Network Approaches to Diseases of the Brain


Matt T. Bianchi, Verne S. Caviness, Sydney S. Cash

DOI: 10.2174/97816080501781120101
eISBN: 978-1-60805-017-8, 2012
ISBN: 978-1-60805-380-3

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, Scopus, EBSCO.

This book covers novel approaches using networks and oscillations and it will serve as a catalyst for translating these exciting advan...[view complete introduction]
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Brain Anatomy and Small-World Networks

- Pp. 32-50 (19)

Danielle S. Bassett and Edward T. Bullmore


Network analysis of neural and other information-processing systems has recently provided unique insights into the large-scale cohesive organization of subcomponents at many scales of space and time. In this chapter, we describe the network analysis of neural systems in general and that of the healthy and diseased human brain in particular. We present evidence from a variety of species and data modalities that neural systems show the so-called ”small-world” network phenomenon which also ubiquitously characterizes social groups, scientific collaborations, the world wide web, transportation networks, power grids, etc. We attempt to provide reasons why this property might have been selected in brain evolution, and to explain its functional significance, while delineating the methodological intricacies of network analysis of neuroimaging data.

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