Frontiers in Cardiovascular Drug Discovery
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Editors: Atta-ur-Rahman, Dr. M.Iqbal Choudhary

Frontiers in Cardiovascular Drug Discovery

Volume 1

eBook: US $44 Special Offer (PDF + Printed Copy): US $177
Printed Copy: US $155
Library License: US $176
ISSN: 2452-3267 (Print)
ISSN: 1879-6648 (Online)
ISBN: 978-1-60805-668-2 (Print)
ISBN: 978-1-60805-160-1 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080516011100101

Introduction

“Frontiers in Cardiovascular Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Cardiovascular drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in cardiovascular drug design and discovery. Each volume is devoted to the major advances in cardiovascular drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Indexed in: Scopus, Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, EMBASE, Chemical Abstracts, EBSCO.

Preface

- Pp. i
Atta-ur-Rahman and M. Iqbal Choudhary
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Contributors

- Pp. ii-vii (6)
Atta-ur-Rahman and M. Iqbal Choudhary
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Statins in Hypertension

- Pp. 1-11 (11)
Carlos A. Feldstein
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New Insights into Pharmacogenetics of Statins Therapy

- Pp. 12-31 (20)
Luca Puccetti, Maurizio Acampa, Marcello Pastorelli, Vittoria Soldati, Francesca Scarpini and Alberto Auteri

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HDL Elevation and Lipid Lowering Therapy: Current Scenario and Future Perspectives

- Pp. 32-60 (29)
Mahesh T. Chhabria, Bhanubhai N. Suhagia and Pathik S. Brahmkshatriya

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New Approaches to Atherosclerotic Cardiovascular Disease: The Potential of Torcetrapib

- Pp. 61-72 (12)
Jose Luis Perez-Castrillon and Antonio Duenas-Laita

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Role of Infrasound Pressure Waves in Atherosclerotic Plaque Rupture: A Theoretical Approach

- Pp. 73-78 (6)
Athanasios Tsatsaris, Efstathios Koukounaris, Theodoros Motsakos and Despina Perrea

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Advances in the Perioperative Management of Pulmonary Hypertension

- Pp. 79-95 (17)
Harish Ramakrishna

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The Role of Small, Dense LDL in Cardiovascular Risk: The Contributions of the Universities of Palermo and Zurich

- Pp. 96-104 (9)
Manfredi Rizzo and Kaspar Berneis

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Role of Omega-3 Fatty Acids in Cardiovascular Disease Prevention

- Pp. 105-120 (16)
GianLuca Colussi, Cristiana Catena, Elisa Nadalini, Alessandra Chiuch, Alessandro Di Fabio, Marica Valeri and Leonardo A. Sechi

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Chronic Diabetic Complications: Endothelial Cells at the Frontline

- Pp. 121-137 (17)
Zia A. Khan and Subrata Chakrabarti

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Oxidative Stress in Cardiovascular Disease: A New Avenue Toward Future Therapeutic Approaches

- Pp. 138-153 (16)
Reiko Inagi
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The Clinical Impact of Hyperphosphatemia in Chronic Kidney Disease Patients: The Role of Lanthanum Carbonate

- Pp. 154-164 (11)
Mario Cozzolino and Diego Brancaccio

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Myocardial Protection Against Ischemia-Reperfusion Injury: Novel Approaches in Maintaining Homeostatic Stability in Blood

- Pp. 165-191 (27)
Maqsood M. Elahi and Bashir M. Matata

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The Role of Angiotensin Type 1 Receptor in Inflammation and Endothelial Dysfunction: Clinical Application

- Pp. 192-200 (9)
Dana Skultetyova, Adriena Sakalova, Pavol Chnupa and Slavomira Filipova

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B-Type Natriuretic Peptide for Diagnosis and Therapy

- Pp. 201-211 (11)
Marek Jankowski

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Urokinase-An Important Anti-Thromboembolic Drug

- Pp. 212-235 (24)
Adinarayana Kunamneni, Bhavani D. Ravuri, Vinjamuri Saisha, Poluri Ellaiah and Taadimalla Prabhakhar

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Anti-Inflammatory Effects of Endothelin Receptor Antagonists and their Importance for Treating Human Disease

- Pp. 236-258 (23)
Matthias Barton, Philipp C. Nett, Kerstin Amann and Mauro M. Teixeira

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Levosimendan in Heart Failure

- Pp. 259-269 (11)
Charalambos Antoniades, Michael Demosthenous, Dimitris Tousoulis, Costantinos Bakogiannis, Nikolaos Koumallos and Christodoulos Ste

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Thyroid Hormone in Heart Failure: Potential Therapeutic Implications

- Pp. 270-287 (18)
Alessandro Pingitore and Giorgio Iervasi

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Skeletal Muscle Derived Stem Cells for Myocardial Repair

- Pp. 288-306 (19)
Husnain K. Haider, Lei Ye and Muhammad Ashraf

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A Practical Approach to Diagnosis and Treatment of Symptomatic Thromboembolic Events in Children with Acute Lymphoblastic Leukem

- Pp. 307-323 (17)
Paola Giordano, Giovanni Carlo Del Vecchio, Paola Saracco, Marco Zecca, Angelo Claudio Molinari and Domenico De Mattia

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Recent Progress in Pharmacological Research of Antioxidants in Pathological Conditions: Cardiovascular Health

- Pp. 324-346 (23)
Milagros Rocha, Remedios Garcia-Bou, Raul Herance, Antonio Hernandez-Mijares and Victor M. Victor

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Author Index

- Pp. 347-348 (2)
Atta-ur-Rahman and M. Iqbal Choudhary
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