Editor: Javier Camacho

Molecular Oncology: Principles and Recent Advances

eBook: US $79 Special Offer (PDF + Printed Copy): US $158
Printed Copy: US $119
Library License: US $316
ISBN: 978-1-60805-611-8 (Print)
ISBN: 978-1-60805-016-1 (Online)
Year of Publication: 2012
DOI: 10.2174/97816080501611120101

Introduction

Cancer is one of the major causes of death worldwide. Despite hundreds of clinical trials currently in progress for cancer patients, the success rate is still very low. Understanding the molecular aspects of cancer development, the discovery of new molecular targets and rational drug design on this molecular basis should help in discovering early cancer biomarkers as well as novel therapeutic drugs.

This book describes various cancer topics on a molecular level and integrates information on the relationship between causes of cancer, cancer cell biology, metastasis, cancer prevention and drug design. This book should prove to be an extraordinary reference text for students, physicians and oncologists.

Indexed in: Book Citation Index, Science Edition, Scopus, BIOSIS Previews, EBSCO.

Foreword

- Pp. i
Manfred Schwab
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Preface

- Pp. ii
Javier Camacho
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List of Contributors

- Pp. iii-vii (5)
Javier Camacho
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Cell Proliferation, Differentiation and Apoptosis

- Pp. 3-17 (15)
Miriam Huerta, Carla Angulo and Esther López-Bayghen

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I. The Influence of the Environment

- Pp. 18-27 (10)
Andrea De Vizcaya-Ruiz and Araceli Hernandez-Zavala

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II. Obesity and Cancer

- Pp. 28-32 (5)
Ranier Gutierrez

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III. Estrogens and Cancer

- Pp. 33-43 (11)
Jesus Adrian Rodriguez-Rasgado, Flavia Morales-Vasquez, Luz Maria Hinojosa and Javier Camacho

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IV. Example 1: Hepatocellular Carcinoma

- Pp. 44-47 (4)
Pablo Muriel

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V. Example 2: Estrogens, Retinoids and Cervical Cancer Development

- Pp. 48-63 (16)
Jorge Gutiérrez, Enoc Mariano Cortés, José Juan Vázquez and Patricio Gariglio

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Oncogenes and Tumor Suppressor Genes

- Pp. 64-82 (19)
Patricio Gariglio

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Epigenetics of Cancer

- Pp. 83-97 (15)
Claudia M. Garcia-Cuellar and Alfonso Duenas-Gonzalez

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Signal Transduction Pathways in Cancer

- Pp. 98-111 (14)
Lucrecia Marquez-Rosado

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Metastasis

- Pp. 112-129 (18)
Lucrecia Marquez-Rosado

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Cancer Immunology and Novel Strategies for Immunotherapy

- Pp. 130-147 (18)
Alberto Monroy-Garcia, Maria de Lourdes Mora-Garcia and Jorge Hernandez- Montes

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In Vitro and In Vivo Models for Cancer Research

- Pp. 148-162 (15)
Julio Isael Perez Carreon and Jorge Melendez Zajgla

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Molecular Diagnosis and Prognosis

- Pp. 163-171 (9)
M. Veronica Ponce-Castaneda and Lourdes Cabrera-Munoz

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Chemotherapy and Design of New Antineoplastic Compounds

- Pp. 172-191 (20)
Claudia Rivera-Guevara, Maria Elena Bravo-Gomez and Lena Ruiz-Azuara

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Mechanisms of Therapy Resistance in Cancer

- Pp. 192-197 (6)
Ivan Restrepo, Cindy Sharon Ortiz and Javier Camacho

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Antisense Oligodeoxyribonucleotides (AS-ODNs) for Cancer Gene Therapy: A Clinical Perspective

- Pp. 198-218 (21)
Maria Luisa Benitez-Hess and Luis Marat Alvarez-Salas

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Directions of Future Cancer Research

- Pp. 219-222 (4)
Javier Camacho

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Author Index

- Pp. 223
Javier Camacho
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Subject Index

- Pp. 224-227 (4)
Javier Camacho
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