Editor: "Kuldip S. Sidhu"

Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside

Personal Book: US $89 Special Offer (PDF + Printed Copy): US $163
Printed Copy: US $119
Library Book: US $356
ISBN: 978-1-60805-533-3
eISBN: 978-1-60805-289-9 (Online)
DOI: 10.2174/97816080528991120101

Introduction

Pluripotent stem cells have garnered tremendous interest in recent years, which is primarily driven by the hope of finding a cure for several debilitating human diseases. Cell transplantation (regeneratve medicine) offers considerable therapeutic potential. The procedure employs pluripotent stem cells as these have the inherent ability to reproduce indefinitely and have the ability to produce over 200 different types of cells constituting the human body. The isolation of human embryonic stem cells (hESCs) from embryos and their successful culture in a petri dish in 1998 has been considered as a major breakthrough that is set to shape stem cell research in the 21st century. This has been followed by another remarkable breakthrough in 2006 when scientists demonstrated for the first time that such pluripotent stem cells could be produced from adult somatic tissues without having to use human embryos. These pluripotent stem cells are called the induced pluripotent stem (iPS) cells. Both hESCs and iPS cells - highly versatile cells – could pave the way for alleviating patients suffering from diabetes, Parkinson’s disease, Alzheimer’s disease, and many more.

This eBook brings together the information from the last decade on stem cells, compiled by reputed research experts. Readers will learn all aspects of pluripotent stem cells from basic biology to their use in understanding disease process, toxicology, drug discovery and in developing therapeutic strategies. Research on these cells, including transitional and translational aspects, is explained with the aid of extensive figures, colour photographs, and tables.

This eBook is a valuable resource for undergraduates, postgraduates, scientists, embryologists, tissue engineers, doctors and biomedical scientists interested in stem cell research and medicine.

Indexed in: Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, Scopus, EBSCO.

Contributors

Editor(s):
Kuldip S. Sidhu
The University of New South Wales
Australia




Contributor(s):
Susanne B.-Hoffman
In Vitro Methods Unit (ECVAM)
Institute for Health & Consumer
Protection Joint Research Centre
European Commission via E. Fermi
Ispra (VA)
Italy


Romulo M. Brena
Epigenome Center
Norris Comprehensive Cancer Center
University of Southern California
1450 Biggy Street, NRT G511
Los Angeles
CA 90033-9601
USA


Sven Büttner
Alzheimer’s &; Parkinson’s Disease Lab
Brain & Mind Research Institute
University of Sydney
Sydney

Australia


H. Cao
College of Veterinary Medicine
Shaanxi Center of Stem Cell Engineering & Technology
Northwest A&F University
Yangling
Shaanxi
China


Methichit Chayosumrit
Siriraj Center of Excellence for Stem Cell Research
Faculty of Medicine, Siriraj Hospital
Mahidol University
Thailand


Henry Chung
Stem Cell Lab
Faculty of Medicine
The University of New South Wales
Sydney
Australia


Taraprasad Das
L V Prasad Eye Institute
Bhubaneswar Campus
Orissa
India


Mark Denham
Centre for Neuroscience
Department of Pharmacology
The University of Melbourne
Australia


Mirella Dottori
Centre for Neuroscience
Department of Pharmacology
The University of Melbourne
Melbourne
Australia


Roberto E.-Waser
In Vitro Methods Unit (ECVAM)
Institute for Health & Consumer
Protection Joint Research Centre
European Commission via E. Fermi
Ispra
(VA)
Italy


Subhash Gaddipati
L.V.Prasad Eye Institute
Kallam Anji Reddy Campus
L.V.Prasad Marg, Banjara Hills
Hyderabad
India


Jürgen Götz
Alzheimer’s & Parkinson’s Disease Lab
Brain & Mind Research Institute
University of Sydney
Sydney
Australia


Anand Hardikar
Diabetes and Pancreas Biology Section
The O'Brien Institute, Department of Surgery
St Vincent's Hospital
The University of Melbourne
Australia


Y. Hu
College of Veterinary Medicine
Shaanxi Center of Stem Cell Engineering & Technology
Northwest A&F University
Yangling
Shaanxi
China


Jinlian Hua
College of Veterinary Medicine
Shaanxi Center of Stem Cell Engineering & Technology
Northwest A&F University
Yangling
Shaanxi
China


Brock James
Centre for Neuroscience
Department of Pharmacology
The University of Melbourne
Australia


Martina Klaric
In Vitro Methods Unit (ECVAM)
European Commission via E. Fermi
Protection Joint Research Centre
Institute for Health & Consumer
Ispra
(VA)
Italy


Khun H. Lie
Stem Cell Lab
Faculty of Medicine
University of New South Wales
Australia


Robert Lindeman
Department of Haematology
Prince of Wales Hospital
Barker Street
Randwick
NSW 2031
Australia


Zichuan Liu
State Key Lab of Reproductive Biology
Institute of Zoology
Chinese Academy of Sciences
Graduate School of Chinese Academy of Sciences
Beijing
P R
China


David Ma
Blood Stem Cells and Cancer Research
St Vincent's Centre for Applied Medical Research
St Vincent's Hospital
Darlinghurst
NSW 2010
Australia


Indumathi Mariappan
L.V.Prasad Eye Institute
Kallam Anji Reddy Campus
L.V.Prasad Marg, Banjara Hills
Hyderabad
India


Michael Morris
School of Medical Sciences
Bosch Institute
Royal North Shore Hospital
The University of Sydney
Sydney
Australia


Catalina A. Palmer
Blood Stem Cells and Cancer Research
St Vincent's Centre for Applied Medical Research
St Vincent's Hospital
Darlinghurst
NSW 2010
Australia


Martin Pera
The Eli and Edythe Broad Center
Regenerative Medicine and Stem Cell Research
USC
USA


Perminder Sachdev
Neuropsychiatry Institute
The University of New South Wales
Sydney
Australia


Virender Sangwan
L.V.Prasad Eye Institute
Kallam Anji Reddy Campus
L.V.Prasad Marg, Banjara Hills
Hyderabad
India


Kuldip S. Sidhu
Faculty of Medicine
The University of New South Wales
Sydney
Australia


Loane Skene
Melbourne Law School
University of Melbourne
Parkville
Melbourne
Australia 3010


J. Sun
College of Veterinary Medicine
Shaanxi Center of Stem Cell Engineering & Technology Northwest
A &F University Yangling
Shaanxi
China


Greg Sutherland
Discipline of Pathology
Sydney Medical School
University of Sydney
Sydney
Australia


Geeta Vemuganti
L.V.Prasad Eye Institute
Kallam Anji Reddy Campus
L.V.Prasad Marg, Banjara Hills
Hyderabad
India


Kinga Vojnits
In Vitro Methods Unit (ECVAM)
Institute for Health & Consumer
Protection Joint Research Centre
European Commission via E. Fermi
Ispra
(VA)
Italy


L. Wang
College of Veterinary Medicine
Shaanxi Center of Stem Cell Engineering& Technology
Northwest A&F University
Yangling
Shaanxi
China


Baolong Xia
State Key Lab of Reproductive Biology
Institute of Zoology
Chinese Academy of Sciences
Graduate School of Chinese Academy of Sciences
Beijing
P R. China


Shun Zhang
State Key Lab of Reproductive Biology
Institute of Zoology
Chinese Academy of Sciences
Graduate School of Chinese Academy of Sciences
Beijing
P R
China


S. Zhang
College of Veterinary Medicine
Shaanxi Center of Stem Cell Engineering & Technology
Northwest A&F University
Yangling
Shaanxi
China


Qi Zhou
State Key Lab of Reproductive Biology
Institute of Zoology
Chinese Academy of Sciences
Beijing
P R
China


Shuya Zhou
State Key Lab of Reproductive Biology
Institute of Zoology
Chinese Academy of Sciences
Graduate School of Chinese Academy of Sciences
Beijing
P R
China


H. Zhu
College of Veterinary Medicine
Shaanxi Center of Stem Cell Engineering & Technology
Northwest A&F University
Yangling
Shaanxi
China




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