Editors: Robert F. Diegelmann, Charles E. Chalfant

Series Title: Frontiers in Inflammation

Basic Biology and Clinical Aspects of Inflammation

Volume 1

eBook: US $129 Special Offer (PDF + Printed Copy): US $226
Printed Copy: US $162
Library License: US $516
ISSN: 2468-1466 (Print)
ISSN: 2468-1474 (Online)
ISBN: 978-1-68108-228-8 (Print)
ISBN: 978-1-68108-227-1 (Online)
Year of Publication: 2016
DOI: 10.2174/97816810822711160101


Basic Biology and Clinical Aspects of Inflammation provides information about the critical cells and biochemical mediators involved in the complex process of inflammation. Readers are introduced to the basic scientific background on the subject, after which the book progresses towards translational research in clinical settings. Topics covered in this volume include, the modulation of inflammation during normal and chronic wound healing, altered metabolism during inflammation processes, the effect of ageing on inflammatory processes, as well as details about the underlying molecular processes behind specific clinical pathologies that are driven by excessive inflammation in the body (allergic reactions, type 2 diabetes, cardiac and vascular disease, arthritis, periodontal disease, inflammatory bowel disease and neuroinflammation). The volume also provides the latest information on pharmacotherapy for inflammation and interesting contributions towards the mathematical modeling and network analysis of inflammation. Basic Biology and Clinical Aspects of Inflammation features contributions from by a distinguished group of international researchers and clinicians highly recognized for their specific expertise in the field of inflammation. The information presented in this reference is useful to academics, medical professionals, health care regulators and pharmaceutical scientists.


In recent years there have been many exciting advances made in the field of inflammation. State of the art scientific technologies have helped make these advances possible. As underlying cellular and biochemical mechanisms responsible for the inflammatory response are better understood, new therapeutic strategies can be developed to treat the spectrum of clinical problems associated with excessive inflammation.

This educational eBook, “Basic Biology and Clinical Aspects of Inflammation” was developed for a wide audience. Basic scientists, academicians, clinicians, health care regulators, industrial and pharmaceutical scientists as well as the lay public can benefit from the expanse of knowledge presented herein.

To help continue promoting cutting edge scientific research and technology, the Editors and all contributing Authors have agreed to donate their royalties from this eBook to the Wound Healing Foundation (http://www.woundhealingfoundation.org) for young investigator research grants. In addition, we recognize and appreciate Bentham Science Publishers for their generous support and contributions to the Wound Healing Foundation.


We dedicate this book to our wonderful wives, Penny and Laura and our loving children, Sarah, Laura, Ryan, Stephen, Scott, Isabella, and Alec.

Robert F. Diegelmann & Charles Chalfant
Department of Biochemistry and Molecular Biology
Virginia Commonwealth University Medical Center
1101 East Marshall Street
Sanger Hall, room 2-007
Richmond Virginia, 23298-0614


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