Editor: Habibe Yilmaz

Series Title: Recent Advances in Biotechnology

Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective

Volume 8

eBook: US $79 Special Offer (PDF + Printed Copy): US $145
Printed Copy: US $105
Library License: US $316
ISBN: 978-981-5179-43-9 (Print)
ISBN: 978-981-5179-42-2 (Online)
Year of Publication: 2023
DOI: 10.2174/97898151794221230801

Introduction

Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective offers a comprehensive exploration of the dynamic field of pharmaceutical nanobiotechnology, focusing on its medical applications. This edited reference serves as a valuable resource for researchers, students, and professionals in various disciplines (pharmacology, biotechnology, clinical medicine and nanotechnology) , providing insights into the latest advancements and practical implications of nanotechnology in the pharmaceutical sector.

The book presents 14 edited and referenced chapters that cover several themes for readers.

1. General Pharmaceutical Nanobiotechnology:

  • - Introduction to the interdisciplinary field
  • - Exploration of nanoscale materials for medical purposes

2. Nanoparticle Development and Applications:

  • - Bioinspired Nanomedicines
  • - Lipid-Based Nanocarriers
  • - Metallic Nanoparticles and Their Applications
  • - Nanoparticle Targeting Strategies
  • - Nanomedicine-Based Therapies for Cancer Stem Cells

3. Biotechnological Aspects:

  • - Biotechnological Significance of Exosomes
  • - Glycoconjugates: Biosynthesis and Functions

4. Innovative Nanotherapies:

  • - Novel Nanotechnological Approaches for Glioblastoma
  • - Biocompatibility of Nanomedicines and Bio Corona

5. Diagnostic and Sensing Applications:

  • - Role of Nanoparticular/Nano Vesicular Systems as Biosensors
  • - In Vitro Applications of Drug-Carrying Nanoparticles in Cell Culture Studies
  • - In Vivo Imaging Techniques: Bioluminescence and Fluorescence Imaging

6. Precision Medicine:

  • - The Role of Nano and Biopharmaceutics in Precision Medicine

Audience: Postgraduate researchers in pharmaceutical biotechnology; pharmacy professionals and academicians.

Preface

Biotechnology is a science that has many application areas such as medical, microbial, forensic, plant, agricultural, marine and food. In recent years, developments in the medical biotechnology field have accelerated. In particular, with the emergence of knowledge on the molecular and biochemical basis of diseases, biotechnological drugs have been preferred over conventional drugs. With the development of omics technologies, our increasing knowledge about diseases has revealed that diseases should be handled individually rather than in general. This, in turn, has given rise to precision medicine and the need for more specific tools for more effective treatment. Based on this information, the range of pharmaceutical products developed by medical biotechnology has expanded from recombinant proteins to nano drug delivery systems. Nanobiotechnological approaches allow many alternatives in terms of both treatment and diagnosis. There are many advantages going down to nano sizes, such as targeting, selecting, and penetrating a single cell, and providing more effective treatment with a lower drug dose.

This book aims to give the reader general information about some of the current therapeutic and diagnostic nanopharmaceutical products as well as their in vitro and in vivo applications. The reader will be able to grasp the wide possibilities and most current applications of nanobiotechnology.

Many different nanodrug systems, such as biomimetic systems, lipid and metallic nanoparticles, exosomes and glycoconjugates and photodynamic therapy, are included. In addition, information about the emergence of nanobiotechnology in personalized therapy, nanobiotechnological approaches in cancer stem cells and glioblastoma, and their use as biosensors will be conveyed. Emphasizing the importance of the biocompatibility and toxicological profile of these products, information about the relationship and modulation of bio corona, which is one of the most current issues of recent years, will also be included. Following targeting strategies, which is one of the most important advantages of nanodrugs, the book is concludes with two chapters on in vitro and in vivo studies of nanopharmaceuticals.

The application areas and tools of nanobiotechnology are so wide that it has not been possible to include them all in this book. However, we expect that readers will be informed about the most current and promising approaches to nanobiotechnology from a medical point of view.

Habibe Yilmaz
Department of Pharmaceutical Biotechnology
Faculty of Pharmacy
Trakya University
Edirne
Türkiye