Editors: Karoly Tihanyi , Monika Vastag

Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates

eBook: US $89 Special Offer (PDF + Printed Copy): US $163
Printed Copy: US $119
Library License: US $356
ISBN: 978-1-60805-619-4 (Print)
ISBN: 978-1-60805-120-5 (Online)
Year of Publication: 2011
DOI: 10.2174/97816080512051110101

Introduction

This comprehensive ebook covers all the aspects of ADME/PK modeling including solubility, absorption, formulation, metabolic stability, drug-drug interaction potential and a special delivery tool of drug candidates. The book provides an integrated view of fundamental ADME issues and challenges in early drug development from the aspect of practicing drug researchers. It also provides valuable help for the medicinal chemist in the process of multiple optimization.

Indexed in: Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, Scopus, Chemical Abstracts, EBSCO.

Contributors

Editor(s):
Karoly Tihanyi
Pharmacology and Drug Safety
Gedeon Richter Plc.
Hungary


Monika Vastag
Pharmacology and Drug Safety
Gedeon Richter Plc.
Hungary




Contributor(s):
O. Balázs
Pharmacology and Drug Safety
Gedeon Richter Plc. Budapest 10, H-1475, P.O.B. 27
Hungary


G.T. Balogh
Discovery Chemistry
Gedeon Richter Plc. Budapest 10, H-1475, P.O.B. 27
Hungary


M.A. Deli
Biological Research Center
Hungarian Academy of Sciences
H-6726 Szeged, Temesvári krt. 62.
Hungary


E. Duda
Dept. Medical Biology
University of Szeged
H-6720 Szeged, Dugonics tér.13.
Hungary


A.S. Halász
Pharmacology and Drug Safety
Gedeon Richter Plc. Budapest 10, H-1475, P.O.B. 27
Hungary


É. Hellinger
Pharmacology and Drug Safety
Gedeon Richter Plc. Budapest 10, H-1475, P.O.B. 27
Hungary


K. Herédi-Szabó
SOLVO Biotechnology
Central Hungarian Innovations Center
H-2040 Budaörs, Gyár u. 2.
Hungary


E. Ioja
SOLVO Biotechnology
Central Hungarian Innovations Center
H-2040 Budaörs, Gyár u. 2.
Hungary


J. Jánossy
SOLVO Biotechnology
Central Hungarian Innovations Center
H-2040 Budaörs, Gyár u. 2.
Hungary


V. Juhász
SOLVO Biotechnology
Central Hungarian Innovations Center
H-2040 Budaörs, Gyár u. 2.
Hungary


G.M. Keserü
Discovery Chemistry
Gedeon Richter plc. Budapest 10, H-1475, P.O.B. 27
Hungary


Á. Kittel
Hungarian Academy of Sciences
Institute of Experimental Medicine
H-1450 Budapest, P.O.B. 67.
Hungary


P. Krajcsi
SOLVO Biotechnology
Central Hungarian Innovations Center
H-2040 Budaörs, Gyár u. 2.
Hungary


T. Letoha
Biological Research Center
Hungarian Academy of Sciences
H-6726 Szeged, Temesvári krt. 62.
Hungary


L. Molnár
Discovery Chemistry
Gedeon Richter plc. Budapest 10, H-1475, P.O.B. 27.
Hungary


Z. Nagy
SOLVO Biotechnology
Central Hungarian Innovations Center
H-2040 Budaörs, Gyár u. 2
Hungary


B. Noszál
Department of Pharmaceutical Chemistry
H-1092 Budapest, Hőgyes E. u. 9.
Hungary


G. Orgován
Department of Pharmaceutical Chemistry
H-1092 Budapest, Hőgyes E. u. 9.
Hungary


K. Tihanyi
Pharmacology and Drug Safety
Gedeon Richter Plc. Budapest 10, H-1475, P.O.B. 27.
Hungary


M. Vastag
Pharmacology and Drug Safety
Gedeon Richter Plc. Budapest 10, H-1475, P.O.B. 27.
Hungary


S. Veszelka
Biological Research Center, Hungarian Academy of Sciences
H-6726 Szeged, Temesvári krt. 62.
Hungary




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