Editors: Elisabetta Tosti, Raffaele Boni

Oocyte Maturation and Fertilization: A long history for a short event

Special Offer (PDF + Printed Copy): US $119
Printed Copy: US $119
ISBN: 978-1-60805-062-8 (Print)
ISBN: 978-1-60805-182-3 (Online)
Year of Publication: 2011
DOI: 10.2174/97816080518231110101


Events of reproduction occurring from meiotic resumption of the immature oocyte up to its exit from the second meiotic block following activation will be revealed. Morphological modifications of the oocyte during maturation will be related to signal transduction mechanisms involving primary or secondary messengers. A detailed view will be addressed to genetic and epigenetic control of oocyte maturation. At fertilization, reciprocal gamete activation and novel knowledge related to sperm factor and cascade mechanisms occurring in the oocyte will be focused. A detailed description of ion currents occurring during fertilization will depict another point of view of oocyte activation mechanisms, further supporting for their complexity.

Finally, all basic information related to this short time lapse will be considered in relation to clinical application of assisted reproductive technologies. New frontiers, such as stem cells and cloning technologies, will be analyzed and future applications and improvements will be hypothesised.

Indexed in: Chemical Abstracts, EBSCO.


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