Preface

In the fields of chemistry, pharmaceuticals, food science, materials engineering, and environmental technology, cyclodextrins—in particular, beta-cyclodextrin (β-CD) and its derivatives—have become highly relevant. They can form inclusion complexes with a variety of guest molecules thanks to their special structural characteristics, which include a hydrophilic exterior and a hydrophobic cavity, improving solubility, stability, and bioavailability. Modifying β-CD to customize its properties for specific uses has been the focus of much research over the past few decades, which has resulted in advancements in drug delivery, catalysis, nanotechnology, and other fields. The goal of this book, β-Cyclodextrin and Its Derivatives: Preparation, Chemistry, and Applications, is to give researchers, academics, and professionals interested in the science and applications of β-CD a thorough and updated resource.

The book methodically discusses:

Methods for Synthesis and Modification: Comprehensive procedures for creating β-CD and its chemically altered derivatives, such as ethers, esters, and polymerized forms. Structural and Chemical Properties: An investigation of the kinetics, thermodynamics, and molecular interactions that control host-guest complexation. Numerous Applications: Real-world applications in advanced materials (e.g., sensors, nanocarriers), food and flavour stabilization, pharmaceuticals (e.g., drug encapsulation, controlled release), and environmental remediation (e.g., pollutant removal), etc. Chapters in the book offer both theoretical insights and helpful advice by fusing basic ideas with current developments. To close the gap between lab research and industrial application, special attention is paid to green chemistry techniques, synthesis scalability, and regulatory considerations.

For engineers, chemists, formulation scientists, and graduate students looking to capitalize on the potential of β-cyclodextrin derivatives, this book is meant to be a reference. In this ever-evolving field, we hope it stimulates more creativity and interdisciplinary cooperation.

Our appreciation goes out to the many researchers whose groundbreaking research has influenced our knowledge of cyclodextrins, as well as to the reviewers and contributors who have added their knowledge to this book.