The Gut-Brain Nexus: The Link Between Gut Microbiota and Neurodegenerative Diseases

Editors: Ajay Kumar, Avinash Kumar

The Gut-Brain Nexus: The Link Between Gut Microbiota and Neurodegenerative Diseases

ISBN: 979-8-89881-622-3
eISBN: 979-8-89881-621-6 (Online)

Introduction

Emerging evidence has established the gut microbiota as a key regulator of human health, influencing not only metabolism and immunity but also brain function through the complex gut-brain axis. Growing research suggests that disturbances in this bidirectional communication network may contribute to the onset and progression of several neurodegenerative disorders.

The Gut-Brain Nexus: The Link Between Gut Microbiota and Neurodegenerative Diseases provides a comprehensive overview of the emerging relationship between the gut microbiota and neurological health, highlighting its significance in the development and management of neurodegenerative disorders. Bringing together current scientific evidence and clinical perspectives, the book examines how the gut-brain axis influences brain function and explores the mechanisms through which alterations in the gut microbiome may contribute to disease onset and progression. It is intended as a valuable reference for researchers, healthcare professionals and students interested in neuroscience, microbiology and translational medicine.

The chapters examine the role of the gut microbiota in neurological disorders, including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis, while also discussing irritable bowel syndrome in the context of the gut-brain axis. The book further explores microbiota-based therapeutic strategies, including probiotics, prebiotics and synbiotics, alongside dietary and lifestyle interventions, commercially available products and current challenges in microbiome modulation. Together, these topics provide readers with a balanced understanding of the therapeutic potential and future directions of gut microbiota research in neurodegenerative diseases.


Target Readership :

Researchers, healthcare professionals and general readers.

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