Metals and Neurological Disorders: Exploring Neurotoxicity Mechanisms and Receptor Targets

Metals and Neurological Disorders is a comprehensive exploration of how metal exposure impacts the human nervous system, both physiologically and pathologically. This multidisciplinary volume bridges toxicology, neurobiology, pharmacology, and clinical research to illuminate the complex interactions between metals and neural tissues.

The book begins with fundamental principles of metal homeostasis and progresses through exposure pathways, mechanisms of neurotoxicity, and the pathophysiology of metal-induced neurological disorders. It includes dedicated chapters on metals such as aluminium, lead, and iron, which are commonly implicated in neurodegenerative conditions. Advanced topics cover biomarkers, neuropsychological assessments, and imaging techniques for early diagnosis and targeted intervention.

Emerging tools and strategies such as nanotechnology, nutritional and lifestyle interventions, and translational research are highlighted, providing a bridge from benchside findings to clinical applications. The content is supported with clear diagrams, real-world examples, and up-to-date references, making it both academically rigorous and practically relevant.

Key Features

- In-depth coverage of metal homeostasis, neurotoxicity mechanisms, and receptor-level interactions.
- Detailed analysis of specific metals (aluminium, lead, iron) and their role in neurological disorders.
- Examination of biomarkers, neuropsychological assessments, and advanced imaging for early diagnosis.
- Explores translational research, clinical trials, and emerging therapeutic strategies.
- Focuses on practical interventions, including nutritional, lifestyle, and nanotechnology-based approaches.
- Multidisciplinary perspectives connecting toxicology, neuroscience, medicine, and pharmacology.

Target Readership :

Students, academics, researchers, and professionals in medicine, neuroscience, pharmacology, and toxicology.

Editor(s):

Shamsher Singh
Neuroscience Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Contributor(s):

Ajay Bommareddy
Biomedical Science Department
Schmidt College of Medicine, Florida Atlantic University
Boca Raton, Florida
USA

Ajay Singh Kushwah
Department of Pharmacology
Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy
Bela, Punjab
India

Anil Kumar
Pharmacology Division
University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Panjab University
Chandigarh
India

Balwinder Kaur
Department of Chemistry
Punjabi University
Patiala, Punjab
India

Dhrita Chatterjee
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Dhruva Kumar
Department of Chemistry
Guru Nanak College
Budhlada, Punjab
India

Falguni Goel
Department of Pharmaceutical Technology
Meerut Institute of Engineering & Technology (MIET)
Meerut
India

G.D Gupta
Department of Pharmaceutics
ISF College of Pharmacy
Moga, Punjab
India

Garima Sharma
Pharmacology Division
University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Panjab University
Chandigarh
India

Kamal Preet Mehra
Department of Pharmacology
RIMT University
Sirhind, Mandi Gobindgarh, Punjab
India

Karan Sharma
Department of Pharmacology
Shiva Institute of Pharmacy
Bilaspur, Himachal Pradesh
India

Khadga Raj Aran
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Komal Komal
Department of Pharmaceutics
ISF College of Pharmacy
Moga, Punjab
India

Kousik Maparu
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Kousik Maparu
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Lav Goyal
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Lovekesh Singh
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Medha Bhalla
Department of Pharmacology
Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy
Bela, Punjab
India

Naga Rani Kagithala
School of Medical & Allied Sciences, Department of Pharmacy
Galgotias University
Greater Noida, Uttar Pradesh
India

Navpreet Kaur
Department of Pharmacy Practice
ISF College of Pharmacy
Moga, Punjab
India

Neelam Sharma
Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy (An Autonomous College)

BELA (Ropar), Punjab
India

Nileshwar Kalia
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Pavittar Singh
Department of Pharmaceutical Analysis
ISF College of Pharmacy
Moga, Punjab
India

Prem Shankar Mishra
School of Medical & Allied Sciences, Department of Pharmacy
Galgotias University
Greater Noida, Uttar Pradesh
India

R.K. Narang
Department of Pharmaceutics
ISF College of Pharmacy
Moga, Punjab
India

Rahul Kumar
School of Medical & Allied Sciences, Department of Pharmacy
Galgotias University
Greater Noida, Uttar Pradesh
India

Rahul Kumar Sharma
Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy (An Autonomous College)

BELA (Ropar), Punjab
India

Rajesh Kumar
Department of Chemistry
Govt. Degree College Khundian
District Kangra, HP
India

Ramandeep Kaur
Department of Pharmacy Practice
ISF College of Pharmacy
Moga, Punjab
India

Ramandeep Kaur
Department of Pharmacology
Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy
Bela, Punjab
India

Ravina Kumari
Department of Pharmacology
Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy
Bela, Punjab
India

Ritu Kainth
Department of Pharmacology
Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy
Bela, Punjab
India

Romanpreet Kaur
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

S.K. Abdul Rahaman
School of Medical & Allied Sciences, Department of Pharmacy
Galgotias University
Greater Noida, Uttar Pradesh
India

Sakshi Patel
School of Medical & Allied Sciences, Department of Pharmacy
Galgotias University
Greater Noida, Uttar Pradesh
India

Sanchi Jain
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Sania Grover
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Shamsher Singh
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Shilpa Thakur
Department of Pharmacology
Shiva Institute of Pharmacy
Bilaspur, Himachal Pradesh
India

Subhash Chand
Department of Chemistry
Lajpat Rai D.A.V College
Jagraon, Punjab
India

Sudarshan Kumar
Department of Pharmaceutical Analysis
ISF College of Pharmacy
Moga, Punjab
India

Suraj Sharma
Pharmacology Division
University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Panjab University
Chandigarh
India

Tanya Vats
Neuropharmacology Division, Department of Pharmacology
ISF College of Pharmacy
Moga, Punjab
India

Vaishali Dobhal
Motherhood University
Roorkee, Uttarakhand
India

Vipin Kumar Garg
Department of Pharmaceutical Technology
Meerut Institute of Engineering & Technology (MIET)
Meerut
India

Vivek Asati
Department of Pharmaceutical Analysis
ISF College of Pharmacy
Moga, Punjab
India

Yukti Mittal
Department of Pharmacy Practice
ISF College of Pharmacy
Moga, Punjab
India

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