Editor: "José R.-Herrera"

Dimorphic Fungi: Their Importance as Models for Differentiation and Fungal Pathogenesis

Personal Book: US $34 Special Offer (PDF + Printed Copy): US $136
Printed Copy: US $119
Library Book: US $136
ISBN: 978-1-60805-510-4
eISBN: 978-1-60805-364-3 (Online)
DOI: 10.2174/97816080536431120101

Introduction

Dimorphism can be defined as the property of different fungal species to grow in the form of budding yeasts or in the form of mycelium, depending on the environmental conditions. Dimorphism may be considered as a differentiative phenomenon, similar to others exhibited by fungi: spore germination, sporulation, etc, but comparatively simple to analyze.

Fungal dimorphism involves extensive changes in the cell physiology and morphology in response to external signals, producing drastic alterations in the cell wall structure and synthesis, whose growth pattern changes from isodiametric (spherical) to polarized or vice versa. Because of this, dimorphism has been the subject of extensive studies as a model for the differentiation processes occurring in eukaryotic organisms.

Additionally, it is important to recall that the most important human pathogenic fungi, and some plant pathogenic ones are dimorphic, displaying different morphologies when growing as saprophytes, or inside their hosts. This observation, and the demonstration that mutants in specific genes that interfere with the dimorphic transition are non-virulent, has suggested that this process might be a target for efficient antimycotic drugs.

This e-book includes several chapters on the most important and studied fungal models, written by specialists, discussing the biology of each species or genera, the general aspects controlling their dimorphic transition, the molecular aspects involved, the use of them as models for understanding the bases of biochemical and cell differentiation, and the importance of dimorphism in pathogenesis.

This e-book is recommended for scholars and researchers working or interested in human, animal and plant pathogenesis, fungal genetics, molecular biology, development, evolution, and differentiation.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, Scopus, EBSCO.

Contributors

Editor(s):
José R.-Herrera
Unidad Irapuato
Centro de Investigación y de Estudios Avanzados
del IPN
Irapuato
Gto.
México




Contributor(s):
E. Campos-Góngora
Departamento de Ingeniería Genética
Unidad Irapuato
Centro de Investigación y de Estudios Avanzados del IPN1

/
Centro de Investigación en Nutrición y Salud Pública
Universidad Autónoma de Nuevo León2
Monterrey, NL México
Km. 9.6 Libramiento Norte Carretera Irapuato-León
Apartado Postal 629



E. Calabrese
Dept. of Pharmaceutical and Biomedical Science
University of Salerno
Italy


MV. Deshpande
Biochemical Sciences Division
National Chemical Laboratory
Pune, 411008
India


V. Ghormade
Centre for Nanobioscience
Agharkar Research Institute
Pune, 411004
India


I. Granata
Dept. of Pharmaceutical and Biomedical Science
University of Salerno
Italy


M de la L. Guerrero-González
División de Biología Molecular
Instituto Potosino de Investigación Cientifica y Tecnológica (IPICYT)
San Luis Potosí
México
/
Camino a la Presa de San José 2055
Apartado Postal 3-74 Tangamanga
San Luis Potosí, SLP, C.P. 78216
México


JF. Jiménez-Bremont
División de Biología Molecular
Instituto Potosino de Investigación Cientifica y Tecnológica (IPICYT)
San Luis Potosí
México
/
Camino a la Presa de San José 2055
Apartado Postal 3-74 Tangamanga
San Luis Potosí, SLP, C.P. 78216
México


CG. León-Ramírez
Departamento de Ingeniería Genética
Unidad Irapuato. Centro de Investigación y de Estudios Avanzados del IPN
México
/
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
Km. 9.6 Libramiento Norte Carretera Irapuato-León
Apartado Postal 629



LM. Lopes-Bezerra
Laboratory of Cellular Mycology and Proteomics
Biology Institute, State University of Rio de Janeiro (UERJ)
Rua São Francisco Xavier 524 PHLC
Rio de Janeiro, 20550-013
Brazil


B. Maresca
Dept. of Pharmaceutical and Biomedical Science
University of Salerno
Italy


RC. Nascimento
Laboratory of Cellular Mycology and Proteomics
Biology Institute, State University of Rio de Janeiro (UERJ)
Rua São Francisco Xavier 524 PHLC
Rio de Janeiro, 20550-013
Brazil


G. Niño-Vega
Laboratorio de Micología, Centro de Microbiología y Biología Celular
Instituto Venezolano de Investigaciones Científicas (IVIC)
Apartado 20632
Caracas, 1020A
Venezuela


E. Pathan
Biochemical Sciences Division
National Chemical Laboratory
Pune, 411008
India


AA. Rodríguez-Hernández
División de Biología Molecular
Instituto Potosino de Investigación Cientifica y Tecnológica (IPICYT)
San Luis Potosí
México
/
Camino a la Presa de San José 2055
Apartado Postal 3-74 Tangamanga
San Luis Potosí, SLP, C.P. 78216
México


M. Rodríguez-Kessler
Facultad de Ciencias
Universidad Autónoma de San Luis Potosí
México
/
Av. Salvador Nava s/n
Zona Universitaria
San Luis Potosí, SLP, C.P. 78290
México


J. Ruiz-Herrera
Departamento de Ingeniería Genética
Unidad Irapuato. Centro de Investigación y de Estudios Avanzados del IPN
México
/
Km. 9.6 Libramiento Norte Carretera Irapuato-León
Apartado Postal 629



G. San-Blas
Laboratorio de Micología, Centro de Microbiología y Biología Celular
Instituto Venezolano de Investigaciones Científicas (IVIC)
Apartado 20632
Caracas, 1020A
Venezuela




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