Editor: Glaucia Noeli Maroso Hajj

Young Perspectives for Old Diseases

Special Offer (PDF + Printed Copy): US $123
Printed Copy: US $123
ISBN: 978-1-68108-003-1 (Print)
ISBN: 978-1-60805-992-8 (Online)
Year of Publication: 2015
DOI: 10.2174/97816080599281150101


In this book, a great team of young neuroscientists describes the current understanding of common and rare neurodegenerative diseases, focusing on the molecular and cellular aspects of neurodegeneration and the scientific advances for possible therapeutic approaches. These experts in each area reviewed the newest scientific information available, presenting an up-to-date view of the current knowledge and offering reliable information based upon validated research. A prime reading to clinicians, students of the medical and biological areas and other people interested in neurodegenerative diseases.


- Pp. i
Rafael Linden
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- Pp. iii
Glaucia Noeli Maroso Hajj, Carolina Rezával
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List of Contributors

- Pp. v-ix (5)
Glaucia Noeli Maroso Hajj, Carolina Rezával
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The Role of Molecular and Cellular Biology in Neurodegenerative Diseases - Learning from Cancer Therapies

- Pp. 3-21 (19)
Kil Sun Lee
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Current Pharmacological and Non-Pharmacological Therapies for Neurodegenerative Diseases

- Pp. 23-48 (26)
Walter A. S. Moraes
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“The Greatness of the Smallest Ones”: The Most Valuable Attributes of Flies and Worms for the Study of Neurodegeneration

- Pp. 49-84 (36)
Carolina Rezával
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Calcium in Homeostasis and Neurodegeneration

- Pp. 85-101 (17)
Flavio H. Beraldo, Ashbell Roy
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Protein Misfolding and Propagation in Neurodegenerative Diseases

- Pp. 103-118 (16)
Tiago Góss dos Santos
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Mitochondrial Dysfunction and Free Radicals in Neuronal Death

- Pp. 119-132 (14)
Célia Harumi Tengan, Gabriela Silva Rodrigues
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Alzheimer’s Disease

- Pp. 133-154 (22)
Sofia Jurgensen, Helena Decker
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Parkinson’s Disease: Genetics, Mechanisms and Diagnosis

- Pp. 155-176 (22)
Telma Tiemi Schwindt, Enéas Galdini Ferrazoli, Henning Ulrich
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Huntington’s Disease: A Puzzle from Childhood to Senescence

- Pp. 177-203 (27)
Fabiola M. Ribeiro, Roenick P. Olmo, Tomas Dobransky
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Amyotrophic Lateral Sclerosis: A Role for Non-Neuronal Cells

- Pp. 205-222 (18)
Ana G. Barbeito
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Multiple Sclerosis: An Overview

- Pp. 223-250 (28)
Felipe von Glehn, Carlos Otávio Brandão, Alessandro S. Farias, Leonilda M. B. Santos
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Lewy Body Dementia and Frontotemporal Dementia

- Pp. 251-267 (17)
Renan Pedra Souza, Bruno Rezende Souza
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Charcot-Marie-Tooth Disease and Other Peripheral Neuropathies

- Pp. 269-325 (57)
Veronick Benoy, Constantin d`Ydewalle, Ludo Van Den Bosch
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Targeting Molecular Mechanisms of Cognitive Dysfunction

- Pp. 327-340 (14)
Rafael Roesler, Arethuza S. Dornelles, Fernando Benetti
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Stem Cell Applications for Neurodegenerative Diseases

- Pp. 341-362 (22)
Marilene Hohmuth Lopes, Lilian Cruz
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Subject Index

- Pp. 363-370 (8)
Glaucia Noeli Maroso Hajj, Carolina Rezával
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.Frontiers in Clinical Drug Research - CNS and Neurological Disorders.
.Neurodegenerative Diseases: Multifactorial Degenerative Processes, Biomarkers and Therapeutic Approaches.
.Frontiers in Clinical Drug Research - CNS and Neurological Disorders.
.Animal Models for Neurological Disorders.
.Traditional Medicine for Neuronal Health.
.Recent Advances in the Treatment of Neurodegenerative Disorders.
.Advances in Alzheimer Research.