Editors: Atta-ur-Rahman, Dr. M.Iqbal Choudhary

Frontiers in Cardiovascular Drug Discovery

Volume 1

eBook: US $44 Special Offer (PDF + Printed Copy): US $177
Printed Copy: US $155
Library License: US $176
ISSN: 2452-3267 (Print)
ISSN: 1879-6648 (Online)
ISBN: 978-1-60805-668-2 (Print)
ISBN: 978-1-60805-160-1 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080516011100101


“Frontiers in Cardiovascular Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Cardiovascular drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in cardiovascular drug design and discovery. Each volume is devoted to the major advances in cardiovascular drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.


Recent advances in drug discovery and development are based on post-genomic understanding of human diseases at the cellular as well as molecular levels. Cardiovascular disorders are among the most important group of diseases which have gone through major transformation, both in approach and techniques. The chapters contain in this volume are the updated version of articles published in Recent Patents on Cardiovascular Drug Discovery. This volume comprises well-written reviews contributed by experts in the field of cardiovascular drug discovery and development. Each review summarizes cutting edge researches on a specific approach in CVD treatment. Many of these reviews are focused on the development of various classes of chemical compounds for cardiovascular disease management by interfering in the molecular mechanisms, which lead to atherosclerosis and hypertension.

Most reviews in this volume are written in a way to first introduce the topic and then gradually summarize the important developments in the field in a chronological manner. Thus each review should be of interest not only to professional scientists but also to research students. The references in each review are up-to-date, and represent state-of-the-art developments.

We are grateful to all contributors for their willingness to write short reviews on important aspects of cardiovascular drug discovery and development, as well as, submitting their articles in a timely manner. We are also grateful to the staff of Bentham Science Publishers, especially Mr. Mahmood Alam (Managing Director), Ms. Samina Khan (Senior Manager), Ms. Taqdees Malik (Assistant Manager) and Ms. Sadaf Idrees Khan (Composer), for their untiring efforts to make this assignment a success.

Prof. Dr. Atta-ur-Rahman, FRS
Prof. Dr. M. Iqbal Choudhary