Editors: Robert F. Diegelmann, Charles E. Chalfant

Series Title: Frontiers in Inflammation

Basic Biology and Clinical Aspects of Inflammation

Volume 1

eBook: US $129 Special Offer (PDF + Printed Copy): US $226
Printed Copy: US $162
Library License: US $516
ISSN: 2468-1466 (Print)
ISSN: 2468-1474 (Online)
ISBN: 978-1-68108-228-8 (Print)
ISBN: 978-1-68108-227-1 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810822711160101


Basic Biology and Clinical Aspects of Inflammation provides information about the critical cells and biochemical mediators involved in the complex process of inflammation. Readers are introduced to the basic scientific background on the subject, after which the book progresses towards translational research in clinical settings. Topics covered in this volume include, the modulation of inflammation during normal and chronic wound healing, altered metabolism during inflammation processes, the effect of ageing on inflammatory processes, as well as details about the underlying molecular processes behind specific clinical pathologies that are driven by excessive inflammation in the body (allergic reactions, type 2 diabetes, cardiac and vascular disease, arthritis, periodontal disease, inflammatory bowel disease and neuroinflammation). The volume also provides the latest information on pharmacotherapy for inflammation and interesting contributions towards the mathematical modeling and network analysis of inflammation. Basic Biology and Clinical Aspects of Inflammation features contributions from by a distinguished group of international researchers and clinicians highly recognized for their specific expertise in the field of inflammation. The information presented in this reference is useful to academics, medical professionals, health care regulators and pharmaceutical scientists.


- Pp. i-ii (2)
Charles N. Serhan
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- Pp. iii
Robert F. Diegelmann, Charles E. Chalfant
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List of Contributors

- Pp. iv-vi (3)
Robert F. Diegelmann, Charles E. Chalfant
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Introduction to Basic Biology and Clinical Aspects of Inflammation

- Pp. 3-10 (8)
Roger M. Loria, Robert F. Diegelmann
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Cell Mediators of Acute Inflammation

- Pp. 11-25 (15)
Luisa A. DiPietro, Megan E. Schrementi
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Biochemical Mediators of Inflammation and Resolution

- Pp. 26-54 (29)
Jennifer A. Mietla, L. Alexis Hoeferlin, Dayanjan S. Wijesinghe, Charles E. Chalfant
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Wound Healing and Dermatologic Aspects of Inflammation

- Pp. 55-82 (28)
Lisa J. Gould, Mary Elizabeth Hanley
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Metabolic Regulation of Inflammation

- Pp. 83-105 (23)
Chang-An Guo, Laura Bond, James M. Ntambi
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Aging and Inflammation

- Pp. 106-137 (32)
Daipayan Banerjee, Alexander A. Karakashian, Mariana N. Nikolova- Karakashian
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Allergic Inflammation

- Pp. 138-163 (26)
Joshua L. Kennedy, Matthew C. Bell
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Inflammation in Type 2 Diabetes

- Pp. 164-179 (16)
Agbor Ndip, Edward B. Jude, Andrew J.M. Boulton
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The Vascular Tree and Heart with Relationship to Inflammation

- Pp. 180-219 (40)
Bruce D. Spiess
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Rheumatoid and Degenerative Arthritis-Associated Inflammation

- Pp. 220-253 (34)
Matthias Geyer, Steffen Gay, Ulf Müller-Ladner
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Inflammation in Oral Diseases

- Pp. 254-291 (38)
Praveen R. Arany
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Intestinal Inflammation and Inflammatory Bowel Disease

- Pp. 292-304 (13)
Chao Li, John F. Kuemmerle
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- Pp. 305-376 (72)
Unsong Oh
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Pharmacotherapy for Inflammatory Processes

- Pp. 377-426 (50)
Graham A. Mackay, Alastair G. Stewart
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Mathematical Modeling of Inflammation

- Pp. 427-450 (24)
Angela M. Reynolds, Rebecca A. Segal
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Network Analysis of Inflammation

- Pp. 451-473 (23)
Tomasz Arodz, Xi Gao
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Subject Index

- Pp. 474-477 (4)
Robert F. Diegelmann, Charles E. Chalfant
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.The NLRP3 Inflammasome: An Attentive Arbiter of Inflammatory Response.
.Natural Immunomodulators: Promising Therapy for Disease Management.
.Herbal Immunity Boosters Against COVID-19.
.Mitochondrial DNA and the Immuno-inflammatory Response: New Frontiers to Control Specific Microbial Diseases.