Frontiers in Medicinal Chemistry

Volume 6

eBook: US $129 Special Offer (PDF + Printed Copy): US $243
Printed Copy: US $179
Library License: US $516
ISSN: 1567-2042 (Print)
ISSN: 1875-5763 (Online)
ISBN: 978-1-60805-561-6 (Print)
ISBN: 978-1-60805-464-0 (Online)
Year of Publication: 2012
DOI: 10.2174/97816080546401130601

Introduction

“Frontiers in Medicinal Chemistry” is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. “Frontiers in Medicinal Chemistry” covers all the areas of medicinal chemistry, including developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships.

Medicinal chemistry as a discipline is rapidly maturing. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. “Frontiers in Medicinal Chemistry” aims to contribute in a major way to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. This Ebook series is essential for any medicinal chemist who wishes to be kept informed and up-to-date with the latest and the most important advances.

Indexed in: Scopus, Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, EMBASE, Chemical Abstracts, EBSCO, Ulrich's Periodicals Directory.

Contributors

Co-Editor(s):
Atta-ur- Rahman
International Center for Chemical and Biological Sciences (HEJ Research Institute of Chemistry
Dr. Panjwani Center for Molecular, Medicine & Drug Research), University of Karachi
Karachi, 75270
Pakistan


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc
Doylestown
PA , 18902
USA


M. Iqbal Choudhary
International Center for Chemical and Biological Sciences (HEJ Research Institute of Chemistry
Dr. Panjwani Center for Molecular, Medicine & Drug Research), University of Karachi
Karachi, 75270
Pakistan




Contributor(s):
Franco Lori
ViroStatics srl,
Alghero
Italy


Julianna Lisziewicz
kft
Budapest
Hungary


Davide De Forni
ViroStatics srl
Alghero
Italy


Mike Stevens
ViroStatics srl
Princeton
United States


Shin-Ru Shih
Research Center for Emerging Viral Infections, Department of Medical Biotechnology & Laboratory Science
Chang-Gung University
Taiwan


Gary Brewer
Biochemistry and Molecular Biology
UMDNJ-Robert Wood Johnson Medical School
Piscataway
NJ , 08854
USA


Peng-Nien Huang
Research Center for Emerging Viral Infections, Department of Medical Biotechnology & Laboratory Science
Chang-Gung University
Taiwan


Kuo-Feng Weng
Research Center for Emerging Viral Infections, Department of Medical Biotechnology & Laboratory Science
Chang-Gung University
Taiwan


Chin Li
Department of Life Science and Graduate Institute of Molecular Biology
National Chung Cheng University
Chiayi,
Taiwan


Hongtao Wang
Department of Molecular Genetics, Microbiology & Immunology
UMDNJ-Robert Wood Johnson Medical School
Piscataway
NJ, 08854
USA


Tzu-Chun Chen
Department of Microbiology and Immunology
Stanford University
Stanford
CA , 94305
USA


Mei-Ling Li
Biochemistry and Molecular Biology
UMDNJ-Robert Wood Johnson Medical School
Piscataway
NJ , 08854
USA


Eugene D. Weinberg
Department of Biology and Program in Medical Sciences
Indiana University
Bloomington
IN
USA


Roland P. Lange
Actelion Pharmaceuticals Ltd.
Gewerbestrasse 1,
Allschwil, 4123
Switzerland


Hans H. Locher
Actelion Pharmaceuticals Ltd.
Gewerbestrasse 1,
Allschwil, 4123
Switzerland


Pierre C. Wyss
Actelion Pharmaceuticals Ltd.
Gewerbestrasse 1,
Allschwil, 4123
Switzerland


Rudolf L. Then
Actelion Pharmaceuticals Ltd.
Gewerbestrasse 1,
Allschwil, 4123
Switzerland


Jyotsna Mishra
Division of Clinical Microbiology, Department of Laboratory
Medicine, All India Institute of Medical Sciences
New Delhi
India


Anubha Saxena
Division of Clinical Microbiology, Department of Laboratory
Medicine, All India Institute of Medical Sciences
New Delhi
India


Sarman Singh
Division of Clinical Microbiology, Department of Laboratory
Medicine, All India Institute of Medical Sciences
New Delhi
India


Christina Roebke
Department of Otorhinolaryngology, Head, Neck and Plastic Surgery
Lohmuehlenstr. 5
Hamburg, 20099
Germany


Jürgen Harder
Clinical Research Unit, Department of Dermatology
Schittenhelmstr. 11
Kiel, 24105
Germany


Jens E. Meyer
Department of Otorhinolaryngology, Head, Neck and Plastic Surgery
Lohmuehlenstr. 5
Hamburg, 20099
Germany


Guillermo de Cárcer
Cell Division and Cancer Group, Centro Nacional de Investigaciones Oncológicas (CNIO)
Madrid
Spain


Ignacio Pérez de Castro
Cell Division and Cancer Group, Centro Nacional de Investigaciones Oncológicas (CNIO)
Madrid
Spain


Marcos Malumbres
Cell Division and Cancer Group, Centro Nacional de Investigaciones Oncológicas
Madrid
Spain


ORY Benjamin
INSERM, UMR957, Faculté de Médecine, 1 rue Gaston Veil
Université de Nantes, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives
EA3822, 44035 Nantes cedex 1
Nantes, F-44035
France


Moriceau Gatien
INSERM, UMR957, Faculté de Médecine, 1 rue Gaston Veil
Université de Nantes, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives
EA3822, 44035 Nantes cedex 1
Nantes, F-44035
France


Gobin Bérengère
INSERM, UMR957, Faculté de Médecine, 1 rue Gaston Veil
Université de Nantes, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives
EA3822, 44035 Nantes cedex 1
Nantes, F-44035
France


Redini Françoise
INSERM, UMR957, Faculté de Médecine, 1 rue Gaston Veil
Université de Nantes, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives
EA3822, 44035 Nantes cedex 1
Nantes, F-44035
France


Heymann Dominique
INSERM, UMR957, Faculté de Médecine, 1 rue Gaston Veil
Université de Nantes, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives
EA3822, 44035 Nantes cedex 1
Nantes, F-44035
France


Li-Chieh Wang
Department of Pediatrics
National Taiwan University Hospital
Taipei
Taiwan ROC


Jyh-Hong Lee
Department of Pediatrics
National Taiwan University Hospital
Taipei
Taiwan ROC


Yao-Hsu Yang
Department of Pediatrics
National Taiwan University Hospital
Taipei
Taiwan ROC


Yu-Tsan Lin
Department of Pediatrics
National Taiwan University Hospital
Taipei
Taiwan ROC


Bor-Luen Chiang
Department of Pediatrics
National Taiwan University Hospital
Taipei
Taiwan ROC


Elena Matteucci
Department of Internal Medicine
University of Pisa,
Pisa
Italy


Ottavio Giampietro
Department of Internal Medicine
University of Pisa,
Pisa
Italy


Roman G. Efremov
M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry
Russian Academy of Sciences, Ul. Miklukho-Maklaya, 16/10
Moscow V-437
GSP, 117997
Russia


Anton O. Chugunov
M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Department of Bioengineering, Biological Faculty
Russian Academy of Sciences, Ul. Miklukho-Maklaya, 16/10, M.V. Lomonosov Moscow State University, Vorobiovy gory, 119899
Moscow V-437
GSP, 117997
Russia


Timothy V. Pyrkov
M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry
Russian Academy of Sciences, Ul. Miklukho-Maklaya, 16/10
Moscow V-437
GSP, 117997
Russia


John P. Priestle
Novartis Institute for Biomedical Research, WSJ-350.3.15
CH-4002 Basel
Switzerland


Vladimir M. Pentkovsky
Moscow Institute of Physics and Technology (State University)
Institutskii per., 9, Dolgoprudny
Moscow region, 141700
Russia


Alexander S. Arseniev
M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry
Russian Academy of Sciences, Ul. Miklukho-Maklaya, 16/10
Moscow V-437
GSP, 117997
Russia


Edgar Jacoby
Novartis Institute for Biomedical Research, WSJ-350.3.15
Basel
CH, 4002
Switzerland


Yuko Tsutsui
Department of Physiology & Biophysics
Case Western Reserve University
Cleveland
Ohio , 44106
USA


Patrick L. Wintrode
Department of Physiology & Biophysics
Case Western Reserve University
Cleveland
Ohio , 44106
USA


Saher Afshan Shaikh
Beckman Institute
Urbana
IL
USA


Tarun Jain
Daiichi Sankyo India Pharma Pvt. Ltd., Gurgaon
Haryana
India


Gurvisha Sandhu
Leadinvent, Delhi University South Campus
New Delhi
India


Anjali Soni
Department of Chemistry & Supercomputing Facility for Bioinformatics & Computational Biology
IIT Delhi
India


Bhyravabhotla Jayaram
Department of Chemistry & Supercomputing Facility for Bioinformatics & Computational Biology & School of Biological Sciences
Indian Institute of Technology, Hauz Khas
New Delhi , 110016
India


Leena Gupta
Division of Medicinal and Process Chemistry
Central Drug Research Institute
Lucknow, 226001
India


Archna Talwar
Department of Chemistry
Isabella Thouborn P.G College
Lucknow, 226001
India


P.M.S. Chauhan
Division of Medicinal and Process Chemistry
Central Drug Research Institute,
Lucknow, 226001
India


Vaijayanti A. Kumar
Organic Chemistry Division National Chemical Laboratory
Pune , 411008
India


Catalina Alarcón de la Lastra
Departamento de Farmacología, Facultad de Farmacia
Universidad de Sevilla
Spain


Isabel Villegas Lama
Departamento de Farmacología, Facultad de Farmacia
Universidad de Sevilla
Spain


Marina Sánchez-Fidalgo
Departamento de Farmacología, Facultad de Farmacia
Universidad de Sevilla
Spain




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