Editor: Atta-ur-Rahman

Frontiers in Clinical Drug Research - HIV

Volume 1

eBook: US $100 Special Offer (PDF + Printed Copy): US $191
Printed Copy: US $141
Library License: US $400
ISSN: 2468-0397 (Print)
ISSN: 2352-5916 (Online)
ISBN: 978-1-60805-897-6 (Print)
ISBN: 978-1-60805-896-9 (Online)
Year of Publication: 2015
DOI: 10.2174/97816080589691140101


Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research.

The first volume of this series features 7 chapters that cover a variety of topics including:

  • - Antiretroviral drug development
  • - HIV-1 genomics
  • - HIV drug targets such as ribosomes and HIV Integrase
  • - HAART associated nephrotoxicity


- Pp. i-ii (2)
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List of Contributors

- Pp. iii-iv (2)
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Antiretroviral Drugs: Current Therapy, Recent Developments and Future Perspectives

- Pp. 3-57 (55)
Matthew Phillips and Jenny Svärd

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New Developments for Anti-HIV Treatment

- Pp. 58-66 (9)
Liã Bárbara Arruda and Jorge Casseb

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Drugs Targeting the -1 Ribosomal Frameshifting that Generates the Enzymes of the Human Immunodeficiency Virus

- Pp. 67-82 (16)
Léa Brakier-Gingras, Johanie Charbonneau and Benjamin L. Miller
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Sensing of SNP in HIV-1 Genome Using Fluorescent Oligonucleotide Probes

- Pp. 83-122 (40)
Kira Astakhova

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Next Generation Anti-HIV Agent 4’-Ethynylstavudine: From the Bench to the Clinic

- Pp. 123-184 (62)
Kazuhiro Haraguchi, Shingo Takeda, Yutaka Kubota, Hiroki Kumamoto, Hiromichi Tanaka, Takayuki Hamasaki, Masanori Baba, Elijah Paintsil, Yung-Chi Cheng and Yasuo Urata

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HIV Integrase - Biology and Inhibitor Design

- Pp. 185-265 (81)
Victoria Hann and Mark Ashton

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Nephrotoxicity Associated with HAART

- Pp. 266-286 (21)
Siddhartha Yedla, Parikshit T. Hameer and Naheed Ansari

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Subject Index

- Pp. 287-292 (6)
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