Editor: Massimo Alfano

Soluble Factors Mediating Innate Immune Responses to HIV Infection

eBook: US $69 Special Offer (PDF + Printed Copy): US $153
Printed Copy: US $119
Library License: US $276
ISBN: 978-1-60805-580-7 (Print)
ISBN: 978-1-60805-006-2 (Online)
Year of Publication: 2010
DOI: 10.2174/97816080500621100101

Introduction

Human Immunodeficiency Virus (HIV) infection represents one of the biggest challenges of current years. However, scientists and physicians still do not have an efficient therapy for preventing or eradicating the virus. The selection of drug-resistant strains as well as side-effects, represent common problems encountered in all anti-viral therapies. However, it has been clearly demonstrated that the potency of early immune responses profoundly regulates levels of HIV, and hence also the generation of virus mutants as well as the velocity of disease progression to AIDS.

A prominent feature of this e-book is the focus on interaction between innate immunity and HIV infection. This topic has been investigated by many authors from the late 80's, and many soluble factors responsible for such activity have been discovered, such as suPAR and HMGB1. At present, these two novel factors are the subject of very intense research on HIV infections.

A key advantage of this e-book is the selection of authors, recognized worldwide as leading experts in their field. Because of the comprehensive coverage, as well as the eminence of the authors, this e-book provides a detailed and high quality description about the role of innate immune responses regulating HIV replication. It should prove to be a useful resource for readers interested in immunology and HIV research.

Indexed in: Book Citation Index, Science Edition, BIOSIS Previews, Chemical Abstracts, Scopus, EBSCO.

Contributors

Editor(s):
Massimo Alfano
AIDS Immunopathogenesis Unit
Department of Immunology, Transplantation and Infectious Diseases
San Raffaele Scientific Institute
Milan, 20132
Italy




Contributor(s):
Massimo Alfano
AIDS Immunopathogenesis Unit
Department of Immunology, Transplantation and Infectious Diseases
San Raffaele Scientific Institute
Milan, 20132
Italy


Zoltàn Banki
Department of Hygiene and Medical Microbiology
Innsbruck Medical University
Innsbruck, A-6020
Austria


Chloe Borde
Centre de Recherche des Cordeliers
Universitè Pierre et Marie Curie
Paris, F-75006
France
/
Université Paris Descartes
Paris, F-75006
France
/
INSERM Paris
France


Cynthia L. Bristow
Department of Medicine, Weill Medical College of Cornell University
Institute for Human Genetics and Biochemistry, Laboratory for AIDS Virus Research
New York
NY, 10065
USA


Antonio Caruz
Immunogenetics Unit, Faculty of Sciences
Universidad de Jaén
Pasaje Las Lagunillas s/n 23071
Jaén
Spain


Theresa L. Chang
Department of Medicine, Division of Infectious Diseases
Mount Sinai School of Medicine, Box 1090, One Gustave L. Levy Place
New York
NY, 10029
USA


Jose Cortes
Beth Israel Medical Center
New York
NY, 10003
USA


Jesper Eugen-Olsen
Clinical Research Centre 136
Copenhagen University Hospital Hvidovre Hospital
Hvidovre, 2650
Denmark


Joan Fibla
Human Genetics Unit, Departament de Ciències Mèdiques Bàsiques
Universitat de Lleida and Institut de Recerca Biomèdica de Lleida
Catalunya
LLEIDA, 25199
Spain


Aaron Franklin
University of Toledo College of Medicine
Toledo
OH, 43614
USA


Joel Gozlan
Laboratoire de Virologie
Hôpital Saint-Antoine
Paris, F-75012
France
/
Centre de Recherche des Cordeliers
Université Pierre et Marie Curie
Paris, F-75006
France
/
Universitè Paris Descartes
Paris, F-75006
France
/
INSERM
Paris, F-75006
France


Eva Haastrup
Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet
Copenhagen
Denmark


Mary E. Klotman
Department of Medicine, Division of Infectious Diseases
Mount Sinai School of Medicine, Box 1090, One Gustave L. Levy Place
New York
NY, 10029
USA


Anne Langkilde
Clinical Research Centre 136, Copenhagen University Hospital Hvidovre Hospital
Hvidovre, 2650
Denmark


Katherine Lau
Retroviral Genetics Division Center for Virus Research
Westmead Millennium Institute, Westmead Hospital
Westmead NSW 2145
Sydney
Australia


Vincent Marechal
Centre de Recherche des Cordeliers
Universitè Pierre et Marie Curie
Paris, F-75006
France
/
Université Paris Descartes
Paris, F-75006
France
/
INSERM
Paris, F-75006
France


Roya Mukhtarzad
Kingsbrook Jewish Medical Center, Brooklyn
New York
NY, 11203
USA


Sisse Rye Ostrowski
Department of Clinical Immunology, Rigshospitalet
Copenhagen University Hospital
Copenhagen
Denmark


Guido Poli
Vita-Salute San Raffaele University School of Medicine
San Raffaele Scientific Institute
Milan, 20132
Italy
/
AIDS Immunopathogenesis Unit, Department of Immunology
Transplantation and Infectious Diseases San Raffaele Scientific Institute
Milan, 20132
Italy


Val Romberg
CSL Behring
Bern
CH, 3000
Switzerland


Nitin K. Saksena
Retroviral Genetics Division Center for Virus Research
Westmead Millennium Institute, Westmead Hospital Westmead
Sydney
NSW, 2145
Australia


Maly Soedjono
Retroviral Genetics Division Center for Virus Research, Westmead Millennium Institute, Westmead Hospital, Westmead
Sydney
NSW, 2145
Australia


Heribert Stoiber
Department of Hygiene and Medical Microbiology
Innsbruck Medical University
Innsbruck, A-6020
Austria


Maylis Trucy
Department of Medicine, Weill Medical College of Cornell University
Institute for Human Genetics and Biochemistry, Laboratory for AIDS Virus Research
New York
NY , 10065
USA


Henrik Ullums
Department of Clinical Immunology
Copenhagen University Hospital, Rigshospitalet
Copenhagen
Denmark


Bin Wang
Retroviral Genetics Division Center for Virus Research
Westmead Millennium Institute, Westmead Hospital
Sydney
NSW, 2145
Australia


Doris Wilflingseder
Department of Hygiene and Medical Microbiology
Innsbruck Medical University
Innsbruck, A-6020
Austria


Ronald Winston
Department of Medicine, Weill Medical College of Cornell University
Institute for Human Genetics and Biochemistry, Laboratory for AIDS Virus Research
New York, NY10065
USA


Jing Qin Wu
Retroviral Genetics Division Center for Virus Research
Westmead Millennium Institute, Westmead Hospital Westmead
Sydney
NSW, 2145
Australia


Li Zou
Retroviral Genetics Division Center for Virus Research
Westmead Millennium Institute,Westmead Hospital Westmead
Sydney
NSW, 2145
Australia




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