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Frontiers in Medicinal Chemistry
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Frontiers in Medicinal Chemistry

Volume 5
eBook: US $44 Special Offer (PDF + Printed Copy): US $237
Printed Copy: US $215
Library License: US $176
ISSN: 1567-2042 (Print)
ISSN: 1875-5763 (Online)
ISBN: 978-1-60805-675-0 (Print)
ISBN: 978-1-60805-208-0 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080520801100501
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Introduction

Frontiers in Medicinal Chemistry is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. “Frontiers in Medicinal Chemistry” covers all the areas of medicinal chemistry, including developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships.

Medicinal chemistry as a discipline is rapidly maturing. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. “Frontiers in Medicinal Chemistry” aims to contribute in a major way to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. This Ebook series is essential for any medicinal chemist who wishes to be kept informed and up-to-date with the latest and the most important advances.

Indexed in

EMBASE, Scopus, Genamics JournalSeek, EMBiology

Indexed in: Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, Scopus, EMBASE, Chemical Abstracts, Scilit, EBSCO, Ulrich's Periodicals Directory.


eBook: US $44 Special Offer: US $237 Printed Copy: US $215 Library License: US $176

Contributors

Co-Editor(s):
Atta-ur-Rahman
Biological Sciences
(HEJ Research Institute of Chemistry, Dr. Panjwani Center for Molecular, Medicine & Drug Research)
University of Karachi
Karachi, 75270
Pakistan


Allen B. Reitz
Johnson & Johnson Pharmaceutical Research and Development, Spring House
Pennsylvania , 19477
USA


M. Iqbal Choudhary
Biological Sciences
(HEJ Research Institute of Chemistry, Dr. Panjwani Center for Molecular, Medicine & Drug Research)
University of Karachi
Karachi, 75270
Pakistan



Editorial Advisory Board:
P.R. Bernstein
University of Delaware
Newark
DE
USA


C. Bor-Luen
National Taiwan University, Taipei
Taiwan
R.O.C.


R. Efremov
M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry
Moscow
Russia


C. Garcia-Echeverria
Sanofi-Aventis
Paris
France


D. Hadjipavlou-Litina
Arristotle Universith of Thessaloniki
Thessaloniki
Greece


D. Heymann
University of Nantes
Nantes
France


D.A. Jans
Nuclear Signaling Laboratory, Monash University
Australia


G.B. Mahady
University of Illinois at Chicago
Chicago
IL
USA


B. Malawska
Jagiellonian University Collegium Medicum
Kraków
Poland


C. Philippe
Sciences and Technologies University of Lille
Lille
France



Contributor(s):
Jeroen J.M. Hoozemans
Neurogenetics Laboratory
Amsterdam
The Netherlands


Sidhartha M. Chafekar
Neurogenetics Laboratory
Amsterdam
The Netherlands


Frank Baas
Neurogenetics Laboratory, Department of Neurology
Academic Medical Center, University of Amsterdam
Amsterdam
The Netherlands


Piet Eikelenboom
Department of Neurology, Academic Medical Center
University of Amsterdam
Amsterdam
The Netherlands


Wiep Scheper
Neurogenetics Laboratory
Amsterdam
The Netherlands


Kirubakaran Shanmugam
Department of Pharmacology
School of Medicine, University of Western Sydney
Campbelltown
Australia


Annette E. Maczurek
Department of Pharmacology
School of Medicine, University of Western Sydney
Campbelltown
Australia


Megan L. Steele
Department of Pharmacology
School of Medicine, University of Western Sydney
Campbelltown
Australia


Obdulio Benavente-García
Furfural Español-Nutrafur
Alcantarilla
Murcia
Spain


Julián Castillo
Furfural Español-Nutrafur
Alcantarilla
Murcia
Spain


Gerald Münch
Department of Pharmacology,
School of Medicine, University of Western Sydney
Campbelltown
Australia


Arjan Blokland
Department of Psychology and Neuroscience
EURON, Maastricht University
P.O. Box 616
Maastricht
MD , 6200
The Netherlands


Rudy Schreiber
Sepracor, Inc.
84 Waterford Drive
Marlborough
MA, 01752
USA


Jos Prickaerts
Department of Psychiatry and Neuropsychology
Brain & Behavior Institute, EURON, Maastricht University
P.O. Box 616
Maastricht
MD , 6200
The Netherlands


Yoko Shoji-Moskowitz
CREST, JAPAN;FOLIGO Therapeutics, Inc.
USA


Daisuke Asai
CREST, JAPAN; Department of Microbiology, Department of Biomedical Engineering
St. Marianna University School of Medicine, Japan
Duke University
USA


Kota Kodama
CREST, JAPAN;FOLIGO Therapeutics, Inc.
USA
/
Creative Research Institution
Hokkaido University
Japan


Yoshiki Katayama
CREST, JAPAN; Department of Applied Chemistry
Faculty of Engineering, Kyushu University
Japan


Hideki Nakashima
CREST, JAPAN; Department of Applied Chemistry
Faculty of Engineering, Kyushu University
Japan


Kylie M. Wagstaff
Nuclear Signalling Laboratory, Department of Biochemistry and Molecular Biology
Monash University
Clayton
Australia


David A. Jans
ARC Centre of Excellence for Biotechnology and Development
Australia


Geoffrey A. Pietersz
Bio-organic and Medicinal Chemistry Laboratory
Australia


Dodie S. Pouniotis
Immunology and Vaccine Laboratory
Centre for Immunology, Burnet Institute
Commercial Road, Melbourne
Szeged
VIC, 3004
Australia


Vasso Apostolopoulos
Immunology and Vaccine Laboratory
Centre for Immunology, Burnet Institute
Commercial Road, Melbourne
Szeged
VIC, 3004
Australia


Farid El Oualid
Netherlands Cancer Institute
Division of Cell Biology
Amsterdam
1066 , CX
The Netherlands


Gijs A. van der Marel
Leiden Institute of Chemistry, Gorlaeus Laboratories
Leiden University
P.O. Box 9502
Leiden
RA, 2300
The Netherlands


Mark Overhand
Leiden Institute of Chemistry, Gorlaeus Laboratories
Leiden University
P.O. Box 9502
Leiden
RA, 2300
The Netherlands


Ludovic Gillet
U921 Inserm, Nutrition Croissance Cancer
Université de Tours; Faculté de Médecine
10 Bd Tonnellé
TOURS , 37032
France


Sébastien Roger
U921 Inserm, Nutrition Croissance Cancer
Université de Tours; Faculté de Médecine
10 Bd Tonnellé
TOURS , 37032
France


Marie Potier
U921 Inserm, Nutrition Croissance Cancer
Université de Tours; Faculté de Médecine
10 Bd Tonnellé
TOURS , 37032
France


Lucie Brisson
U921 Inserm, Nutrition Croissance Cancer
Université de Tours; Faculté de Médecine
10 Bd Tonnellé
TOURS , 37032
France


Christophe Vandier
U921 Inserm, Nutrition Croissance Cancer
Université de Tours; Faculté de Médecine
10 Bd Tonnellé
TOURS , 37032
France


Pierre Besson
U921 Inserm, Nutrition Croissance Cancer
Université de Tours; Faculté de Médecine
10 Bd Tonnellé
TOURS , 37032
France


Jean-Yves Le Guennec
U921 Inserm, Nutrition Croissance Cancer
Université de Tours; Faculté de Médecine
10 Bd Tonnellé
TOURS , 37032
France


Kyuichi Tanikawa
President, International Institute for Liver Research
Kurume University, Alley II 202
Tsubuku-honmachi 636-1
Kurume , 830-0047
Japan


Alma Martelli
Dipartimento di Psichiatria, Neurobiologia
Farmacologia e Biotecnologie,Università degli Studi di Pisa
Via Bonanno, 6
Pisa, I-56126
Italy


Simona Rapposelli
Dipartimento di Scienze Farmaceutiche
Università degli Studi di Pisa,Via Bonanno, 6
Av. de l'Hôpital, 1, B36
Pisa, I-56126
Italy


Maria C. Breschi
Dipartimento di Psichiatria, Neurobiologia
Farmacologia e Biotecnologie,Università degli Studi di Pisa
Via Bonanno, 6
Pisa, I-56126
Italy


Vincenzo Calderone
Dipartimento di Psichiatria, Neurobiologia
Farmacologia e Biotecnologie,Università degli Studi di Pisa
Via Bonanno, 6
Pisa, I-56126
Italy


Katarzyna Kulig
Department of Physicochemical Drug Analysis, Chair of Pharmaceutical Chemistry
Jagiellonian University Medical College
Medyczna 9 str.
Kraków
FL, 30-688
Poland


Barbara Malawska
Department of Physicochemical Drug Analysis, Chair of Pharmaceutical Chemistry
Jagiellonian University Medical College
Medyczna 9 str.
Kraków
FL, 30-688
Poland


Trond Ulven
Department of Physics and Chemistry
University of Southern Denmark
Campusvej 55, DK-5230 Odense M
Denmark


Evi Kostenis
Institute for Pharmaceutical Biology, University of Bonn
Nussallee 6, PO Box 100485
Bonn, 53115
Germany


Luca Costantino
Dipartimento di Scienze Farmaceutiche, Via Campi 183
University of Modena e Reggio Emilia
Modena, 41100
Italy


Daniela Barloccob
Dipartimento di Scienze Farmaceutiche “Pietro Pratesi”
Via L. Mangiagalli 25, University of Milano
Milano, 20133
Italy


Gerald H. Lushington
Molecular Graphics and Modeling Laboratory
University of Kansas
Lawrence
KS , 66045
USA


Jian-Xin Guo
Molecular Graphics and Modeling Laboratory
University of Kansas
Lawrence
KS , 66045
USA


Margaret M. Hurley
Weapons and Materials Research Directorate
U.S. Army Research Laboratory
Aberdeen Proving Ground
MD , 21005
USA



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