Editor: Atta-ur-Rahman

Frontiers in Clinical Drug Research - HIV

Volume 1

eBook: US $100 Special Offer (PDF + Printed Copy): US $205
Printed Copy: US $155
Library License: US $400
ISSN: 2468-0397 (Print)
ISSN: 2352-5916 (Online)
ISBN: 978-1-60805-897-6 (Print)
ISBN: 978-1-60805-896-9 (Online)
Year of Publication: 2015
DOI: 10.2174/97816080589691140101

Introduction

Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research.

The first volume of this series features 7 chapters that cover a variety of topics including:

  • - Antiretroviral drug development
  • - HIV-1 genomics
  • - HIV drug targets such as ribosomes and HIV Integrase
  • - HAART associated nephrotoxicity

Preface

- Pp. i-ii (2)
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List of Contributors

- Pp. iii-iv (2)
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Antiretroviral Drugs: Current Therapy, Recent Developments and Future Perspectives

- Pp. 3-57 (55)
Matthew Phillips, Jenny Svärd

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New Developments for Anti-HIV Treatment

- Pp. 58-66 (9)
Liã Bárbara Arruda, Jorge Casseb

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Drugs Targeting the -1 Ribosomal Frameshifting that Generates the Enzymes of the Human Immunodeficiency Virus

- Pp. 67-82 (16)
Léa Brakier-Gingras, Johanie Charbonneau, Benjamin L. Miller
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Sensing of SNP in HIV-1 Genome Using Fluorescent Oligonucleotide Probes

- Pp. 83-122 (40)
Kira Astakhova

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Next Generation Anti-HIV Agent 4’-Ethynylstavudine: From the Bench to the Clinic

- Pp. 123-184 (62)
Kazuhiro Haraguchi, Shingo Takeda, Yutaka Kubota, Hiroki Kumamoto, Hiromichi Tanaka, Takayuki Hamasaki, Masanori Baba, Elijah Paintsil, Yung-Chi Cheng, Yasuo Urata

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HIV Integrase - Biology and Inhibitor Design

- Pp. 185-265 (81)
Victoria Hann, Mark Ashton

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Nephrotoxicity Associated with HAART

- Pp. 266-286 (21)
Siddhartha Yedla, Parikshit T. Hameer, Naheed Ansari

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Subject Index

- Pp. 287-292 (6)
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