Editors: Marcel Popa , Constantin V. Uglea

Polymeric Nanomedicines

Personal Book: US $169 Special Offer (PDF + Printed Copy): US $287
Printed Copy: US $203
Library Book: US $676
ISBN: 978-1-60805-628-6
eISBN: 978-1-60805-484-8 (Online)
Year of Publication: 2013
DOI: 10.2174/97816080548481130101

Introduction

Over the last few decades, numerous nanoparticle platforms have been studied for their use in therapeutic applications. This book deals with the description of the construction of technical systems that combines different functionalities which bring liposomes, polymer-drug conjugates, polymer-protein conjugates, dendrimers, polymeric micelles, polymerosomes and other nanoparticles into the realm of nanotechnology proper, as opposed to traditional pharmacology or supramolecular chemistry. The volume additionally covers topics such as passive and active targeting, the strategies used for drug targeting, and the synthesis and characterization of polymeric nanoparticle platforms. Targeted polymeric nanomedicines have shown exciting results in preclinical studies, demonstrating their potential as therapeutic carriers. Therefore, the development of polymeric nanomedicines as therapeutic agents has generated great enthusiasm both in academia and industry.

The book is systematically divided into chapters devoted to a class of polymeric nanomedicines. Each chapter also describes relevant aspects relating to drug design and targeting of polymeric nanomedicines wherever possible.

In addition, a series of chapters concerning the contribution of polymeric nanomedicines in the treatment of several categories of diseases including cancer, inflammatory, renal, immunological diseases, and brain disorders is also presented.

Key features of this book include:

- A comprehensive and cutting-edge overview of polymeric nanomedicines available in a single dedicated volume

- Discussions on advances in drug delivery systems for a variety of diseases

- more than 2000 references, tables, equations, and drawings

Readers, whether beginners or experts, will find in this book, contemporary and relevant information regarding the synthesis, evaluation and applications of polymeric nanomedicines. Supplemented with extensive bibliographic references, tables and figures, this book is an essential and incomparable reference for medicinal chemists, biologists, and medical (oncologic) researchers, as well as for scientists, undergraduate and graduate students in the field of medical bioengineering and polymer nanoscience.

Contributors

Editor(s):
Marcel Popa
"Gheorghe Asachi" Technical University of Iasi
Romania


Constantin V. Uglea
"Grigore T. Popa" University of Medicine and Pharmacy Iasi
Romania




Contributor(s):
Daniela Ailincăi
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Natural and Synthetic Polymers
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Paul Botez
“Grigore T. Popa” University of Medicine and Pharmacy Iasi
Department of Medical Bioengineering
Universitatii Str., no. 16
700115 Iasi
Romania


Dănuţ Costin
“Grigore T. Popa” University of Medicine and Pharmacy Iasi
Department of Medical Bioengineering
Universitatii Str., no. 16
700115 Iasi
Romania


Lucian Eva
“Prof. Dr. Nicolae Oblu” Clinical Emergency Hospital
Neurosurgery Section
Ateneului Str., no. 2
700309 Iasi
Romania


Mihaela Holban
“Al.I.Cuza” University, Faculty of Chemistry
Department of Organic Chemistry
Carol I Blv., no. 11
700506, Iasi
Romania


Leonard Ignat
“Petru Poni” Institute of Macromolecular Chemistry
Gr. Ghica Voda Alley, no. 41A
700487 Iasi
Romania


Delia Iurea (Raţă)
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Natural and Synthetic Polymers
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Anca N. Cadinoiu
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Natural and Synthetic Polymers
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Maria-Andreea Lungan
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Natural and Synthetic Polymers
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Gabriela Lupescu (Andrei)
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Natural and Synthetic Polymers
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Raluca Munteanu
“Prof. Dr. Nicolae Oblu” Clinical Emergency Hospital
Neurosurgery Section
Ateneului Str., no. 2
700309 Iasi
Romania


Ioan I. Negulescu
Louisiana State University AgCenter
School of Human Ecology
Baton Rouge
LA , 70803
USA


Ovidiu Novac
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Physical Chemistry
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Lacramioara Ochiuz
“Grigore T. Popa” University of Medicine and Pharmacy Iasi
Faculty of Pharmacy
Department of Pharmaceutical Technology
Universitatii Str., no. 16
700115 Iasi
Romania


Cătălina A. Peptu
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Natural and Synthetic Polymers
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Cristian Peptu
“Petru Poni” Institute of Macromolecular Chemistry
Gr. Ghica Voda Alley, no. 41A
700487 Iasi
Romania


Marcel Popa
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Natural and Synthetic Polymers
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Marcel I. Popa
“Gheorghe Asachi” Technical University of Iasi
Faculty of Chemical Engineering and Environmental Protection
Department of Physical Chemistry
Prof. dr. docent Dimitrie Mangeron Str., no. 73
700050 Iasi
Romania


Stefania Racovita
“Petru Poni” Institute of Macromolecular Chemistry
Gr. Ghica Voda Alley, no. 41A
700487 Iasi
Romania


Constantin V. Uglea
“Grigore T. Popa” University of Medicine and Pharmacy Iasi
Department of Medical Bioengineering
Universitatii Str., no. 16
700115 Iasi
Romania


Silvia Vasiliu
“Petru Poni” Institute of Macromolecular Chemistry
Gr. Ghica Voda Alley, no. 41A
700487 Iasi
Romania


Cristina D. Vlad
“Petru Poni” Institute of Macromolecular Chemistry
Gr. Ghica Voda Alley, no. 41A
700487 Iasi
Romania