Institute of Pathology
Biochemistry-Proteomics Department
Bucharest
Romania
/
Faculty of Medicine
“Titu Maiorescu” University
Bucharest
Romania
/
National Institute for Chemical Pharmaceutical R&D
Bucharest
Romania


Sabina Zurac
Department of Pathology
University of Medicine and Pharmacy Carol Davila, Colentina University Hospital
Bucharest
Romania


Simona Mihai
“Victor Babes” National Institute of Pathology
Biochemistry-Proteomics Department
Bucharest
Romania


Simona Olimpia Dima
“Dan Setlacec” Center of General Surgery and Liver Transplantation
Fundeni Clinical Institute
Bucharest
Romania


Siqi Chen
School of Pharmaceutical Sciences
Sun Yat-Sen University
Guangzhou
China
/
Centre for Cellular & Structural biology
Sun Yat-Sen University
Guangzhou
China


Traian Popescu
National Institute of Materials Physics
Magurele
Romania


Valeria Tica
“Dan Setlacec” Center of General Surgery and Liver Transplantation
Fundeni Clinical Institute
Bucharest
Romania


Yawei Liu
Health Division of Guard Bureau
General Staff Department of PLA
Beijing
China


Zhong Wang
School of Pharmaceutical Sciences
Sun Yat-Sen University
Guangzhou
China
/
Centre for Cellular & Structural biology
Sun Yat-Sen University
Guangzhou
China




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