Editors: Unax Lertxundi, Juan Medrano, Rafael Hernández

Psychopharmacological Issues in Geriatrics

eBook: US $59 Special Offer (PDF + Printed Copy): US $119
Printed Copy: US $148
Library License: US $236
ISBN: 978-1-68108-035-2 (Print)
ISBN: 978-1-68108-034-5 (Online)
Year of Publication: 2015
DOI: 10.2174/97816810803451150101

Introduction

Demographic changes due to improved life expectancy and access to medical care has increased the number of people aged 65 years and beyond. This raises an important new challenge for healthcare professionals. Changes in organ functions, homeostatic mechanisms and receptor responsiveness impair drug distribution, metabolism and excretion, and reduce the effectiveness of medicines among geriatric patients. As a consequence, management of medical regimens is much more challenging in the elderly than in younger adult patients. Elderly patients are also more susceptible than other age groups to certain drug-drug interactions, drug-disease interactions and adverse drug reactions owing to the number of drugs administered.

Polypharmacy and potentially inappropriate medication is a common finding in the elderly healthcare and it is considered a public health issue related to morbidity, mortality and health care resource use.

Psychopharmacological Issues in Geriatrics can be regarded as a ‘pharmacovigilance’ manual for elderly patients as it presents recommendations for geriatric prescription with specific considerations.

The book also provides a comprehensive review of specific classes of psychopharmacological agents used to treat geriatric patients, including antipsychotics, anxiolytics, hypnotics and mood stabilizers. The book is intended as a handbook for general medical and nursing practitioners.

Foreword

- Pp. i-ii (2)
Enrique Echevarria
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Preface

- Pp. iii-v (3)
Unax Lertxundi, Juan Medrano, Rafael Hernández
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List of Contributors

- Pp. vii
Unax Lertxundi, Juan Medrano, Rafael Hernández
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Historical Perspective of Psychotropic Drug Use

- Pp. 3-15 (13)
Juan Medrano
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Evolution of Psychotropic Drug Use in Elderly Patients: Pharmaceuticals Emerging as Environmental Contaminants

- Pp. 17-30 (14)
Unax Lertxundi, Beatriz Corcostegui
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Age-Related Pharmacokinetic/Pharmacodynamic Changes in Psychopharmacological Drugs

- Pp. 31-48 (18)
Arantxa Isla Ruiz, María Ángeles Solinís Aspiazu, Alicia Rodríguez- Gascón
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Clinically Relevant Psychopharmacological Interactions in the Elderly

- Pp. 49-64 (16)
Ainhoa Urrutia, Javier Peral, Jesús Ángel Padierna
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Potentially Inappropriate Medication in Elderly

- Pp. 65-109 (45)
Rafael Hernández, Ane Gómez de Segura, Juan Medrano, Beatriz Corcóstegui, Unax Lertxundi
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Pharmacovigilance in Geropsychiatry

- Pp. 111-132 (22)
Carmelo Aguirre, Montserrat García
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Anxiolytics and Hypnotics

- Pp. 133-153 (21)
Juan Medrano
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Mood Stabilizers

- Pp. 155-185 (31)
Juan Medrano
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Antidepressants

- Pp. 187-216 (30)
Juan Medrano
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Antipsychotics

- Pp. 217-240 (24)
Juan Medrano
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Antipsychotics in Dementia

- Pp. 241-271 (31)
Juan Medrano
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Antipsychotic Use in Parkinson`s Disease

- Pp. 273-286 (14)
Saioa Domingo-Echaburu
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Antipsychotic Polypharmacy in Elderly Patients

- Pp. 287-304 (18)
Amaia Lopez de Torre
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Drugs Used in Substance Use Disorders

- Pp. 305-324 (20)
Juan Medrano
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Drugs Used in the Treatment of Dementia and Neurocognitive Disorders

- Pp. 325-332 (8)
Juan Medrano
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Subject Index

- Pp. 333-336 (4)
Unax Lertxundi, Juan Medrano, Rafael Hernández
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